Drug-related delirium in elderly patients;Medikamenten-induzierte Delirien älterer Menschen

Wiener Medizinische Wochenschrift

Volumn 160, Issue 11-12, 2010, Pages 281-285

  Iglseder, Bernhard ^a   Dovjak, Peter ^b   Benvenuti Falger, Ursula ^c   Böhmdorfer, Birgit ^d   Lechleitner, Monika ^c   Otto, Ronald ^e   Roller, Regina E ^e   Sommeregger, Ulrike ^d   Gosch, Markus ^c  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

^b Abteilung fur Akutgeriatrie/Remobilisation   (Austria)

^c Hospital Hochzirl   (Austria)

^d Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhugel   (Austria)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Acetylcholine; Acute confusional state; Delirium; Inappropriate medication

Indexed keywords

AMFEBUTAMONE; ANALGESIC AGENT; ANTIDIABETIC AGENT; ANTIPARKINSON AGENT; ATROPINE; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA LACTAM ANTIBIOTIC; DIGITALIS; DIURETIC AGENT; GLUTAMIC ACID; HISTAMINE H2 RECEPTOR ANTAGONIST; LEVODOPA; LITHIUM; NARCOTIC AGENT; NEUROLEPTIC AGENT; NEUROTRANSMITTER; NONSTEROID ANTIINFLAMMATORY AGENT; OXYBUTYNIN; QUINOLONE; SCOPOLAMINE; THEOPHYLLINE; TRANQUILIZER; TRICYCLIC ANTIDEPRESSANT AGENT;

ANTICHOLINERGIC EFFECT; ARTICLE; CHOLINERGIC TRANSMISSION; COGNITION; DELIRIUM; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; ELECTROENCEPHALOGRAM; GERIATRIC DISORDER; HUMAN; PATHOGENESIS;

EID: 77957317072     PISSN: 00435341     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10354-010-0787-0     Document Type: Article

References (22)

