A novel two-chain IGF-II-derived peptide from purified β-cell granules

Growth Hormone and IGF Research

Volumn 20, Issue 5, 2010, Pages 360-366

  Buchanan, Christina M ^a,b   Phillips, Anthony R J ^a,b,c   Cooper, Garth J S ^a,c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b Faculty of Medical and Health Sciences   (New Zealand)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Beta cell; Cell line; Cultured cells; Insulin like growth factor II; Isoform; Metabolism; Secretory granule

Indexed keywords

AMINE; GLUCOSE; GLYCOGEN; INSULIN; PEPTIDE; SOMATOMEDIN B; UNCLASSIFIED DRUG; VESICULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLYCOGEN SYNTHESIS; MOLECULAR WEIGHT; MOUSE; MUSCLE EXCITATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SECRETORY GRANULE; SOLEUS MUSCLE;

ANIMALS; CELL LINE; GLYCOGEN; HUMANS; INSULIN-LIKE GROWTH FACTOR II; INSULIN-SECRETING CELLS; MALE; MICE; MUSCLE, SKELETAL; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SECRETORY VESICLES;

EID: 77957162882     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2010.06.003     Document Type: Article

References (46)

1. Randhawa R., Cohen P. The role of the insulin-like growth factor system in prenatal growth. Mol. Genet. Metab. 2005, 86:84-90.
2. Acerini C.L., Clayton K.L., Hintz R., Baker B., Watts A., Holly J.M., Dunger D.B. Serum insulin-like growth factor II levels in normal adolescents and those with insulin dependent diabetes mellitus. Clin. Endocrinol. (Oxf.) 1996, 45:13-19.
3. Qiu Q., Jiang J.Y., Bell M., Tsang B.K., Gruslin A. Activation of endoproteolytic processing of insulin-like growth factor-II in fetal, early postnatal, and pregnant rats and persistence of circulating levels in postnatal life. Endocrinology 2007, 148:4803-4811.
4. Holly J.M. The IGF-II enigma. Growth Horm. IGF Res. 1998, 8:183-184.
5. Dupont J., Pierre A., Froment P., Moreau C. The insulin-like growth factor axis in cell cycle progression. Horm. Metab. Res. 2003, 35:740-750.
6. Gammeltoft S. Insulin-like growth factors and insulin: gene expression, receptors and biological actions. Peptide Hormones as Prohormones 1989, 176-210. Ellis Horwood Limited Chichester. J. Martinez (Ed.).
7. Guest P., Arden S., Bennet D., Clark A., Rutherford N., Hutton J. The post-translational processing and intracellular sorting of PC2 in the islets of langerhans. J. Biol. Chem. 1992, 267:222401-222406.
8. Rotwein P. Structure, evolution, expression and regulation of insulin-like growth factors I and II. Growth Factors 1991, 5:3-18.
9. Duguay S.J., Jin Y., Stein J., Duguay A.N., Gardner P., Steiner D.F. Post-translational processing of the insulin-like growth factor-2 precursor. Analysis of O-glycosylation and endoproteolysis. J. Biol. Chem. 1998, 273:18443-18451.
10. Zumstein P., Luthi C., Humbel R. Amino acid sequence of a variant pro-form of insulin-like growth factor II. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:3169-3172.
11. Bell G.I., Gerhard D.S., Fong N.M., Sanchez-Pescador R., Rall L.B. Isolation of the human insulin-like growth factor genes: insulin-like growth factor II and insulin genes are contiguous. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:6450-6454.
12. Maake C., Reinecke M. Immunohistochemical localization of insulin-like growth factor 1 and 2 in the endocrine pancreas of rat, dog, and man, and their coexistence with classical islet hormones. Cell Tissue Res. 1993, 273:249-259.
13. Hoog A., Grimelius L., Falkmer S., Sara V. A high-molecular weight IGF-2 immunoreactive peptide (pro-IGF-2?) in the insulin cells of the islets of Langerhans in pancreas of man and rat. Regul. Peptides 1993, 47:275-283.
14. Reinecke M., Weimar E., Maake C., Drakenberg K., Falkmer S., Sara V.R. IGF-2-like peptides are present in insulin cells of the elasmobranchian endocrine pancreas: an immunohistochemical and chromatographic study. Histochem. 1994, 102:365-371.
15. Reinecke M., Broger I., Brun R., Zapf J., Maake C. Immunohistochemical localization of insulin-like growth factor I and II in the endocrine pancreas of birds, reptiles, and amphibia. Gen. Comp. Endocrinol. 1995, 100:385-396.
16. Straczek J., Heulin M., Chenut A., Lasbennes A., Geschier C., Belleville F., Nabet P. Purification and characterisation of three molecular weight forms of insulin-like growth factor II from human Cohn paste IV. J. Chromatog. 1990, 532:237-248.
17. Mohan S. A simple and efficient scheme for the purification of insulin-like growth factor II from human bone matrix extract. Growth Factors 1990, 2:267-271.
18. Valenzano K.J., Heath-Monnig E., Tollefsen S.E., Lake M., Lobel P. Biophysical and biological properties of naturally occurring high molecular weight insulin-like growth factor II variants. J. Biol. Chem. 1997, 272:4804-4813.
19. Hudgins W., Hampton B., Burgess W., Perdue J. The identification of O-glycosylated precursors of insulin-like growth factor II. J. Biol. Chem. 1992, 267:8153-8160.
20. Daughaday W.H., Trivedi B., Baxter R.C. Serum "big insulin-like growth factor II" from patients with tumor hypoglycemia lacks normal E-domain O-linked glycosylation, a possible determinant of normal propeptide processing. Proc. Natl. Acad. Sci. U. S. A. 1993, 90:5823-5827.
