Cocaine administration increases CD4/CD8 lymphocyte ratio in peripheral blood despite lymphopenia and elevated corticosterone

International Immunopharmacology

Volumn 10, Issue 10, 2010, Pages 1229-1234

  Jankowski, Maciej M ^a   Ignatowska Jankowska, Bogna ^a   Glac, Wojciech ^a   Swiergiel, Artur H ^a,b  

^a UNIVERSITY OF GDA SK   (Poland)

^b INSTITUTE OF GENETICS AND ANIMAL BREEDING   (Poland)

Author keywords

Cocaine; Immune system; Intravenous; Lymphocyte subset; Peripheral blood; Rat

Indexed keywords

COCAINE; CORTICOSTERONE; GAMMA INTERFERON;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DRUG EFFECT; DRUG RESPONSE; EXPERIMENT; HUMAN; IMMUNOTOXICITY; LEUKOCYTE; LEUKOCYTE COUNT; LOCOMOTION; LYMPHOCYTE COUNT; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTOPENIA; MALE; NATURAL KILLER CELL; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; WISTAR RAT;

ANIMALS; CD4-CD8 RATIO; COCAINE; CORTICOSTERONE; DRUG ADMINISTRATION SCHEDULE; INTERFERON-GAMMA; LYMPHOPENIA; MALE; RATS; RATS, WISTAR; T-LYMPHOCYTES; WEIGHT GAIN;

EID: 77957235665     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.07.003     Document Type: Article

References (45)

