메뉴 건너뛰기




Volumn 400, Issue 4, 2010, Pages 476-482

Inactivation of Smad4 leads to impaired ocular development and cataract formation

Author keywords

Eyelid closure failure; Lens; Ocular development; Smad4

Indexed keywords

CRE RECOMBINASE; SMAD4 PROTEIN; TRANSCRIPTION FACTOR PAX6;

EID: 77957268760     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.08.065     Document Type: Article
Times cited : (16)

References (28)
  • 3
    • 0032430772 scopus 로고    scopus 로고
    • BMP4 is essential for lens induction in the mouse embryo
    • Furuta Y., Hogan B.L. BMP4 is essential for lens induction in the mouse embryo. Genes Dev. 1998, 12:3764-3775.
    • (1998) Genes Dev. , vol.12 , pp. 3764-3775
    • Furuta, Y.1    Hogan, B.L.2
  • 4
    • 0036340690 scopus 로고    scopus 로고
    • The role of bone morphogenetic proteins in the differentiation of the ventral optic cup
    • Adler R., Belecky-Adams T.L. The role of bone morphogenetic proteins in the differentiation of the ventral optic cup. Development 2002, 129:3161-3171.
    • (2002) Development , vol.129 , pp. 3161-3171
    • Adler, R.1    Belecky-Adams, T.L.2
  • 5
    • 0036672240 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation
    • Belecky-Adams T.L., Adler R., Beebe D.C. Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development 2002, 129:3795-3802.
    • (2002) Development , vol.129 , pp. 3795-3802
    • Belecky-Adams, T.L.1    Adler, R.2    Beebe, D.C.3
  • 6
    • 0036677580 scopus 로고    scopus 로고
    • Bmp signaling is required for development of primary lens fiber cells
    • Faber S.C., Robinson M.L., Makarenkova H.P., Lang R.A. Bmp signaling is required for development of primary lens fiber cells. Development 2002, 129:3727-3737.
    • (2002) Development , vol.129 , pp. 3727-3737
    • Faber, S.C.1    Robinson, M.L.2    Makarenkova, H.P.3    Lang, R.A.4
  • 7
    • 33846583365 scopus 로고    scopus 로고
    • The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup
    • Behesti H., Holt J.K., Sowden J.C. The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup. BMC Dev. Biol. 2006, 6:62.
    • (2006) BMC Dev. Biol. , vol.6 , pp. 62
    • Behesti, H.1    Holt, J.K.2    Sowden, J.C.3
  • 8
    • 33747615066 scopus 로고    scopus 로고
    • Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH
    • Morcillo J., Martinez-Morales J.R., Trousse F., et al. Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH. Development 2006, 133:3179-3190.
    • (2006) Development , vol.133 , pp. 3179-3190
    • Morcillo, J.1    Martinez-Morales, J.R.2    Trousse, F.3
  • 9
    • 0030690337 scopus 로고    scopus 로고
    • Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
    • Liu F., Pouponnot C., Massague J. Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. Genes Dev. 1997, 11:3157-3167.
    • (1997) Genes Dev. , vol.11 , pp. 3157-3167
    • Liu, F.1    Pouponnot, C.2    Massague, J.3
  • 10
    • 19944386897 scopus 로고    scopus 로고
    • Contributions by members of the TGFbeta superfamily to lens development
    • Beebe D.C., Garcia C., Wang X., et al. Contributions by members of the TGFbeta superfamily to lens development. Int. J. Dev. Biol. 2004, 48:845-856.
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 845-856
    • Beebe, D.C.1    Garcia, C.2    Wang, X.3
  • 11
    • 33645067959 scopus 로고    scopus 로고
    • Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells
    • Ittner L.M., Wurdak H., Schwerdtfeger K., et al. Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells. J. Biol. 2005, 4:11.
    • (2005) J. Biol. , vol.4 , pp. 11
    • Ittner, L.M.1    Wurdak, H.2    Schwerdtfeger, K.3
  • 12
    • 0041573044 scopus 로고    scopus 로고
    • Reduced programmed cell death in the retina and defects in lens and cornea of Tgfbeta2(-/-) Tgfbeta3(-/-) double-deficient mice
    • Dunker N., Krieglstein K. Reduced programmed cell death in the retina and defects in lens and cornea of Tgfbeta2(-/-) Tgfbeta3(-/-) double-deficient mice. Cell Tissue Res. 2003, 313:1-10.
    • (2003) Cell Tissue Res. , vol.313 , pp. 1-10
    • Dunker, N.1    Krieglstein, K.2
  • 13
    • 4444249320 scopus 로고    scopus 로고
    • Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo
    • Chu G.C., Dunn N.R., Anderson D.C., et al. Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo. Development 2004, 131:3501-3512.
    • (2004) Development , vol.131 , pp. 3501-3512
    • Chu, G.C.1    Dunn, N.R.2    Anderson, D.C.3
  • 14
    • 0034312313 scopus 로고    scopus 로고
    • Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
    • Ashery-Padan R., Marquardt T., Zhou X., Gruss P. Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev. 2000, 14:2701-2711.
    • (2000) Genes Dev. , vol.14 , pp. 2701-2711
    • Ashery-Padan, R.1    Marquardt, T.2    Zhou, X.3    Gruss, P.4
  • 15
    • 0035195501 scopus 로고    scopus 로고
    • The upstream ectoderm enhancer in Pax6 has an important role in lens induction
