HPLC-MS determination of Acrolein and Acetone generated from 13c3 -labeled Glycerol added to cigarette tobacco using two machine-smoking regimes

Beitrage zur Tabakforschung International/ Contributions to Tobacco Research

Volumn 24, Issue 2, 2010, Pages 48-57

  Yip, Shiu Hang Henry ^a   Taylor, Larry T ^a   Ashraf Khorassani, Mehdi ^a   Yu, Jianxin ^a   Borgerding, Michael F ^b   Coleman III, William M ^b   Bodnar, Joy A ^b  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b R J REYNOLDS TOBACCO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTIANA TABACUM;

EID: 77957226727     PISSN: 0173783X     EISSN: 16129237     Source Type: Journal    
DOI: 10.2478/cttr-2013-0881     Document Type: Article

References (17)

1. Stein, Y. S., M. J. Antal Jr, and M. Jones Jr: A Study of the Gas-Phase Pyrolysis of Glycerol; J. Anal. Appl. Pyrol.: 4 (1983) 283-296.
2. Canada Government Tobacco Act: Tobacco Reporting Regulations, SOR/2000-273. Registration June 26, 2000. Part 3 - Emissions from Designated Tobacco Products. Available from (Accessed July 2010): < http://www.hc-sc.gc.ca/hl-vs/pubs/tobac-tabac/tirrft/emissions-eng.php> or through Health Canada, Tobacco Control Programme, P.L. 3507A1, Ottawa, Canada, K1A 0K9.
3. Canada Government Tobacco Act: Tobacco Reporting Regulations, SOR/2000-273. Registration June 26, 2000. Schedule 2: Official Methods for Collection of Emission Data on Mainstream Smoke. Available from (accessed July 2010): or through Health Canada, Tobacco Control Programme, P.L. 3507A1, Ottawa, Canada, K1A 0K9.
4. Counts, M.E., M.J. Morton, S.W. Laffoon, R.H. Cox, and P.J. Lipowicz: Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions; Regul. Toxicol. Pharmacol. 41 (2005) 185-227.
5. Chung, H.L., D.S. Moore, and J.C. Aldridge: Pyrolyzates of glycerin; February, 1987, see www.rjrtdocs.com 512077486
6. Baker, R.R. and L.J. Bishop: The pyrolysis of tobacco ingredients; J. Anal. Appl. Pyrolysis 71 (2004) 223-311.
7. Gori, G.B. (Editor): Report No. 3. Toward less hazardous cigarettes. The third set of experimental cigarettes; DHEW Publ. No. (NIH) 77-1280 (1977).
8. Blake, C.: The effect of the humectants glycerol and propylene glycol on mainstream and sidestream smoke deliveries of acrolein, formaldehyde, acetaldehyde, acetone and propionaldehyde; February, 1987, see (Accessed July 2010): http://legacy.library.ucsf.edu/tid/jvl37e00/pdf?searc h=%222029135129%22.
9. Baker, R.R., J.R. Pereira da Silva, and G. Smith: The effect of tobacco ingredients on smoke chemistry. Part II: Casing ingredients; Food Chem. Toxicol. 42S (2004) S39-S52.
10. Pillsbury, H.C., C.C. Bright, K.J. O'Connor, and F.W. Irish: Tar and nicotine in cigarette smoke; J. Assoc. Off. Anal. Chem. 52 (1969) 458-462.
11. Stevens, N.A. and M.F. Borgerding: GC-AED studies of nicotine fate in a burning cigarette; Anal. Chem. 71 (1999) 2179-2185.
12. Rodgman, A. and T.A. Perfetti: The Chemical Components of Tobacco and Tobacco Smoke; CRC Press. Boca Raton, FL, 2009.
13. Green, C.R. and A. Rodgman: The Tobacco Chemists' Research Conference: A half century forum for advances in analytical methodology of tobacco and its products; Rec. Adv. Tob. Sci. 22 (1996) 131-304.
14. Borgerding, M. and H. Klus: Analysis of complex mixtures - Cigarette smoke; Exp. Toxicol. Pathol. 57 (2005) 43-73.
15. Dong, J.Z. and S.C. Moldoveanu: Gas chromatography-mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2, 4-dinitrophenylhydrazine; J. Chromatogr. A 1027 (2003) 25-35.
16. Wang, T.L., H.W. Tong, X.Y. Yan, L.Q. Sheng, J. Yang and S.M. Liu: Determination of volatile carbonyl compounds in cigarette smoke by LC-DAD; Chromatographia 62 (2005) 631-636.
17. Stotesbury, S.J., L.J. Willoughby, and A. Couch: Pyrolysis of Cigarette Ingredients Labeled with Stable Isotopes; Beitr. Tabakforsch. Int. 19 (2000) 55-64.