Characterization of the enzymes involved in the in vitro metabolism of amrubicin hydrochloride

Xenobiotica

Volumn 35, Issue 12, 2005, Pages 1121-1133

  Tani, N ^a   Yabuki, M ^a   Komuro, S ^a   Kanamaru, H ^a  

^a SUMITOMO CHEMICAL CO LTD   (Japan)

Author keywords

Amrubicin hydrochloride; Carbonyl reductase; Cisplatin; NADPH cytochrome P450 reductase; NADPH:quinone oxidoreductase

Indexed keywords

AMRUBICIN; AMRUBICINOL; ANTINEOPLASTIC ANTIBIOTIC; CARBONYL REDUCTASE; CISPLATIN; DICOUMAROL; OXIDOREDUCTASE; QUERCETIN; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOSOL; DEGLYCOSYLATION; DRUG METABOLISM; ENZYME ANALYSIS; IN VITRO STUDY; INCUBATION TIME; LIVER MICROSOME; LIVER MICROSOME METABOLISM; MALE; NONHUMAN; RAT; REDUCTION;

ADULT; AGED; ANIMALS; ANTHRACYCLINES; CISPLATIN; CYTOSOL; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; MICROSOMES, LIVER; MIDDLE AGED; MODELS, BIOLOGICAL; RATS; TIME FACTORS;

EID: 31544435787     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250500342746     Document Type: Article

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