Inhibitory effects of oral disulfiram on endotoxin-induced uveitis in rats

Current Eye Research

Volumn 35, Issue 10, 2010, Pages 892-899

  Kanai, Kazutaka ^a   Itoh, Naoyuki ^a   Yoshioka, Kazuki ^a   Yonezawa, Tomohiro ^a   Ikadai, Hiromi ^a   Hori, Yasutomo ^a   Ito, Yoshimasa ^b   Nagai, Noriaki ^b   Chikazawa, Seishirou ^a   Hoshi, Fumio ^a   Higuchi, Seiichi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b KINKI UNIVERSITY   (Japan)

Author keywords

Anti inflammatory effects; Diethyldithiocarbamate; Disulfiram; Endotoxin induced uveitis; Nuclear factor kappa B

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; DISULFIRAM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANTERIOR EYE CHAMBER; ANTIINFLAMMATORY ACTIVITY; AQUEOUS HUMOR; ARTICLE; CELL INFILTRATION; CILIARY BODY; CLINICAL EVALUATION; DOSE RESPONSE; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; EYE PROTECTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME; UVEITIS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; AQUEOUS HUMOR; CILIARY BODY; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DISULFIRAM; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; ENDOTOXINS; EYE PROTEINS; INFLAMMATION MEDIATORS; MALE; NF-KAPPA B; NITRIC OXIDE; OSMOLAR CONCENTRATION; RATS; RATS, INBRED LEW; TUMOR NECROSIS FACTOR-ALPHA; UVEITIS;

EID: 77957077049     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2010.495442     Document Type: Article

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