Adenosine 5'-triphosphate is the predominant source of peripheral adenosine in human B lymphoblasts

Journal of Physiology and Pharmacology

Volumn 61, Issue 4, 2010, Pages 491-499

  Sakowicz Burkiewicz, M ^a   Kocbuch, K ^a   Grden, M ^a   Szutowicz, A ^b   Pawelczyk, T ^a  

^a UNIVERSITY OF GDA SK   (Poland)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Adenosine; Adenosine 5' triphosphate release; Adenosine deaminase; B lymphocyte; Ecto 5' nucleotidase; Ecto ATPase

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE DIPHOSPHATE; BETA,GAMMA DIBROMOMETHYLENE 6 N,N DIETHYLADENOSINE TRIPHOSPHATE; NITROBENZYLTHIOINOSINE; PENTOSTATIN;

ARTICLE; B LYMPHOBLAST; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE METABOLISM;

ADENOSINE; ADENOSINE TRIPHOSPHATE; B-LYMPHOCYTE SUBSETS; CELL LINE; HUMANS; LYMPHOCYTE ACTIVATION;

EID: 77957098647     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. La Sala A, Ferrari D, Di Virgilio F, Idzko M, Norgauer J, Girolomoni G. Alerting and tuning the immune response by extracellular nucleotides. J Leukoc Biol 2003; 73: 339-343.
2. Zimmermann H. Extracellular metabolism of ATP and other nucleotides. Naunyn-Schmiedeberg's Arch Pharmacol 2000; 362: 299-309.
3. Bours MJ, Swennen EL, Di Virgilio F, Cronstein BN, Dagnelie PC. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 2006; 112: 358-404.
4. Fredholm BB, IJzerman AP, Jacobson KA, Klotz K-N, Linden J. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001; 53: 527-552.
5. Burnstock G, Knight G. Cellular distribution and functions of P2 receptor subtypes in different systems. Int Rev Cytol 2004; 240: 31-304.
6. Yegutkin GG. Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signaling cascade. Biochim Biophys Acta 2008; 1783: 673-694.
7. Podgorska M, Kocbuch K, Pawelczyk T. Recent advances in studies on biochemical and structural properties of equilibtrative and concentrative nucleoside transporters. Acta Biochim Pol 2005; 52: 749-758.
8. Yegutkin GG, Mikhailov A, Samburski SS, Jalkanen S. The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor. Mol Biol Cell 2006; 17: 3378-3385.
9. Podgorska M, Kocbuch K, Grden M, Szutowicz A, Pawelczyk T. Reduced ability to release adenosine by diabetic rat cardiac fibroblasts due to altered expression of nucleoside transporters. J Physiol 2006; 576: 179-189.
10. Sakowicz M, Szutowicz A, Pawelczyk T. Insulin and glucose induced changes in expression level of nucleoside transporters and adenosine transport in rat T lymphocytes. Biochem Pharmacol 2004; 68: 1304-1320.
11. Pawelczyk T, Sakowicz-Burkiewicz M, Kocbuch K, Szutowicz A. Differential effect of insulin and elevated glucose level on adenosine handling in rat T lymphocytes. J Cell Biochem 2005; 96: 1296-1310.
12. Lazarowski ER, Homolya L, Boucher RC, Harden TK. Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. J Biol Chem 1997; 272: 24348-24354.
13. Watt WC, Lazarowski ER, Boucher R. Cystic fibrosis transmembrane regulator-independent release of ATP. Its implications for the regulation of P2Y2 receptors in airway epithelia. J Biol Chem 1998; 273: 14053-14058.
14. Lazarowski ER, Boucher RC, Harden TK. Constitutive release of ATP and evidence for major contribution of ectonucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations. J Biol Chem 2000; 275: 31061-31068.
15. Ostrom RS, Gregorian C, Insel PA. Cellular release of and response to ATP as key determinants of the set-point of signal transduction pathways. J Biol Chem 2000; 275: 11735-11739.
16. Joseph SM, Buchakjian MR, Dubyak GR. Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes. J Biol Chem 2003; 278: 23331-23342.
17. Henderson JF, Brox L, Zombor G, Hunting D, Lomax CA. Specificity of adenosine deaminase inhibitors. Biochem Pharmacol 1977; 26: 1967-1972.
18. Barankiewicz J, Ronlov G, Jimenez R, Gruber HE. Selective adenosine release from human B but not T lymphoid cell line. J Biol Chem 1990; 265: 15738-15743.
19. Pastor-Anglada M, Casado FJ, Valdes R, Mata J, Garcia-Manteiga J, Molina M. Complex regulation of nucleoside transporter expression in epithelial and immune system cells. Mol Membr Biol 2001; 18: 81-85.
20. Molina-Arcas M, Bellosillo B, Casado FJ, Montserrat E, Gil J, Colomer D, Pastor-Anglada M. Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia. Blood 2003; 101: 2328-2334.