1. Prakash A., Das G. Cocaine and the nervous system. Int J Clin Pharmacol Ther Toxicol 1993, 31:575-581.
2. Pillai R., Nair B.S., Watson R.R. AIDS, drugs of abuse and the immune system: a complex immunotoxicological network. Arch Toxicol 1991, 65:609-617.
3. Pacifici R., Di Carlo S., Bacosi A., Zuccaro P. Macrophage functions in drugs of abuse-treated mice. Int J Immunopharmacol 1993, 15:711-716.
4. Pacifici R., Fiaschi A.I., Micheli L., Centini F., Giorgi G., Zuccaro P., et al. Immunosuppression and oxidative stress induced by acute and chronic exposure to cocaine in rat. Int Immunopharmacol 2003, 3:581-592.
5. Pellegrino T.C., Dunn K.L., Bayer B.M. Mechanisms of cocaine-induced decreases in immune cell function. Int Immunopharmacol 2001, 1:665-675.
6. Cabral G.A. Drugs of abuse, immune modulation, and AIDS. J Neuroimmune Pharmacol 2006, 1:280-295.
7. Seligmann M., Pinching A.J., Rosen F.S., Fahey J.L., Khaitov R.M., Klatzmann D., et al. Immunology of human immunodeficiency virus infection and the acquired immunodeficiency syndrome. An update. Ann Intern Med 1987, 107:234-242.
8. Pahwa S., Read J.S., Yin W., Matthews Y., Shearer W., Diaz C., et al. CD4+/CD8+ T cell ratio for diagnosis of HIV-1 infection in infants: Women and Infants Transmission Study. Pediatrics 2008, 122:331-339.
9. Butt F.M., Vaghela V.P., Chindia M.L. Correlation of CD4 counts and CD4/CD8 ratio with HIV-infection associated oral manifestations. East Afr Med J 2007, 84:383-388.
10. Shearer W.T., Pahwa S., Read J.S., Chen J., Wijayawardana S.R., Palumbo P., et al. CD4/CD8 T-cell ratio predicts HIV infection in infants: the National Heart, Lung, and Blood Institute P2C2 Study. J Allergy Clin Immunol 2007, 120:1449-1456.
11. Viso A.T., de Castro Barbosa T., Yamamoto L., Pagliari C., Fernandes E.R., Brasil R.A., et al. Portal CD4+ and CD8+ T lymphocyte correlate to intensity of interface hepatitis in chronic hepatitis C. Rev Inst Med Trop São Paulo 2007, 49:371-378.
12. Hussein M.R., Fathi N.A., El-Din A.M., Hassan H.I., Abdullah F., Al-Hakeem E., et al. Alterations of the CD4(+), CD8 (+) T cell subsets, interleukins-1beta, IL-10, IL-17, tumor necrosis factor-alpha and soluble intercellular adhesion molecule-1 in rheumatoid arthritis and osteoarthritis: preliminary observations. Pathol Oncol Res 2008, 14:321-328.
13. Pichler R., Sfetsos K., Badics B., Gutenbrunner S., Berg J., Auböck J. Lymphocyte imbalance in vitiligo patients indicated by elevated CD4+/CD8+ T-cell ratio. Wien Med Wochenschr 2009, 159:337-341.
14. Di Francesco P., Pica F., Croce C., Favalli C., Tubaro E., Garaci E. Effect of acute or daily cocaine administration on cellular immune response and virus infection in mice. Nat Immun Cell Growth Regul 1990, 9:397-405.
15. Vaz A., Lefkowitz S.S., Lefkowitz D.L. Effects of cocaine on the respiratory burst of murine macrophages. Adv Exp Med Biol 1993, 335:135-142.
16. Phillips D.L., Tebbett I.R., Masten S., Shiverick K.T. Stimulatory effects of cocaine and its metabolites on IM-9 human B-lymphoblastoid cells. Int J Immunopharmacol 1995, 17:57-63.
17. Stanulis E.D., Jordan S.D., Rosecrans J.A., Holsapple M.P. Disruption of Th1/Th2 cytokine balance by cocaine is mediated by corticosterone. Immunopharmacology 1997, 37:25-33.
18. Xu W., Bai F., Tummalapalli C.M., Miller D.D., Middaugh L., Boggan W.O. The interactive effects of cocaine/gender on immune function in mice. An observation of in vivo acute cocaine exposure. Int J Immunopharmacol 1997, 19:333-340.
19. Gan X., Zhang L., Newton T., Chang S.L., Ling W., Kermani V., et al. Cocaine infusion increases interferon-gamma and decreases interleukin-10 in cocaine-dependent subjects. Clin Immunol Immunopathol 1998, 89:181-190.
20. Mukunda B.N., Callahan J.M., Hobbs M.S., West B.C. Cocaine inhibits human neutrophil phagocytosis and phagolysosomal acidification in vitro. Immunopharmacol Immunotoxicol 2000, 22:373-386.
21. Colombo L.L., López M.C., Chen G.J., Watson R.R. Effect of short-term cocaine administration on the immune system of young and old C57BL/6 female mice. Immunopharmacol Immunotoxicol 1999, 21:755-769.
22. Irwin M.R., Olmos L., Wang M., Valladares E.M., Motivala S.J., Fong T., et al. Cocaine dependence and acute cocaine induce decreases of monocyte proinflammatory cytokine expression across the diurnal period: autonomic mechanisms. J Pharmacol Exp Ther 2007, 320:507-515.
