메뉴 건너뛰기




Volumn 147, Issue 2, 2010, Pages 202-210

The mechanism of protein release from triglyceride microspheres

Author keywords

Confocal microscopy; Lipid microspheres; Particle distribution; Protein release; Release mechanism

Indexed keywords

BOVINE SERUM ALBUMINS; CONFOCAL LASER SCANNING MICROSCOPY; CROSS SECTION; FREEZE-DRIED MATERIALS; HIGH UNIFORMITY; JET MILLING; LASER-LIGHT DIFFRACTION; LIGHT MICROSCOPY; PARTICLE DISTRIBUTIONS; PHOSPHATE BUFFERS; POLYDISPERSE PROTEINS; PRECIPITATED PROTEINS; PROTEIN PARTICLES; PROTEIN RELEASE; PROTEIN RELEASE KINETICS; RELEASE KINETICS; RELEASE MECHANISM; SHAPED PARTICLES; SPHERICAL PARTICLE; STRONG CORRELATION;

EID: 77957019705     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.110     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 26944499416 scopus 로고    scopus 로고
    • Biopharmaceuticals: recent approvals and likely directions
    • Walsh G. Biopharmaceuticals: recent approvals and likely directions. Trends Biotechnol. 2005, 23(11):553-558.
    • (2005) Trends Biotechnol. , vol.23 , Issue.11 , pp. 553-558
    • Walsh, G.1
  • 3
    • 34248582291 scopus 로고    scopus 로고
    • Towards controlled release of BDNF - manufacturing strategies for protein-loaded lipid implants and biocompatibility evaluation in the brain
    • Koennings S., Sapin A., Blunk T., Menei P., Goepferich A. Towards controlled release of BDNF - manufacturing strategies for protein-loaded lipid implants and biocompatibility evaluation in the brain. J. Control. Release 2007, 119(2):163-172.
    • (2007) J. Control. Release , vol.119 , Issue.2 , pp. 163-172
    • Koennings, S.1    Sapin, A.2    Blunk, T.3    Menei, P.4    Goepferich, A.5
  • 4
    • 0037241589 scopus 로고    scopus 로고
    • Monolithic glyceryl trimyristatematrices for parenteral drug release applications
    • Vogelhuber W., Magni E., Gazzaniga A., Goepferich A. Monolithic glyceryl trimyristatematrices for parenteral drug release applications. Eur. J. Pharm. Biopharm. 2003, 55(1):133-138.
    • (2003) Eur. J. Pharm. Biopharm. , vol.55 , Issue.1 , pp. 133-138
    • Vogelhuber, W.1    Magni, E.2    Gazzaniga, A.3    Goepferich, A.4
  • 5
    • 0037130249 scopus 로고    scopus 로고
    • Precise control of PLG microsphere size provides enhanced control of drug release rate
    • Berkland C., King M., Cox A., Kim K., Pack D.W. Precise control of PLG microsphere size provides enhanced control of drug release rate. J. Control. Release 2002, 82:137-147.
    • (2002) J. Control. Release , vol.82 , pp. 137-147
    • Berkland, C.1    King, M.2    Cox, A.3    Kim, K.4    Pack, D.W.5
  • 6
    • 33751364274 scopus 로고    scopus 로고
    • Biodegradable micro- and nanoparticles as long-term delivery vehicles for gentamicin
    • Lecaroz C., Gamazo C., Renedo M.J., Blanco-Prieto M.J. Biodegradable micro- and nanoparticles as long-term delivery vehicles for gentamicin. J. Microencapsul. 2006, 23:782-792.
    • (2006) J. Microencapsul. , vol.23 , pp. 782-792
    • Lecaroz, C.1    Gamazo, C.2    Renedo, M.J.3    Blanco-Prieto, M.J.4
  • 7
    • 33750471911 scopus 로고    scopus 로고
    • Vitamin A palmitate and aciclovir biodegradable microspheres for intraocular sustained release
    • Martínez-Sancho C., Herrero-Vanrell R., Negro S. Vitamin A palmitate and aciclovir biodegradable microspheres for intraocular sustained release. Int. J. Pharm. 2006, 326:100-106.