1. American Psychiatric Assiciation WD. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. APA. 1994
2. JD Gaudreau P Gagnon MA Roy F Harel A Tremblay 2005 Association between psychoactive medications and delirium in hospitalized patients: a critical review Psychosomatics 46 4 302 316 10.1176/appi.psy.46.4.302 16000673 (Pubitemid 41472628)
3. K Alagiakrishnan CA Wiens 2004 An approach to drug induced delirium in the elderly Postgrad Med J 80 945 388 393 10.1136/pgmj.2003.017236 1:CAS:528:DC%2BD2cXmvF2nsbo%3D 15254302 (Pubitemid 38961859)
4. ST O'Keeffe JN Lavan 1999 Clinical significance of delirium subtypes in older people Age Ageing 28 2 115 119 10.1093/ageing/28.2.115 10350406 (Pubitemid 29161214)
5. N Siddiqi AO House JD Holmes 2006 Occurrence and outcome of delirium in medical in-patients: a systematic literature review Age Ageing 35 4 350 364 10.1093/ageing/afl005 16648149 (Pubitemid 43941802)
6. SK Inouye MJ Schlesinger TJ Lydon 1999 Delirium: a symptom of how hospital care is failing older persons and a window to improve quality of hospital care Am J Med 106 5 565 573 10.1016/S0002-9343(99)00070-4 1:STN:280:DyaK1M3ms1Olsw%3D%3D 10335730 (Pubitemid 29231109)
7. J Young SK Inouye 2007 Delirium in older people BMJ 334 7598 842 846 10.1136/bmj.39169.706574.AD 17446616 (Pubitemid 46706931)
8. SK Inouye CH van Dyck CA Alessi S Balkin AP Siegal RI Horwitz 1990 Clarifying confusion: the confusion assessment method. A new method for detection of delirium Ann Intern Med 113 12 941 948 1:STN:280: DyaK3M%2Flt1yisQ%3D%3D 2240918
9. SK Inouye 2006 Delirium in older persons N Engl J Med 354 11 1157 1165 10.1056/NEJMra052321 1:CAS:528:DC%2BD28XisFemsrc%3D 16540616
10. JM Flacker V Cummings JR Mach Jr K Bettin DK Kiely J Wei 1998 The association of serum anticholinergic activity with delirium in elderly medical patients Am J Geriatr Psychiatry 6 1 31 41 1:STN:280:DyaK1c7jtVCltg%3D%3D 9469212
11. TT Hshieh TG Fong ER Marcantonio SK Inouye 2008 Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence J Gerontol A Biol Sci Med Sci 63 7 764 772 18693233
12. T Itil M Fink 1966 Anticholinergic drug-induced delirium: experimental modification, quantitative EEG and behavioral correlations J Nerv Ment Dis 143 6 492 507 10.1097/00005053-196612000-00005 1:CAS:528:DyaF2sXmsVakug%3D%3D 5964304
13. H Nagasawa T Araki K Kogure 1994 Alteration of muscarinic acetylcholine binding sites in the postischemic brain areas of the rat using in?vitro autoradiography J Neurol Sci 121 1 27 31 10.1016/0022-510X(94)90152-X 1:CAS:528:DyaK2cXis1Wqur0%3D 8133308 (Pubitemid 24025242)
14. PT Trzepacz 1999 Update on the neuropathogenesis of delirium Dement Geriatr Cogn Disord 10 5 330 334 10.1159/000017164 1:STN:280: DyaK1MvgslWjuw%3D%3D 10473933 (Pubitemid 29403589)
15. M Jaber SW Robinson C Missale MG Caron 1996 Dopamine receptors and brain function Neuropharmacology 35 11 1503 1519 10.1016/S0028-3908(96)00100-1 1:CAS:528:DyaK2sXos12qsQ%3D%3D 9025098 (Pubitemid 27026480)
16. MV Rudorfer HK Manji WZ Potter 1991 Bupropion, ECT, and dopaminergic overdrive Am J Psychiatry 148 8 1101 1102 1:STN:280:DyaK3MzgslSgug%3D%3D 1906685
17. CV Wetli D Mash SB Karch 1996 Cocaine-associated agitated delirium and the neuroleptic malignant syndrome Am J Emerg Med 14 4 425 428 10.1016/S0735-6757(96)90066-2 1:STN:280:DyaK28zjtFWmtw%3D%3D 8768172 (Pubitemid 26240854)
18. EW Boyer M Shannon 2005 The serotonin syndrome N Engl J Med 352 11 1112 1120 10.1056/NEJMra041867 1:CAS:528:DC%2BD2MXit1OjsL8%3D 15784664 (Pubitemid 40365352)
19. TT Levin A Cortes-Ladino M Weiss ML Palomba 2008 Life-threatening serotonin toxicity due to a citalopram-fluconazole drug interaction: case reports and discussion Gen Hosp Psychiatry 30 4 372 377 10.1016/j.genhosppsych. 2008.03.008 18585543 (Pubitemid 351862318)
20. B Kiangkitiwan A Doppalapudi M Fonder K Solberg B Bohner 2008 Levofloxacin-induced delirium with psychotic features Gen Hosp Psychiatry 30 4 381 383 10.1016/j.genhosppsych.2007.11.003 18585545 (Pubitemid 351862308)
21. MH Hopkins RB Silverman 1992 Beta-lactams: a new class of conformationally-rigid inhibitors of gamma-aminobutyric acid aminotransferase J Enzyme Inhib 6 2 125 129 10.3109/14756369209040743 1:CAS:528: DyaK3sXntlWhsA%3D%3D 1284428
22. KM Campbell DS Schubert 1991 Delirium after cessation of glucocorticoid therapy Gen Hosp Psychiatry 13 4 270 272 10.1016/0163-8343(91)90129-K 1:STN:280:DyaK3MzktVWhsA%3D%3D 1874429