Autophagy inhibition sensitizes multiple myeloma cells to 17-dimethylaminoethylamino-17-demethoxygeldanamycin-induced apoptosis

Leukemia Research

Volumn 34, Issue 11, 2010, Pages 1533-1538

  Palacios, Carmen ^a   Martín Pérez, Rosa ^a   López Pérez, Ana Isabel ^a   Pandiella, Atanasio ^b   López Rivas, Abelardo ^a  

^a CSIC   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

17DMAG; 3 MA; Apoptosis; Autophagy; Multiple myeloma

Indexed keywords

17 DEMETHOXY 17 (2 DIMETHYLAMINOETHYLAMINO)GELDANAMYCIN; 3 METHYLADENINE; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG; 17-(DIMETHYLAMINOETHYLAMINO)-17-DEMETHOXYGELDANAMYCIN; 3-METHYLADENINE; ADENINE; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; HEAT SHOCK PROTEIN 90; MACROCYCLIC LACTAM;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENTIATION; DRUG SENSITIZATION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIGHT CHAIN; MITOCHONDRIAL MEMBRANE POTENTIAL; MULTIPLE MYELOMA; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN SECRETION; UPREGULATION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PATHOLOGY;

ADENINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BENZOQUINONES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MITOCHONDRIA; MULTIPLE MYELOMA;

EID: 77957021127     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.07.002     Document Type: Article

References (8)

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