Osteoblastic differentiation of human and equine adult bone marrow-derived mesenchymal stem cells when BMP-2 or BMP-7 homodimer genetic modification is compared to BMP-2/7 heterodimer genetic modification in the presence and absence of dexamethasone

Journal of Orthopaedic Research

Volumn 28, Issue 10, 2010, Pages 1330-1337

  Carpenter, Ryan S ^a   Goodrich, Laurie R ^a   Frisbie, David D ^a   Kisiday, John D ^a   Carbone, Beth ^a   McIlwraith, C Wayne ^a   Centeno, Christopher J ^b   Hidaka, Chisa ^c  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b Centeno Schultz Clinic   (United States)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

BMP 2; BMP 7; Bone marrow derived mesenchymal stem cells; Genetic modification; Heterodimer

Indexed keywords

ADENOVIRUS VECTOR; ALKALINE PHOSPHATASE; DEXAMETHASONE; OSTEOCALCIN; OSTEONECTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT OSTEOGENIC PROTEIN 1; TRANSCRIPTION FACTOR RUNX2; ANTIINFLAMMATORY AGENT; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; OSTEOGENIC PROTEIN 1;

ADULT; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; DNA MODIFICATION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME RELEASE; FEMALE; GENE TRANSFER; HORSE; HUMAN; HUMAN CELL; ILIAC CREST; MALE; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ANIMAL MODEL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETIC TRANSDUCTION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM;

ADULT; ALKALINE PHOSPHATASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 7; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DEXAMETHASONE; FEMALE; HORSES; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MODELS, ANIMAL; OSTEOBLASTS; OSTEOCALCIN; OSTEONECTIN; TRANSDUCTION, GENETIC;

EID: 77957190145     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21126     Document Type: Article

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