21. Sakowicz M, Szutowicz A, Pawelczyk T. Differential effect of insulin and elevated glucose level on adenosine transport in rat B lymphocytes. Int Immunol 2005; 17: 145-154.
22. Yegutkin GG, Henttinen T, Samburski SS, Spychala J, Jalkanen S. The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells. Biochem J 2002; 367(1): 121-128.
23. Kocbuch K, Sakowicz-Burkiewicz M, Grden M, Szutowicz A, Pawelczyk T. Effect of insulin and glucose on adenosine metabolizing enzymes in human B lymphocytes. Acta Biochim Pol 2009; 56(3): 439-446.
24. Naito Y, Lowenstein JM. 5'-Nucleotidase from rat heart membranes. Inhibition by adenine nucleotides and related compounds. Biochem J 1985; 226: 645-651.
25. Maliszewski CR, Delespesse GJ, Schoenborn MA, et al. The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization. J Immunol 1994; 153: 3574-3583.
26. Dwyer KM, Deaglio S, Gao W, Friedman D, Strom TB, Robson SC. CD39 and control of cellular immune responses. Purinergic Signal 2007; 3: 171-180.
27. Levesque SA, Lavoie EG, Lecka J, Bigonnesse F, Sevigny J. Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases. Br J Pharmacol 2007; 152: 141-150.
28. Bao L, Locovei S, Dahl G. Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett 2004; 572: 65-68.
29. Schenk U, Westendorf AM, Radaelli E, et al. Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels. Sci Signal 2008; 1(39): ra6.
30. McLennan AG. Dinucleoside polyphosphates-friend or foe? Pharmacol Ther 2000; 87: 73-89.
31. Jankowski M. Purinergic regulation of glomerular microvasculature and tubular function. J Physiol Pharmacol 2008; 59(Suppl. 9): 121-135.
32. Jankowski M, Angielski S, Szczepanska-Konkel M. Dissociation between the effects of P1,P4-diadenosine tetraphosphate (Ap4A) on renal haemodynamics and tubular function in aneasthetized rats. J Physiol Pharmacol 2008; 59(1): 129-137.
33. Bobbert B, Schluter H, Schlutheiss HP, Reusch HP. Diadenosine polyphosphates Ap3A and Ap4A, but not Ap5A or Ap6A, induce proliferation of vascular smooth muscle cells. Biochem Pharmacol 2008; 75: 1966-1973.
34. Szczepanska-Konkel M, Jankowski M, Stiepanow-Trzeciak A, Angielski S. Effects of diadenosine polyphosphates on glomerular volume. Br J Pharmacol 2005; 144: 1109-1117.
35. Sakowicz-Burkiewicz M, Kocbuch K, Grden M, Szutowicz A, Pawelczyk T. Protein kinase C mediated high glucose effect on adenosine receptors expression in rat B lymphocytes. J Physiol Pharmacol 2009; 60(3): 145-153.
36. Farias M III, Gorman MW, Savage MV, Feigl EO. Plasma ATP during exercise: possible role in regulation of coronary blood flow. Am J Physiol Heart Cir Physiol 2005; 288: H1586-H1590.
37. Gorman MW, Feigl EO, Buffington CW. Human plasma ATP concentration. Clin Chem 2007; 53: 318-325.
38. Goepfert C, Sundberg C, Sevigny J, et al. Disordered cellular migration and angiogenesis in cd39-null mice. Circulation 2001; 104: 3109-3115.
39. Koszalka P, Ozuyaman B, Huo Y, et al. Targeted disruption of CD73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response. Cir Res 2004; 95: 814-821.
40. Yegutkin GG, Henttinen T, Jalkanen S. Extracellular ATP formation on vascular endothelial cells is mediated by ectonucleotide kinase activities via phosphotransfer reactions. FASEB J 2001; 15: 251-260.
41. Fabre AC, Vantourout P, Champagne E, et al. Cell surface adenylate kinase activity regulates the F(1)- ATPase/P2Y(13)-mediated HDL endocytosis pathway on human hepatocytes. Cell Mol Life Sci 2006; 63: 2829-2837.
42. Burrel HE, Wlodarski B, Foster BJ, et al. Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface. J Biol Chem 2005; 280: 29667-29676.
43. Donaldson SH, Picher M, Boucher RC. Secreted and cellassociated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces. Am J Respir Cell Mol Biol 2002; 26: 209-215.
44. Zimmermann H. Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system. Prog Neurobiol 1996; 49: 589-618.
45. Sevigny J, Levesque FP, Grondin G, Beaudoin AR. Purification of the blood vessel ATP diphosphohydrolase, identification and localisation by immunological techniques. Biochim Biophys Acta 1997; 1334: 73-88.
46. Dombrowski KE, Ke Y, Brewer KA, Kapp JA. Ecto-ATPase: anactivation marker necessary for effector cell function. Immunol Rev 1998; 161: 111-118.