Effects of N-acetyl-cysteine and N-acetyl-cysteine-amide supplementation on in vitro matured porcine oocytes

Reproduction in Domestic Animals

Volumn 45, Issue 5, 2010, Pages 755-759

  Whitaker, B D ^a   Knight, J W ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; DRUG DERIVATIVE; N ACETYLCYSTEINAMIDE; N-ACETYLCYSTEINAMIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMISTRY; CULTURE MEDIUM; DOSE RESPONSE; DRUG EFFECT; EMBRYO CULTURE; EMBRYO DEVELOPMENT; FEMALE; FERTILIZATION IN VITRO; OOCYTE; PHYSIOLOGY; PRENATAL DEVELOPMENT; SWINE;

ACETYLCYSTEINE; ANIMALS; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO CULTURE TECHNIQUES; EMBRYONIC DEVELOPMENT; FEMALE; FERTILIZATION IN VITRO; OOCYTES; SWINE;

SUS;

EID: 77957112790     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2009.01344.x     Document Type: Article

References (28)

1. Abeydeera LR, Day BN. In vitro penetration of pig oocytes in a modified Tris-buffered medium: effect of BSA, caffeine and calcium. Theriogenology 1997, 48:537-544.
2. Abeydeera LR, Wang WH, Cantley TC, Prather RS, Day BN. Presence of beta-mercaptoethanol can increase the glutathione content of pig oocytes matured in vitro and the rate of blastocyst development after in vitro fertilization. Theriogenology 1998, 50:747-756.
3. Agarwal A, Gupta S, Sharma RK. Role of oxidative stress in female reproduction. Reprod Biol Endocrinol 2005, 3:28-48.
4. Ali AA, Bilodeau JF, Sirard MA. Antioxidant requirements for bovine oocytes varies during in vitro maturation, fertilization and development. Theriogenology 2003, 59:939-949.
5. Bedaiwy MA, Falcone T, Mohamed MS, Aleem AA, Sharma RK, Worley SE, Thornton J, Agarwal A. Differential growth of human embryos in vitro: role of reactive oxygen species. Fertil Steril 2004, 82:593-600.
6. Cotgreave I, Moldeus P, Schuppe I. The metabolism of N-acetylcysteine by human endothelial cells. Biochem Pharmacol 1991, 42:13-16.
7. Goto Y, Noda Y, Mori T, Nakano M. Increased generation of reactive oxygen species in embryos cultured in vitro. Free Radic Biol Med 1993, 15:69-75.
8. Grinberg L, Fibach E, Amer J, Atlas D. N-acetylcysteine amide, a novel cell-permeating thiol, restores cellular glutathione and protects human red blood cells from oxidative stress. Free Radic Biol Med 2005, 38:136-145.
9. Guerin P, El Mouatassim S, Menezo Y. Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings. Hum Reprod Update 2001, 7:175-189.
10. Issels RD, Nagele A, Eckert KG, Wilmanns W. Promotion of cystine uptake and its utilization for glutathione biosynthesis induced by cysteamine and N-acetylcysteine. Biochem Pharmacol 1988, 37:881-888.
11. de Matos DG, Furnus CC, Moses DF. Glutathione synthesis during in vitro maturation of bovine oocytes: role of cumulus cells. Biol Reprod 1997, 57:1420-1425.
12. Meier T, Issels RD. Promotion of cyst(e)ine uptake. Methods Enzymol 1995, 252:103-112.
13. Mori T, Amano T, Shimizu H. Roles of gap junctional communication of cumulus cells in cytoplasmic maturation of porcine oocytes cultured in vitro. Biol Reprod 2000, 62:913-919.
14. Nakata K, Kawase M, Ogino S, Kinoshita C, Murata H, Sakaue T, Ogata K, Ohmori S. Effects of age on levels of cysteine, glutathione and related enzyme activities in livers of mice and rats and an attempt to replenish hepatic glutathione levels of mouse with cysteine derivatives. Mech Ageing Dev 1996, 90:195-207.
15. Niemann H, Rath D. Progress in reproductive biotechnology in swine. Theriogenology 2004, 56:1291-1304.
16. Nishikimi A, Mukai J, Yamada M. Nuclear translocation of nuclear factor kappa B in early 1-cell mouse embryos. Biol Reprod 1999, 60:1536-1541.
17. Offen D, Gilgun-Sherki Y, Barhum Y, Benhar M, Grinberg L, Reich R, Melamed E, Atlas D. A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis. J Neurochem 2004, 89:1241-1251.
18. Petters RM, Wells KD. Culture of pig embryos. J Reprod Fertil Suppl 1993, 48:61-73.
19. Sen U, Moshal KS, Singh M, Tyagi N, Tyagi SC. Homocysteine-induced biochemical stress predisposes to cytoskeletal remodeling in stretched endothelial cells. Mol Cell Biochem 2007, 302:133-143.
20. Shao DZ, Lee JJ, Huang WT, Liao JF, Lin MT. Inhibition of nuclear factor-kappa B prevents staphylococcal enterotoxin A-induced fever. Mol Cell Biochem 2004, 262:177-185.
21. Tao Y, Zhou B, Xia G, Wang F, Wu Z, Fu M. Exposure to L-ascorbic acid or a-tocopherol facilitates the development of porcine denuded oocytes from metaphase I to metaphase II and prevents cumulus cells from fragmentation. Reprod Domest Anim 2004, 39:52-57.
22. Tatemoto H, Muto N, Sunagawa I, Shinjo A, Nakada T. Protection of porcine oocytes against cell damage caused by oxidative stress during in vitro maturation: role of superoxide dismutase activity in porcine follicular fluid. Biol Reprod 2004, 71:1150-1157.
23. Whitaker BD, Knight JW. Exogenous γ-glutamyl cycle compounds supplemented to in vitro maturation medium influence in vitro fertilization, culture, and viability of porcine oocytes and embryos. Theriogenology 2004, 62:311-322.
24. Wu W, Goldstein G, Adams C, Matthews RH, Ercal N. Separation and quantification of N-acetyl-L-cysteine and N-acetyl-cysteine-amide by HPLC with fluorescence detection. Biomed Chromatogr 2006, 20:415-422.
25. Xu DX, Chen YH, Wang H, Zhao L, Wang JP, Wei W. Effect of N-acetylcysteine on lipopolysaccharide-induced intra-uterine fetal death and intra-uterine growth retardation in mice. Toxicol Sci 2005, 88:525-533.
26. Yim CY, Hibbs JB, McGregor JR, Galinsky RE, Samlowski WE. Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J Immunol 1994, 152:5796-5805.
27. Yoshida M, Ishigaki K, Pursel VG. Effect of maturation media on male pronucleus formation in pig oocytes matured in vitro. Mol Reprod Dev 1992, 31:68-71.
28. Yoshida M, Ishigaki K, Nagai T, Chikyu M, Pursel VG. Glutathione concentration during maturation and after fertilization in pig oocytes: relevance to the ability of oocytes to form male pronucleus. Biol Reprod 1993, 49:89-94.