Myostatin null mice respond differently to dietary-induced and genetic obesity

Animal Science Journal

Volumn 81, Issue 5, 2010, Pages 586-593

  Dilger, Anna C ^a   Spurlock, Michael E ^a   Grant, Alan L ^a   Gerrard, David E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Leptin; Mice; Muscle; Myostatin; Obesity

Indexed keywords

MSTN PROTEIN, MOUSE; MYOSTATIN;

ANIMAL; ARTICLE; DIET; FAT INTAKE; GENETICS; MOUSE; MOUSE MUTANT; OBESITY;

ANIMALS; DIET; DIETARY FATS; MICE; MICE, KNOCKOUT; MYOSTATIN; OBESITY;

MUS;

EID: 77957142801     PISSN: 13443941     EISSN: 17400929     Source Type: Journal    
DOI: 10.1111/j.1740-0929.2010.00776.x     Document Type: Article

References (31)

1. Allen DL, Cleary AS, Speaker KJ, Lindsay SF, Uyenishi J, Reed JM, Madden MC, Mehan RS. Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice. American Journal of Physiology- Endocrinology and Metabolism 2008, 294:E918-E927.
2. Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, More KJ, Breitbart RE. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Developmental Cell 2002, 2:497-503.
3. Chua SC, Chung WK, Wu-Peng XS, Zhang Y, Liu SM, Tartaglia L, Leibel RL. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science 1996, 271:994-996.
4. Diez JJ, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. European Journal of Endocrinology 2003, 148:293-300.
5. Feldman BJ, Streeper RS, Farese RV, Yamamoto KR. Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:15675-15680.
6. Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proceedings of the National Academy of Sciences of the United States of America 2001, 98:2005-2010.
7. Grobet L, Poncelet D, Royo LJ, Brouwers B, Pirottin D, Michaux C, Menissier F, Zanotti M, Dunner S, Georges M. Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle. Mammalian Genome 1998, 9:210-213.
8. Grobet L, Royo Martin LJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Menissier F, Massabanda J. A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nature Genetics 1997, 17:71-74.
9. Hamilton BS, Paglia D, Kwan AY, Deitel M. Increased obese mRNA expression in omental fat cells from massively obese humans. Nature Medicine 1995, 1:953-956.
10. Hamrick MW, Pennington C, Webb CN, Isales CM. Resistance to body fat gain in 'double-muscled' mice fed a high-fat diet. International Journal of Obesity 2006, 30:868-870.
11. Hollenberg CH, Vost A, Patten RL. Regulation of adipose mass: control of fat cell development and lipid content. Recent Progress in Hormone Research 1970, 26:463-503.
12. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor a: direct role in obesity-linked insulin resistance. Science 1993, 259:87-91.
13. Johnson PR, Hirsch J. Cellularity of adipose depots in six strains of genetically obese mice. Journal of Lipid Research 1972, 13:2-11.
14. Kambadur R, Sharma M, Smith TP, Bass JJ. Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Research 1997, 7:910-916.
15. Lee SJ, McPherron AC. Myostatin and the control of skeletal muscle mass. Current Opinion in Genetics and Development 1999, 9:604-607.
16. Leshner AI, Litwin VA, Squibb RL. A simple method for carcass analysis. Physiology and Behavior 1972, 9:281-282.
17. Levin N, Nelson C, Gurney A, Vandlen R, De Sauvage F. Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:1726-1730.
18. Lin J, Arnold HB, Della-Fera MA, Azain MJ, Hartzell DL, Baile CA. Myostatin Knockout in Mice Increases Myogenesis and Decreases Adipogenesis. Biochemical and Biophysical Research Communications 2002, 291:701-706.
19. Margetic S, Gazzola C, Pegg GG, Hill RA. Leptin: a review of its peripheral actions and interactions. International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity 2002, 26:1407-1433.
20. McMeekan CP. Growth and development in the pig, with special reference to carcass quality characteristics. Journal of Animal Science 1940, 30:276-345.
21. McPherron AC, Lee SJ. Double muscling in cattle due to mutations in the myostatin gene. Proceedings of the National Academy of Sciences of the United States of America 1997, 94:12457-12461.
22. McPherron AC, Lee SJ. Suppression of body fat accumulation in myostatin-deficient mice. Journal of Clinical Investigation 2002, 109:595-601.
23. McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 1997, 387:83-90.
24. Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA. A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genetics 2007, 3:e79.
25. Schuelke M, Wagner KR, Stolz LE, Hubner C, Riebel T, Komen W, Braun T, Tobin JF, Lee SJ. Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child. New England Journal of Medicine 2004, 350:2682-2688.
26. West DB, York B. Dietary fat, genetic predisposition, and obesity: lessons from animal models. American Journal of Clinical Nutrition 1998, 67:505S-512S.
27. Woods SC, Seeley RJ, Rushing PA, D'Alessio D, Tso P. A controlled high-fat diet induces an obese syndrome in rats. Journal of Nutrition 2003, 133:1081-1087.
28. Yang J, Zhao B. Postnatal expression of myostatin propeptide cDNA maintained high muscle growth and normal adipose tissue mass in transgenic mice fed a high-fat diet. Molecular Reproduction and Development 2006, 73:462-469.
29. Yen TT, Gill AM, Frigeri LG, Barsh GS, Wolff GL. Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene. FASEB Journal 1994, 8:479-488.
30. Zhang Y, Proenca R, Maffel M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372:425-432.
31. Zhao B, Wall RJ, Yang J. Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance. Biochemical and Biophysical Research Communications 2005, 337:248-255.