International workshop at the nobel forum, karolinska institutet on g protein-coupled receptors: Finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached

Journal of Receptors and Signal Transduction

Volumn 30, Issue 5, 2010, Pages 284-286

  Kenakin, Terry ^a   Agnati, Luigi F ^b   Caron, Marc ^c   Fredholm, Bertil ^d   Guidoli, Diego ^e   Kobilka, Brian ^f   Lefkowitz, Robert W ^c   Lohse, Martin ^g   Woods, Amina ^h   Fuxe, Kjell ^d  

^a GLAXOSMITHKLINE   (United States)

^b IRCCS   (Italy)

^c DUKE UNIVERSITY   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY OF PADOVA   (Italy)

^f STANFORD UNIVERSITY   (United States)

^g UNIVERSITY OF WÜRZBURG   (Germany)

^h NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; MONOMER; OLIGOMER;

ALLOSTERISM; CONFERENCE PAPER; CONSENSUS; LIGAND BINDING; OLIGOMERIZATION; PROTEIN PROTEIN INTERACTION; WORKSHOP;

EID: 77957097202     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2010.512438     Document Type: Conference Paper

References (7)

1. Azzi M, Charest PG, Anger S, Rousseau G, Kohout T, Bouvier M. β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proc Natl Acad Sci USA 2003, 100, 11406-11411.
2. Fuxe K, Agnati LF. Receptor-Receptor Interactions. A New Intramembrane Integrative Mechanism. London UK, MacMillan Press, 1987
3. Galandrin S, Bouvier M. Distinct signaling profiles of β1 and β2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Mol Pharmacol 2006, 70, 1575-1584
4. Hejnová L, Tucek S, el-Fakahany EE. Positive and negative allosteric interactions on muscarinic receptors. Eur J Pharmacol 1995, 291, 427-430
5. Mukhopadhyay S, Howlett AC. Chemically distinct ligands promote differential CB1 cannabinoid receptor-Gi protein interactions. Mol Pharmacol 2005, 67, 2016-2024
6. Violin JD, Lekowitz RJ. β-Arrestin-biased ligands at seven transmembrane receptors. Trends Pharmacol Sci 2007, 28, 416-422
7. Wei H, Ahn S, Shenoy SK, Karnik SS, Hunyady L, Luttrell LM, Lefkowitz RJ. Independent beta-arrestin 2 and G protein mediated pathways for angiotensin II activation of extracellular signal- regulated kinases 1 and 2. Proc Natl Acad Sci USA 2003, 100, 10782-10787.