Long range dynamic effects of point-mutations trap a response regulator in an active conformation

FEBS Letters

Volumn 584, Issue 19, 2010, Pages 4203-4207

  Bobay, Benjamin G ^a   Thompson, Richele J ^a   Hoch, James A ^b   Cavanagh, John ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Conformational transition; Intra protein communication; NMR; Response regulator; Spo0F

Indexed keywords

PROTEIN KINASE; PROTEIN SPOOF; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POINT MUTATION; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; THERMODYNAMICS;

EID: 77957111496     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.08.051     Document Type: Article

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