In vitro and in vivo anti-Trypanosoma brucei activities of phenazinomycin and related compounds

Journal of Antibiotics

Volumn 63, Issue 9, 2010, Pages 579-581

  Otoguro, Kazuhiko ^a   Ishiyama, Aki ^a   Iwatsuki, Masato ^a   Namatame, Miyuki ^a   Nishihara Tukashima, Aki ^a   Nakashima, Takuji ^a   Shibahara, Seiji ^b   Kondo, Shinichi ^c   Yamada, Haruki ^a   Ömura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b Nimura Genetic Solutions   (Japan)

^c Bioscience Associates   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,6 DIMETHOXYPHENAZINE; ANTITRYPANOSOMAL AGENT; CLOFAZIMINE; EFLORNITHINE; GRISEOLUTEIC; GRISEOLUTEIC B; LAVANDUCYANIN; PHENAZINE; PHENAZINE 5 OXIDE; PHENAZINOMYCIN; SURAMIN; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; PHENAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CYTOTOXICITY; DNA SYNTHESIS; DRUG ACTIVITY; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; EMBRYO CELL; FUNGAL STRAIN; IC 50; IN VITRO STUDY; LETTER; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS; ANIMAL; CHEMICAL STRUCTURE; DISEASE MODEL; DRUG EFFECTS; DRUG SENSITIVITY; IC50; TREATMENT OUTCOME; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

TRYPANOSOMA BRUCEI;

ANIMALS; ANTIPROTOZOAL AGENTS; DISEASE MODELS, ANIMAL; INHIBITORY CONCENTRATION 50; MICE; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PHENAZINES; TREATMENT OUTCOME; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

EID: 77957302452     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2010.72     Document Type: Letter

References (13)

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