21. Hoog A., Hu W., Abdel-Halim S.M., Falkmer S., Qing L., Grimelius L. Ultrastructural localization of insulin-like growth factor-2 (IGF-2) to the secretory granules of insulin cells: a study in normal and diabetic (GK) rats. Ultrastruct. Pathol. 1997, 21:457-466.
22. Buchanan C.M., Phillips A.R., Cooper G.J. Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insulin secretion. Biochem. J. 2001, 360:431-439.
23. Knaack D., Fiore D., Surana M., Leiser M., Laurance M., Fusco-DeMane D., Hegre O., Fleischer N., Efrat S. Clonal insulinoma cell line that stably maintains correct glucose responsiveness. Diabetes 1994, 43:1413-1417.
24. Hunter W., Greenwood F. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 1962, 194:495-496.
25. Cooper G., Willis A., Clark A., Turner R., Sim R., Reid K. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc. Natl. Acad. Sci. U. S. A. 1987, 84:8628-8632.
26. Buchanan C.M., Malik A.S., Cooper G.J. Direct visualisation of peptide hormones in cultured pancreatic islet alpha- and beta-cells by intact-cell mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21:3452-3458.
27. Cooper G., Leighton B., Dimitriadis G., Parry-Billings M., Kowalchuk J., Howland K., Rothbard J., Willis A., Reid K. Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal musclee. Proc. Natl. Acad. Sci. U. S. A. 1988, 85:7763-7766.
28. Yang Y.W.-H., Rechler M., Nissley S., Coligan J. Biosynthesis of rat insulin-like growth factor II. II. Localisation of mature rat insulin-like growth factor II (7484daltons) to the amino terminus of the 20-kilodalton biosynthetic precursor by radiosequence analysis. J. Biol. Chem. 1985, 260:2578-2582.
29. Barr P. Mammalian subtilisins: the long-sought dibasic processing endoproteases. Cell 1991, 66:1-3.
30. Guo Q., Manolopoulou M., Bian Y., Schilling A.B., Tang W.J. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J. Mol. Biol. 2009, 430-443.
31. Jansen M., van Schaik F.M., van Tol H., Van den Brande J.L., Sussenbach J.S. Nucleotide sequences of cDNAs encoding precursors of human insulin-like growth factor II (IGF-II) and an IGF-II variant. FEBS Lett. 1985, 179:243-246.
32. Hampton B., Burgess W., Marshak D., Cullen K., Perdue J. Purification and characterisation of an insulin-like growth factor II variant from human plasma. J. Biol. Chem. 1989, 264:19155-19160.
33. Gowan L., Hampton B., Hill D., Schlueter R., Perdue J. Purification and characterization of a unique high molecular weight form of insulin-like growth factor II. Endocrinol. 1987, 121:449.
34. Haselbacher G., Humbel R. Evidence for two species of insulin-like growth factor II (IGF II and "Big" IGF II) in human spinal fluid. Endocrinol. 1982, 110:1822-1824.
35. Haselbacher G., Schwab M., Pasi A., Humbel R. Insulin-like growth factor II (IGF II) in human brain: regional distribution of IGF II and of higher molecular mass forms. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:2153-2157.
36. Daughaday W., Emanuele M., Brooks M., Barbato A., Kapadia M., Rotwein P. Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycaemia. New Eng. J. Med. 1988, 319:1434.
37. Shapiro E., Bell G., Polansky K., Rubenstein A., Kew M., Tager H. Tumour hypoglycemia: relationship to high molecular weight insulin-like growth factor-II. J. Clin. Inv. 1990, 85:1672.
38. Jansen J., Buul-offers S.V., Hoogerbrugge C., Brande J.V.D. Effects of a single cleavage in insulin-like growth factors I and II on binding to receptors, carrier proteins and antibodies. Biochem. J. 1990, 266:513-520.
39. Zarn J.A., Luthi C., Giger R.J., Sigrist A., Humbel R.E. A mutant of human insulin-like growth factor II (IGF II) with the processing sites of proinsulin. Expression and binding studies of processed IGF II. Eur. J. Biochem. 1992, 210:665-669.
40. Frystyk J., Skjaerbaek C., Dinesin B., Orskov H. Free insulin-like growth factors (IGF-I and IGF-II) in human serum. FEBS Lett. 1994, 348:185-191.
41. Frystyk J., Skjaerbaek C., Vestbo E., Fisker S., Orskov H. Circulating levels of free insulin-like growth factors in obese subjects: the impact of type 2 diabetes. Diabetes Metab. Res. Rev. 1999, 15:314-322.
42. Blundell T.L., Humbel R.E. Hormone families: pancreatic hormones and homologous growth factors. Nature 1980, 287:781-787.
43. A. Ferreira 1998 Purification and partial characterisation of mouse insulin I and II. In. BSc(Hons) Thesis, Auckland: University of Auckland.
44. Zierath J.R., Bang P., Galuska D., Hall K., Wallberg-Henriksson H. Insulin-like growth factor II stimulates glucose transport in human skeletal muscle. FEBS Lett 1992, 307:379-382.
45. Burguera B., Elton C.W., Caro J.F., Tapscott E.B., Pories W.J., Dimarchi R., Sakano K., Dohm G.L. Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor. Biochem. J. 1994, 300(Pt 3):781-785.
46. Yu K.T., Czech M.P. The type I insulin-like growth factor receptor mediates the rapid effects of multiplication-stimulating activity on membrane transport systems in rat soleus muscle. J. Biol. Chem. 1984, 259:3090-3095.