    • Dimanlig P.V., Faber S.C., Auerbach W., et al. The upstream ectoderm enhancer in Pax6 has an important role in lens induction. Development 2001, 128:4415-4424.
    • (2001) Development , vol.128 , pp. 4415-4424
    • Dimanlig, P.V.1    Faber, S.C.2    Auerbach, W.3
  • 16
    • 0028832707 scopus 로고
    • A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye
    • Dudley A.T., Lyons K.M., Robertson E.J. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995, 9:2795-2807.
    • (1995) Genes Dev. , vol.9 , pp. 2795-2807
    • Dudley, A.T.1    Lyons, K.M.2    Robertson, E.J.3
  • 17
    • 0033105981 scopus 로고    scopus 로고
    • BMP7 acts in murine lens placode development
    • Wawersik S., Purcell P., Rauchman M., et al. BMP7 acts in murine lens placode development. Dev Biol. 1999, 207:176-188.
    • (1999) Dev Biol. , vol.207 , pp. 176-188
    • Wawersik, S.1    Purcell, P.2    Rauchman, M.3
  • 18
    • 0031561724 scopus 로고    scopus 로고
    • BMP7 null mutation in mice Developmental defects in skeleton, kidney, and eye
    • Jena N., Martin-Seisdedos C., McCue P., Croce C.M. BMP7 null mutation in mice Developmental defects in skeleton, kidney, and eye. Exp. Cell Res. 1997, 230:28-37.
    • (1997) Exp. Cell Res. , vol.230 , pp. 28-37
    • Jena, N.1    Martin-Seisdedos, C.2    McCue, P.3    Croce, C.M.4
  • 19
    • 0030609894 scopus 로고    scopus 로고
    • TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    • Sanford L.P., Ormsby I., Gittenberger-de Groot A.C., et al. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 1997, 124:2659-2670.
    • (1997) Development , vol.124 , pp. 2659-2670
    • Sanford, L.P.1    Ormsby, I.2    Gittenberger-de Groot, A.C.3
  • 20
    • 0028176755 scopus 로고
    • Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction
    • Vassalli A., Matzuk M.M., Gardner H.A., et al. Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction. Genes Dev. 1994, 8:414-427.
    • (1994) Genes Dev. , vol.8 , pp. 414-427
    • Vassalli, A.1    Matzuk, M.M.2    Gardner, H.A.3
  • 21
    • 0028015934 scopus 로고
    • Mice homozygous for a null mutation of activin beta B are viable and fertile
    • Schrewe H., Gendron-Maguire M., Harbison M.L., Gridley T. Mice homozygous for a null mutation of activin beta B are viable and fertile. Mech. Dev. 1994, 47:43-51.
    • (1994) Mech. Dev. , vol.47 , pp. 43-51
    • Schrewe, H.1    Gendron-Maguire, M.2    Harbison, M.L.3    Gridley, T.4
  • 22
    • 0042237016 scopus 로고    scopus 로고
    • A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure
    • Zhang L., Wang W., Hayashi Y., et al. A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure. Embo. J. 2003, 22:4443-4454.
    • (2003) Embo. J. , vol.22 , pp. 4443-4454
    • Zhang, L.1    Wang, W.2    Hayashi, Y.3
  • 23
    • 11144300244 scopus 로고    scopus 로고
    • MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration
    • Zhang L., Deng M., Parthasarathy R., et al. MEKK1 transduces activin signals in keratinocytes to induce actin stress fiber formation and migration. Mol. Cell Biol. 2005, 25:60-65.
    • (2005) Mol. Cell Biol. , vol.25 , pp. 60-65
    • Zhang, L.1    Deng, M.2    Parthasarathy, R.3
  • 24
    • 4143135554 scopus 로고    scopus 로고
    • The signaling pathways in tissue morphogenesis a lesson from mice with eye-open at birth phenotype
    • Xia Y., Kao W.W. The signaling pathways in tissue morphogenesis a lesson from mice with eye-open at birth phenotype. Biochem. Pharmacol. 2004, 68:997-1001.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 997-1001
    • Xia, Y.1    Kao, W.W.2
  • 25
    • 0034691062 scopus 로고    scopus 로고
    • MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation
    • Yujiri T., Ware M., Widmann C., et al. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation. Proc. Natl. Acad. Sci. USA 2000, 97:7272-7277.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7272-7277
    • Yujiri, T.1    Ware, M.2    Widmann, C.3
  • 26
    • 0038625108 scopus 로고    scopus 로고
    • JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure
    • Weston C.R., Wong A., Hall J.P., et al. JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes Dev. 2003, 17:1271-1280.
    • (2003) Genes Dev. , vol.17 , pp. 1271-1280
    • Weston, C.R.1    Wong, A.2    Hall, J.P.3
  • 27
    • 20144379401 scopus 로고    scopus 로고
    • ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles
    • Shimizu Y., Thumkeo D., Keel J., et al. ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J. Cell Biol. 2005, 16:941-953.
    • (2005) J. Cell Biol. , vol.16 , pp. 941-953
    • Shimizu, Y.1    Thumkeo, D.2    Keel, J.3
  • 28
    • 68549087379 scopus 로고    scopus 로고
    • FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate
    • Huang J., Dattilo L.K., Rajagopal R., et al. FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate. Development 2009, 136:1741-1750.
    • (2009) Development , vol.136 , pp. 1741-1750
    • Huang, J.1    Dattilo, L.K.2    Rajagopal, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.