High frequency of vitamin B12 deficiency in a Brazilian population

Public Health Nutrition

Volumn 13, Issue 8, 2010, Pages 1191-1197

  Xavier, J M ^a   Costa, F F ^a   Annichino Bizzacchi, J M ^a   Saad, S T O ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Cobalamin deficiency; Electrochemiluminescence immunoassay; Methylmalonic acid; Radioimmunoassay; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; METHYLMALONIC ACID;

ADULT; AGE; AGED; ARTICLE; BLOOD; BRAZIL; CYANOCOBALAMIN DEFICIENCY; HUMAN; IMMUNOASSAY; METHODOLOGY; MIDDLE AGED; PREVALENCE;

ADULT; AGE FACTORS; AGED; BRAZIL; HUMANS; IMMUNOASSAY; METHYLMALONIC ACID; MIDDLE AGED; PREVALENCE; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 77957242128     PISSN: 13689800     EISSN: 14752727     Source Type: Journal    
DOI: 10.1017/S1368980009992205     Document Type: Article

References (13)

1. Hin H, Clarke R, Sherliker P et al. (2006) Clinical relevance of low serum vitamin B12 concentrations in older people: The Banbury B12 study. Age Ageing 35, 416-422.
2. Clarke R, Refsum H, Birks J et al. (2003) Screening for vitamin B-12 and folate deficiency in older persons. Am J Clin Nutr 77, 1241-1247.
3. Cuskelly GJ, Mooney KM & Young IS (2007) Folate and vitamin B12: Friendly or enemy nutrients for the elderly. Proc Nutr Soc 66, 548-558.
4. Masnou H, Domenech E, Navarro-Llavat M et al. (2007) Pernicious anaemia in triplets. A case report and literature review. Gastroenterol Hepatol 30, 580-582.
5. Solomon LR (2005) Cobalamin-responsive disorders in the ambulatory care setting: Unreliability of cobalamin, methylmalonic acid, and homocysteine testing. Blood 105, 978-985.
6. Lewerin C, Matousek M, Steen G et al. (2005) Significant correlations of plasma homocysteine and serum methylmalonic acid with movement and cognitive performance in elderly subjects but no improvement from short-term vitamin therapy: A placebo-controlled randomized study. Am J Clin Nutr 81, 1155-1162.
7. Stabler SP & Allen RH (2004) Vitamin B12 deficiency as a worldwide problem. Annu Rev Nutr 24, 299-326.
8. Clarke R, Sherliker P, Hin H et al. (2007) Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin. Clin Chem 53, 963-970.
9. Raman G, Tatsioni A, Chung M et al. (2007) Heterogeneity and lack of good quality studies limit association between folate, vitamins B-6 and B-12, and cognitive function. J Nutr 137, 1789-1794.
10. Fora MA & Mohammad MA (2005) High frequency of suboptimal serum vitamin B12 level in adults in Jordan. Saudi Med J 26, 1591-1595.
11. VanderJagt DJ, Spelman K, Ambe J et al. (2000) Folate and vitamin B12 status of adolescent girls in northern Nigeria. J Natl Med Assoc 92, 334-340.
12. Green R (2005) Unreliability of current assays to detect cobalamin deficiency: 'nothing gold can stay'. Blood 105, 910.
13. Kumar S, Ghosh K & Das KC (1989) Serum vitamin B12 levels in an Indian population: An evaluation of three assay methods. Med Lab Sci 46, 120-126