Tandem laser-induced fluorescence and mass spectrometry detection for high-performance liquid chromatography analysis of the in vitro metabolism of doxorubicin

Analytical Chemistry

Volumn 82, Issue 19, 2010, Pages 8113-8120

  Katzenmeyer, Joseph B ^a   Eddy, Christopher V ^a   Arriaga, Edgar A ^a  

^a University of Minnesota   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTES; COMPLEX SAMPLES; DETECTION SCHEME; DOXORUBICIN; IN-VITRO; LASER INDUCED FLUORESCENCE; METABOLIC PRODUCTS; MS DETECTION; RAT LIVERS; STRUCTURAL CHARACTERIZATION;

BIOCHEMISTRY; CHROMATOGRAPHY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LASER PRODUCED PLASMAS; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES;

DETECTORS;

7 DEOXY 13 DIHYDROADRIAMYCINONE; 7 DEOXYADRIAMYCIN AGLYCONE; 7-DEOXY-13-DIHYDROADRIAMYCINONE; 7-DEOXYADRIAMYCIN AGLYCONE; ANTINEOPLASTIC ANTIBIOTIC; DOXORUBICIN; DRUG DERIVATIVE; FLUORESCENT DYE; NAPHTHACENE DERIVATIVE;

ANIMAL; ARTICLE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LASER; LIVER; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOXORUBICIN; FLUORESCENT DYES; LASERS; LIVER; MASS SPECTROMETRY; NAPHTHACENES; RATS;

EID: 77957305694     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac1011415     Document Type: Article

References (29)

1. Crow, F. W., Cragun, J. D., Johnson, K. L., Ruiz, M. V., Posada De La Paz, M., and Naylor, S. Biomed. Chromatogr. 2002, 16, 311-318
2. Akbay, C., Rizvi, S. A., and Shamsi, S. A. Anal. Chem. 2005, 77, 1672-1683
3. Huhn, C., Neususs, C., Pelzing, M., Pyell, U., Mannhardt, J., and Putz, M. Electrophoresis 2005, 26, 1389-1397
4. Gennaro, L. A. and Salas-Solano, O. Anal. Chem. 2008, 80, 3838-3845
5. Wieing, J. Chromatographia 2002, 55, 107-113
6. Anderson, A. B. and Arriaga, E. A. J. Chromatogr. B 2004, 808, 295-302
7. Andrews, P. A., Brenner, D. E., Chou, F. T., Kubo, H., and Bachur, N. R. Drug Metab. Dispos. 1980, 8, 152-156
8. Colombo, T., Donelli, M. G., Urso, R., Dallarda, S., Bartosek, I., and Guaitani, A. Exp. Gerontol. 1989, 24, 159-171
9. Minotti, G., Licata, S., Saponiero, A., Menna, P., Calafiore, A. M., Di Giammarco, G., Liberi, G., Animati, F., Cipollone, A., Manzini, S., and Maggi, C. A. Chem. Res. Toxicol. 2000, 13, 1336-1341
10. Lachatre, F., Marquet, P., Ragot, S., Gaulier, J. M., Cardot, P., and Dupuy, J. L. J. Chromatogr. B, Biomed. Sci. Appl. 2000, 738, 281-291
11. Liu, Y., Yang, Y., Liu, X., and Jiang, T. Talanta 2008, 74, 887-895
12. Anderson, A. B., Ciriacks, C. M., Fuller, K. M., and Arriaga, E. A. Anal. Chem. 2003, 75, 8-15
13. Mross, K., Maessen, P., van der Vijgh, W. J., Gall, H., Boven, E., and Pinedo, H. M. J. Clin. Oncol. 1988, 6, 517-526
14. Urva, S. R., Shin, B. S., Yang, V. C., and Balthasar, J. P. J. Chromatogr. B 2009, 877, 837-841
15. Coleman, S., Liu, S., Linderman, R., Hodgson, E., and Rose, R. L. Chem.-Biol. Interact. 1999, 122, 27-39
16. Sheets, J. J., Schmidt, A., Samaritoni, J. G., and Gifford, J. M. J. Agric. Food Chem. 1997, 45, 4826-4832
17. Tani, N., Yabuki, M., Komuro, S., and Kanamaru, H. Xenobiotica 2005, 35, 1121-1133
18. Licata, S., Saponiero, A., Mordente, A., and Minotti, G. Chem. Res. Toxicol. 2000, 13, 414-420
19. Golay, M. J. E. In Gas Chromatography; Hesty, D. H., Ed.; Academic Press: New York, 1958; p 36.
20. Sternberg, J. C. Adv. Chromatogr. 1966, 2, 205-270
21. Leslie, A. D. and Volmer, D. A. Spectroscopy 2007, 22, 32-39
22. Takanashi, S. and Bachur, N. R. J. Pharmacol. Exp. Ther. 1975, 195, 41-49
23. Minotti, G., Menna, P., Salvatorelli, E., Cairo, G., and Gianni, L. Pharmacol. Rev. 2004, 56, 185-229
24. Singh, K. K., Russell, J., Sigala, B., Zhang, Y., Williams, J., and Keshav, K. F. Oncogene 1999, 18, 6641-6646
25. Sokolove, P. M. Arch. Biochem. Biophys. 1991, 284, 292-297
26. Sokolove, P. M. Int. J. Biochem. 1994, 26, 1341-1350
27. Nolin, T. D., Naud, J., Leblond, F. A., and Pichette, V. Clin. Pharmacol. Ther. 2008, 83, 898-903
28. Kiechel, J. R. Gerontology 1982, 28, 101-112
29. Takanashi, S. and Bachur, N. R. Drug Metab. Dispos. 1976, 4, 79-87