Adrenal insufficiency in hemodynamically unstable neonatesafter open-heart surgery

Congenital Heart Disease

Volumn 5, Issue 5, 2010, Pages 422-429

  Garcia, Xiomara ^a,b   Bhutta, Adnan T ^a,b   Dyamenahalli, Umesh ^a   Imamura, Michiaki ^c   Jaquiss, Robert D B ^c   Prodhan, Parthak ^a,b  

^a Critical Care Medicine   (United States)

^b Pediatric Cardiology   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

ACTH Stimulation test; Adrenal Insufficiency; Hemodynamic Instability; Neonates; Open Heart Surgery; Post Operative

Indexed keywords

ADRENALIN; DOPAMINE; HYDROCORTISONE; MILRINONE; NORADRENALIN; TETRACOSACTIDE;

ADRENAL INSUFFICIENCY; ANOMALOUS LEFT CORONARY ARTERY FROM PULMONARY ARTERY; AORTA COARCTATION; ARTERIAL PRESSURE; ARTERY MALFORMATION; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CORTICOTROPIN TEST; FALLOT TETRALOGY; FEMALE; GREAT VESSELS TRANSPOSITION; HEART HEMODYNAMICS; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOPLASTIC LEFT HEART SYNDROME; LOW DRUG DOSE; LUNG VEIN DRAINAGE ANOMALY; MALE; NEWBORN; OPEN HEART SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM; TRICUSPID VALVE REPAIR;

ADRENAL CORTEX FUNCTION TESTS; ADRENAL INSUFFICIENCY; ADRENOCORTICOTROPIC HORMONE; ARKANSAS; BIOLOGICAL MARKERS; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; CRITICAL ILLNESS; FEMALE; HEART DEFECTS, CONGENITAL; HEMODYNAMICS; HUMANS; HYDROCORTISONE; INFANT, NEWBORN; MALE; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 77957124898     PISSN: 1747079X     EISSN: 17470803     Source Type: Journal    
DOI: 10.1111/j.1747-0803.2010.00447.x     Document Type: Article

References (37)

