Screening procedure for detection of stimulant laxatives and/or their metabolites in human urine using gas chromatography-mass spectrometry after enzymatic cleavage of conjugates and extractive methylation

Therapeutic Drug Monitoring

Volumn 27, Issue 2, 2005, Pages 151-157

  Beyer, Jochen ^a   Peters, Frank T ^a   Maurer, Hans H ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Extractive methylation; Gas chromatography mass spectrometry; Laxatives; Screening; Urine

Indexed keywords

ANTHRAQUINONE DERIVATIVE; BISACODYL; BISACODYL DIPHENOL; DRUG METABOLITE; LAXATIVE; PHENOLPHTHALEIN; PICOSULFATE SODIUM; RHEIN; SENNA EXTRACT; SENNOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DRUG DETERMINATION; DRUG MONITORING; DRUG SCREENING; DRUG URINE LEVEL; ENTEROPATHY; ENZYME DEGRADATION; GAS CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; NORMAL HUMAN; PHASE TRANSITION; PRIORITY JOURNAL; REFERENCE VALUE; SCREENING TEST; SOLID PHASE EXTRACTION; TOXICOLOGICAL PARAMETERS; URINALYSIS;

ANTHRAQUINONES; BISACODYL; CATHARTICS; DRUG MONITORING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; PHENOLPHTHALEIN; PICOLINES; SENNA EXTRACT; SENSITIVITY AND SPECIFICITY; SPECIMEN HANDLING; URINALYSIS;

EID: 16244403650     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ftd.0000150878.36296.04     Document Type: Article

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