Correlation of active site metal content in human diamine oxidase with trihydroxyphenylalanine quinone cofactor biogenesis

Biochemistry

Volumn 49, Issue 38, 2010, Pages 8316-8324

  McGrath, Aaron P ^a   Caradoc Davies, Tom ^b   Collyer, Charles A ^a   Guss, J Mitchell ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AUSTRALIAN SYNCHROTRON   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; MOLECULAR OXYGEN; X RAY DIFFRACTION; ZINC;

ACTIVE SITE; AMINE OXIDASE; CATALYTIC METALS; COFACTORS; COPPER AND ZINC; DIAMINE OXIDASE; METAL CONTENT; METAL SITES; POTENT INHIBITOR; TOPAQUINONE; X-RAY DIFFRACTION DATA;

COPPER;

AMINE OXIDASE (COPPER CONTAINING); AMINOGUANIDINE; COPPER; QUINONE DERIVATIVE; TRIHYDROXYPHENYLALANINE QUINONE COFACTOR; UNCLASSIFIED DRUG; ZINC; 6-HYDROXYDOPA QUINONE; BENZOQUINONE; BENZOQUINONE DERIVATIVE; DOPA; METAL; RECOMBINANT PROTEIN;

ARTICLE; BIOGENESIS; COVALENT BOND; CRYSTAL STRUCTURE; DROSOPHILA; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME STRUCTURE; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOICHIOMETRY; X RAY DIFFRACTION; ANALOGS AND DERIVATIVES; BINDING SITE; CHEMISTRY; HUMAN; METABOLISM;

AMINE OXIDASE (COPPER-CONTAINING); BENZOQUINONES; BINDING SITES; COPPER; DIHYDROXYPHENYLALANINE; HUMANS; METALS; QUINONES; RECOMBINANT PROTEINS; X-RAY DIFFRACTION; ZINC;

EID: 77957041848     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1010915     Document Type: Article

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