1. Christen S, Finckh B, Lykkesfeldt J. Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation. Free Radic Biol Med. 2005, 38:1323-1332.
2. Ando M, Park IS, Wada N. Steroid supplementation: a legitimate pharmacotherapy after neonatal open heart surgery. Ann Thorac Surg. 2005, 80:1672-1678.
3. Hoda MR, El-Achkar H, Schmitz E. Systemic stress hormone response in patients undergoing open heart surgery with or without cardiopulmonary bypass. Ann Thorac Surg. 2006, 82:2179-2186.
4. Zimmerman J. Testing the waters. Pediatr Crit Care Med. 2007, 8:305-307.
5. Marik PE, Pastores SM, Annane D. Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med. 2008, 36:1937-1949.
6. Clark L, Preissig C, Rigby MR, Bowyer F. Endocrine issues in the pediatric intensive care unit. Pediatr Clin North Am. 2008, 55:805-833.
7. Riordan FA, Thomson AP, Ratcliffe JM. Admission cortisol and adrenocorticotrophic hormone levels in children with meningococcal disease: evidence of adrenal insufficiency? Crit Care Med. 1999, 27:2257-2261.
8. Hatherill M, Tibby SM, Hilliard T. Adrenal insufficiency in septic shock. Arch Dis Child. 1999, 80:51-55.
9. Bone M, Diver M, Selby A. Assessment of adrenal function in the initial phase of meningococcal disease. Pediatrics. 2002, 110:563-569.
10. Menon K, Clarson C. Adrenal function in pediatric critical illness. Pediatr Crit Care Med. 2002, 3:112-116.
11. Pizarro CF, Troster EJ, Damaini D. Absolute and relative adrenal insufficiency in children with septic shock. Crit Care Med. 2005, 33:855-859.
12. Langer M, Modi BP, Agus M. Adrenal insufficiency in the critically ill neonate and child. Curr Opin Pediatr. 2006, 18:448-453.
13. Dickerson HA, Chang AC. Steroids and low cardiac output syndrome after cardiac surgery in children. Pediatric Crit Care Med. 2005, 6:495-496.
14. Millar KJ, Thiagarajan RR, Laussen PC. Glucocorticoid therapy for hypotension in the cardiac intensive care unit. Pediatr Cardiol. 2007, 28:176-182.
15. Fernandez EF, Montman R, Watterberg KL. ACTH and cortisol response to critical illness in term and late preterm newborns. J Perinatol. 2008, 28:797-802.
16. Baker CF, Barks JD, Engmann C. Hydrocortisone administration for the treatment of refractory hypotension in critically ill newborns. J Perinatol. 2008, 28:412-419.
17. Subhedar NV, Duffy K, Ibrahim H. Corticosteroids for treating hypotension in preterm infants. Cochrane Database Syst Rev. 2007, 1:CD003662.
18. Shore S, Nelson DP, Pearl JM. Usefulness of corticosteroid therapy in decreasing epinephrine requirements in critically ill infants with congenital heart disease. Am J Cardiol. 2001, 88:591-594.
19. Pittinger TP, Sawin RS. Adrenocortical insufficiency in infants with congenital diaphragmatic hernia: a pilot study. J Pediatr Surg. 2000, 35:223-226.
20. Reschini E, Catania A, Giustina G. Plasma cortisol response to ACTH does not accurately indicate the state of hypothalamic-pituitary-adrenal axis. J Endocrinol Invest. 1982, 5:259-261.
21. Zaloga GP, Marik P. Hypothalamic-pituitary-adrenal insufficiency. Crit Care Clin. 2001, 17:25-41.
22. Oelkers W. The role of high- and low-dose corticotropin tests in the diagnosis of secondary adrenal insufficiency. Eur J Endocrinol. 1998, 139:567-570.
23. Abdu TA, Elhadd TA, Neary R, Clayton RN. Comparison of the low dose short synacthen test (1 microg), the conventional dose short synacthen test (250 microg), and the insulin tolerance test for assessment of the hypothalamo-pituitary-adrenal axis in patients with pituitary disease. J Clin Endocrinol Metab. 1999, 84:838-843.
24. Dimopoulou I, Ilias I, Roussou P. Low dose and non septic critically ill patients. Intensive Care Med. 2002, 28:1168-1171.
25. Tordjman K, Jaffe A, Trostanetsky Y. Low-dose (1-microgram) adrenocorticotrophin (ACTH) stimulation as a screening test for impaired hypothalamo-pituitary-adrenal axis function: sensitivity, specificity and accuracy in comparison with the high-dose (250 microgram) test. Clin Endocrinol. 2000, 82:633-640.
26. Annane D, Sébille V, Troché G. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotrophin. JAMA. 2000, 283:1038-1045.
27. Annane D, Sébille V, Charpentier C. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002, 288:862-871.
28. Annane D, Bellisant E, Bollaert PE. Corticosteroids for severe sepsis and septic shock. BMJ. 2004, 329:480-488.
29. Wernovsky G, Wypij D, Jonas RA. Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants. A comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation. 1995, 92:2226-2235.
30. Jenkins KJ, Gauvreau K. Center-specific differences in mortality: preliminary analyses using the Risk Adjustment in Congenital Heart Surgery (RACHS-1) method. J Thorac Cardiovasc Surg. 2002, 124:97-104.
31. Jenkins KJ, Gauvreau K, Newburger JW. Consensus-based method for risk adjustment for surgery for congenital heart disease. J Thorac Cardiovasc Surg. 2002, 123:110-118.
32. Crowley S, Hindmarsh PC, Holownia P. The use of low doses of ACTH in the investigation of adrenal function in man. J Endocrinol. 1991, 130:75-479.
33. Gajarski RJ, Stefanelli CB, Graziano JN, Kaciroti N, Charpie JR, Vazquez D. Adrenocortical response in infants undergoing cardiac surgery with cardiopulmonary bypass and circulatory arrest. Pediatr Crit Care Med. 2010, 11:44-51.
34. Anand KJS, Hansen DD, Hickey PR. Hormone-metabolic stress responses in neonates undergoing cardiac surgery. Anesthesiology. 1990, 73:661-670.
35. Agus MSD, Jaksic T. Critically low hormone and catecholamine concentrations in the primed extracorporeal life support circuit. ASAIO J. 2004, 50:65-67.
36. Bower AN, Oyen LJ. Interaction between dexamethasone treatment and the corticotropin stimulation test in septic shock. Ann Pharmacother. 2005, 39:335-338.
37. Plumpton KR, Anderson BJ, Beca J. Thyroid hormone and cortisol concentrations after congenital heart surgery in infants younger than 3 months of age. Intensive Care Med. 2010, 36:321-328.