Evelynin, a cytotoxic benzoquinone-type retro -dihydrochalcone from Tacca chantrieri

Journal of Natural Products

Volumn 73, Issue 9, 2010, Pages 1590-1592

  Peng, Jiangnan ^a   Jackson, Evelyn M ^a   Babinski, David J ^b   Risinger, April L ^a   Helms, Gregory ^c   Frantz, Doug E ^b   Mooberry, Susan L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOQUINONE DERIVATIVE; CHALCONE DERIVATIVE; EVELYNIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DIHYDROCHALCONE;

ALKYLATION; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IC 50; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MEDICINAL PLANT; MELANOMA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; PROSTATE CANCER; RHIZOME; TACCA CHANTRIERI; UTERINE CERVIX CARCINOMA; CHEMISTRY; DIOSCOREACEAE; DRUG SCREENING; HELA CELL LINE; IC50; ISOLATION AND PURIFICATION;

TACCA CHANTIERI;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZOQUINONES; CHALCONES; DIOSCOREACEAE; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; RHIZOME;

EID: 77957244136     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np100350s     Document Type: Article

References (18)

1. Cragg, G. M., Grothaus, P. G., and Newman, D. J. Chem. Rev. 2009, 109, 3012-3043
2. Newman, D. J. and Cragg, G. M. J. Nat. Prod. 2007, 70, 461-477
3. Tinley, T. L., Randall-Hlubek, D. A., Leal, R. M., Jackson, E. M., Cessac, J. W., Quada, J. C., Jr., Hemscheidt, T. K., and Mooberry, S. L. Cancer Res. 2003, 63, 3211-3220
4. Yokosuka, A., Mimaki, Y., Sakagami, H., and Sashida, Y. J. Nat. Prod. 2002, 65, 283-289
5. Chen, Z.-L., Shen, J.-H., Gao, Y.-S., and Wichtl, M. Planta Med. 1997, 63, 40-43
6. Abdel-Aziz, A. M., Brain, K. R., Blunden, G., Crabb, T., and Bashir, A. K. Planta Med. 1990, 56, 218-221
7. Yokosuka, A., Mimaki, Y., and Sashida, Y. Phytochemistry. 2002, 61, 73-78
8. Yokosuka, A., Mimaki, Y., and Sashida, Y. J. Nat. Prod. 2002, 65, 1293-1298
9. Yokosuka, A., Mimaki, Y., Sakuma, C., and Sashida, Y. Steroids 2005, 70, 257-265
10. Yokosuka, A. and Mimaki, Y. Chem. Pharm. Bull. (Tokyo) 2007, 55, 273-279
11. Yokosuka, A., Mimaki, Y., and Sashida, Y. J. Nat. Prod. 2003, 66, 876-878
12. Chen, Z.-L., Wang, B.-D., and Chen, M.-Q. Tetrahedron Lett. 1987, 28, 1673-1676
13. Chen, Z.-L., Wang, B.-D., and Shen, J.-H. Phytochemistry 1988, 27, 2999-3001
14. Risinger, A. L., Jackson, E. M., Polin, L. A., Helms, G. L., LeBoeuf, D. A., Joe, P. A., Hopper-Borge, E., Luduena, R. F., Kruh, G. D., and Mooberry, S. L. Cancer Res. 2008, 68, 8881-8888
15. Skehan, P., Storeng, R., Scudiero, D., Monks, A., McMahon, J., Vistica, D., Warren, J. T., Bokesch, H., Kenney, S., and Boyd, M. R. J. Natl. Cancer Inst. 1990, 82, 1107-1112
16. Jacobsen, N. Organic Syntheses; Wiley: New York, 1988, Coll. Vol. 6, p 890.
17. For a recent example of this approach, see
18. Commandeur, C., Chalumeasu, C., Dessolin, J., and Laguerre, M. Eur. J. Org. Chem. 2007, 3045-3052