Insulin facilitates repetitive spike firing in rat insular cortex via phosphoinositide 3-kinase but not mitogen activated protein kinase cascade

Neuroscience

Volumn 170, Issue 4, 2010, Pages 1199-1208

  Takei, H ^a   Fujita, S ^a   Shirakawa, T ^a   Koshikawa, N ^a   Kobayashi, M ^a,b  

^a NIHON UNIVERSITY   (Japan)

^b RIKEN   (Japan)

Author keywords

Action potential; Insular cortex; Neocortex; Protein kinase; Second messenger; Spike

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DEGUELIN; INSULIN; LAVENDUSTIN A; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ACTION POTENTIAL; AFTERHYPERPOLARIZATION; AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; ELECTRODE; FEMALE; FREQUENCY MODULATION; HISTOLOGY; INSULA; MALE; MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SPIKE;

ACTION POTENTIALS; ANIMALS; CEREBRAL CORTEX; FEMALE; INSULIN; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR;

EID: 77957128154     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.07.061     Document Type: Article

References (29)

1. Allen G.V., Saper C.B., Hurley K.M., Cechetto D.F. Organization of visceral and limbic connections in the insular cortex of the rat. J Comp Neurol 1991, 311:1-16.
2. Avruch J., Khokhlatchev A., Kyriakis J.M., Luo Z., Tzivion G., Vavvas D., Zhang X.F. Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade. Recent Prog Horm Res 2001, 56:127-155.
3. Banks W.A., Kastin A.J., Huang W., Jaspan J.B., Maness L.M. Leptin enters the brain by a saturable system independent of insulin. Peptides 1996, 17:305-311.
4. Cantrell D.A. Phosphoinositide 3-kinase signalling pathways. J Cell Sci 2001, 114:1439-1445.
5. Foehring R.C., Schwindt P.C., Crill W.E. Norepinephrine selectively reduces slow Ca2+- and Na+-mediated K+ currents in cat neocortical neurons. J Neurophysiol 1989, 61:245-256.
6. Giza B.K., Scott T.R. Intravenous insulin infusions in rats decrease gustatory-evoked responses to sugars. Am J Physiol 1987, 252:R994-R1002.
7. Havrankova J., Schmechel D., Roth J., Brownstein M. Identification of insulin in rat brain. Proc Natl Acad Sci U S A 1978, 75:5737-5741.
8. Kobayashi M. Differential regulation of synaptic transmission by adrenergic agonists via protein kinase A and protein kinase C in layer V pyramidal neurons of rat cerebral cortex. Neuroscience 2007, 146:1772-1784.
9. Kobayashi M., Sasabe T., Shiohama Y., Koshikawa N. Activation of alpha1-adrenoceptors increases firing frequency through protein kinase C in pyramidal neurons of rat visual cortex. Neurosci Lett 2008, 430:175-180.
10. McCormick D.A., Wang Z., Huguenard J. Neurotransmitter control of neocortical neuronal activity and excitability. Cereb Cortex 1993, 3:387-398.
11. McCormick D.A., Williamson A. Convergence and divergence of neurotransmitter action in human cerebral cortex. Proc Natl Acad Sci U S A 1989, 86:8098-8102.
12. Mirshamsi S., Laidlaw H.A., Ning K., Anderson E., Burgess L.A., Gray A., Sutherland C., Ashford M.L. Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation. BMC Neurosci 2004, 5:54.
13. Naqvi N.H., Bechara A. The hidden island of addiction: the insula. Trends Neurosci 2009, 32:56-67.
14. Niswender K.D., Schwartz M.W. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front Neuroendocrinol 2003, 24:1-10.
15. O'Malley D., Harvey J. Insulin activates native and recombinant large conductance Ca2+-activated potassium channels via a mitogen-activated protein kinase-dependent process. Mol Pharmacol 2004, 65:1352-1363.
16. O'Malley D., Shanley L.J., Harvey J. Insulin inhibits rat hippocampal neurones via activation of ATP-sensitive K+ and large conductance Ca2+-activated K+ channels. Neuropharmacology 2003, 44:855-863.
17. Plum L., Schubert M., Brüning J.C. The role of insulin receptor signaling in the brain. Trends Endocrinol Metab 2005, 16:59-65.
18. Schulingkamp R.J., Pagano T.C., Hung D., Raffa R.B. Insulin receptors and insulin action in the brain: review and clinical implications. Neurosci Biobehav Rev 2000, 24:855-872.
19. Schwindt P.C., Spain W.J., Crill W.E. Effects of intracellular calcium chelation on voltage-dependent and calcium-dependent currents in cat neocortical neurons. Neuroscience 1992, 47:571-578.
20. Shepherd P.R., Withers D.J., Siddle K. Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem J 1998, 333:471-490. Erratum in: Biochem J (1998) 335:711.
21. Spanswick D., Smith M.A., Groppi V.E., Logan S.D., Ashford M.L. Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature 1997, 390:521-525.
22. Spanswick D., Smith M.A., Mirshamsi S., Routh V.H., Ashford M.L. Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nat Neurosci 2000, 3:757-758.
23. van der Heide L.P., Kamal A., Artola A., Gispen W.H., Ramakers G.M. Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-D-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner. J Neurochem 2005, 94:1158-1166.
24. van der Heide L.P., Ramakers G.M., Smidt M.P. Insulin signaling in the central nervous system: learning to survive. Prog Neurobiol 2006, 79:205-221.
25. Wan Q., Xiong Z.G., Man H.Y., Ackerley C.A., Braunton J., Lu W.Y., Becker L.E., MacDonald J.F., Wang Y.T. Recruitment of functional GABAA receptors to postsynaptic domains by insulin. Nature 1997, 388:686-690.
26. Werther G.A., Hogg A., Oldfield B.J., McKinley M.J., Figdor R., Allen A.M., Mendelsohn F.A. Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry. Endocrinology 1987, 121:1562-1570.
27. White M.F. The insulin signalling system and the IRS proteins. Diabetologia 1997, 40:S2-S17.
28. Williams D.B. A novel, rapid, inhibitory effect of insulin on α1β2γ2s γ-aminobutyric acid type A receptors. Neurosci Lett 2008, 443:27-31.
29. Yamamoto T. A neural model for taste aversion learning. Olfaction and taste XI 1994, 471-474. Springer-Verlag, Tokyo. K. Kurihara, N. Suzuki, H. Ogawa (Eds.).