23. Fischman M.W., Schuster C.R. Cocaine self-administration in humans. Fed Proc 1982, 41:241-246.
24. Fischman M.W., Schuster C.R., Javaid J., Hatano Y., Davis J. Acute tolerance development to the cardiovascular and subjective effects of cocaine. J Pharmacol Exp Ther 1985, 235:677-682.
25. Siegel R.K. New patterns of cocaine use: changing doses and routes. NIDA Res Monogr 1985, 61:204-220.
26. Zhou Y., Spangler R., Schlussman S.D., Ho A., Kreek M.J. Alterations in hypothalamic-pituitary-adrenal axis activity and in levels of proopiomelanocortin and corticotropin-releasing hormone-receptor 1 mRNAs in the pituitary and hypothalamus of the rat during chronic 'binge' cocaine and withdrawal. Brain Res 2003, 964:187-199.
27. Morishima H.O., Whittington R.A., Iso A., Cooper T.B. The comparative toxicity of cocaine and its metabolites in conscious rats. Anesthesiology 1999, 90:1684-1690.
28. Hutchaleelaha A., Sukbuntherng J., Mayersohn M. Simple apparatus for serial blood sampling in rodents permitting simultaneous measurement of locomotor activity as illustrated with cocaine. J Pharmacol Toxicol Meth 1997, 37:9-14.
29. Ruiz P., Berho M., Steele B.W., Hao L. Peripheral human T lymphocyte maintenance of immune functional capacity and phenotypic characteristics following in vivo cocaine exposure. Clin Immunol Immunopathol 1998, 88:271-276.
30. Chao C., Jacobson L.P., Tashkin D., Martínez-Maza O., Roth M.D., Margolick J.B., et al. Recreational drug use and T lymphocyte subpopulations in HIV-uninfected and HIV-infected men. Drug Alcohol Depend 2008, 94:165-171.
31. Calogero A.E., Gallucci W.T., Kling M.A., Chrousos G.P., Gold P.W. Cocaine stimulates rat hypothalamic corticotropin-releasing hormone secretion in vitro. Brain Res 1989, 505:7-11.
32. Borowsky B., Kuhn C.M. Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation. J Pharmacol Exp Ther 1991, 256:204-210.
33. Levy A.D., Li Q.A., Kerr J.E., Rittenhouse P.A., Milonas G., Cabrera T.M., Battaglia G. Alvarez Sanz MC, Van de Kar LD. Cocaine-induced elevation of plasma adrenocorticotropin hormone and corticosterone is mediated by serotonergic neurons. J Pharmacol Exp Ther 1991, 259:495-500.
34. Sarnyai Z., Bíró E., Telegdy G. Cocaine-induced elevation of plasma corticosterone is mediated by different neurotransmitter systems in rats. Pharmacol Biochem Behav 1993, 45:209-214.
35. Baumann M.H., Gendron T.M., Becketts K.M., Henningfield J.E., Gorelick D.A., Rothman R.B. Effects of intravenous cocaine on plasma cortisol and prolactin in human cocaine abusers. Biol Psychiatry 1995, 38:751-755.
36. Bayer B.M., Mulroney S.E., Hernandez M.C., Ding X.Z. Acute infusions of cocaine result in time- and dose-dependent effects on lymphocyte responses and corticosterone secretion in rats. Immunopharmacology 1995, 29:19-28.
37. Ader R., Felten D., Cohen N. Interactions between the brain and the immune system. Annu Rev Pharmacol Toxicol 1990, 30:561-602.
38. Madden K.S., Felten D.L. Experimental basis for neural-immune interactions. Physiol Rev 1995, 75:77-106.
39. Maher S.G., Romero-Weaver A.L., Scarzello A.J., Gamero A.M. Interferon: cellular executioner or white knight?. Curr Med Chem 2007, 14:1279-1289.
40. Klein T.W., Matsui K., Newton C.A., Young J., Widen R.E., Friedman H. Cocaine suppresses proliferation of phytohemagglutinin-activated human peripheral blood T-cells. Int J Immunopharmacol 1993, 15:77-86.
41. Lopez M.C., Watson R.R. Effect of cocaine and murine AIDS on lamina propria T and B cells in normal mice. Life Sci 1994, 54:147-151.
42. Duncan R., Shapshak P., Page J.B., Chiappelli F., McCoy C.B., Messiah S.E. Crack cocaine: effect modifier of RNA viral load and CD4 count in HIV infected African American women. Front Biosci 2007, 12:1488-1495.
43. Patterson B.K., Landay A., Siegel J.N., Flener Z., Pessis D., Chaviano A., et al. Susceptibility to human immunodeficiency virus-1 infection of human foreskin and cervical tissue grown in explant culture. Am J Pathol 2002, 161:867-873.
44. Koning F.A., Otto S.A., Hazenberg M.D., Dekker L., Prins M., Miedema F., et al. Low-level CD4+ T cell activation is associated with low susceptibility to HIV-1 infection. J Immunol 2005, 175:6117-6122.
45. Bégaud E., Chartier L., Marechal V., Ipero J., Léal J., Versmisse P., et al. Reduced CD4 T cell activation and in vitro susceptibility to HIV-1 infection in exposed uninfected Central Africans. Retrovirology 2006, 3:35.