    • (2006) Int. J. Pharm. , vol.326 , pp. 100-106
    • Martínez-Sancho, C.1    Herrero-Vanrell, R.2    Negro, S.3
  • 8
    • 0141955243 scopus 로고    scopus 로고
    • Preparation and characterization of poly(lactic acid)-poly(ethyleneglycol)-poly(lactic acid) (PLA-PEG-PLA) microspheres for controlled release of paclitaxel
    • Ruana G., Feng S. Preparation and characterization of poly(lactic acid)-poly(ethyleneglycol)-poly(lactic acid) (PLA-PEG-PLA) microspheres for controlled release of paclitaxel. Biomaterials 2003, 24:5037-5044.
    • (2003) Biomaterials , vol.24 , pp. 5037-5044
    • Ruana, G.1    Feng, S.2
  • 9
    • 0037151323 scopus 로고    scopus 로고
    • Characterization of the initial burst release of a model peptide from poly(d,l-lactide-co-glycolide) microspheres
    • Wang J., Wang B.A., Schwendeman S.P. Characterization of the initial burst release of a model peptide from poly(d,l-lactide-co-glycolide) microspheres. J. Control. Release 2002, 82:289-307.
    • (2002) J. Control. Release , vol.82 , pp. 289-307
    • Wang, J.1    Wang, B.A.2    Schwendeman, S.P.3
  • 10
    • 33646174102 scopus 로고    scopus 로고
    • Lipidic implants for controlled release of bioactive insulin: effects on cartilage engineered in vitro
    • Appel B., Maschke A., Weiser B., Sarhan H., Englert C., Angele P., Blunk T., Goepferich A. Lipidic implants for controlled release of bioactive insulin: effects on cartilage engineered in vitro. Int. J. Pharm. 2006, 314(2):170-178.
    • (2006) Int. J. Pharm. , vol.314 , Issue.2 , pp. 170-178
    • Appel, B.1    Maschke, A.2    Weiser, B.3    Sarhan, H.4    Englert, C.5    Angele, P.6    Blunk, T.7    Goepferich, A.8
  • 11
    • 33845945504 scopus 로고    scopus 로고
    • Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof
    • Maschke A., Becker C., Eyrich D., Kiermaier J., Blunk T., Gopferich A. Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof. Eur. J. Pharm. Biopharm. 2007, 65(2):175-187.
    • (2007) Eur. J. Pharm. Biopharm. , vol.65 , Issue.2 , pp. 175-187
    • Maschke, A.1    Becker, C.2    Eyrich, D.3    Kiermaier, J.4    Blunk, T.5    Gopferich, A.6
  • 12
    • 0035850227 scopus 로고    scopus 로고
    • Lipid microparticles as a parenteral controlled release device for peptides
    • Reithmeier H., Herrmann J., Gopferich A. Lipid microparticles as a parenteral controlled release device for peptides. J. Control. Release 2001, 73(2-3):339-350.
    • (2001) J. Control. Release , vol.73 , Issue.2-3 , pp. 339-350
    • Reithmeier, H.1    Herrmann, J.2    Gopferich, A.3
  • 13
    • 0035821356 scopus 로고    scopus 로고
    • Development and characterization of lipid microparticles as a drug carrier for somatostatin
    • Reithmeier H., Herrmann J., Gopferich A. Development and characterization of lipid microparticles as a drug carrier for somatostatin. Int. J. Pharm. 2001, 218:133-143.
    • (2001) Int. J. Pharm. , vol.218 , pp. 133-143
    • Reithmeier, H.1    Herrmann, J.2    Gopferich, A.3
  • 14
    • 2442600113 scopus 로고    scopus 로고
    • Continuous release of rh-interferon α-2a from triglyceride matrices
    • Mohl S., Winter G. Continuous release of rh-interferon α-2a from triglyceride matrices. J. Control. Release 2004, 97(1):67-78.
    • (2004) J. Control. Release , vol.97 , Issue.1 , pp. 67-78
    • Mohl, S.1    Winter, G.2
  • 16
    • 33646176846 scopus 로고    scopus 로고
    • In vitro investigation of lipid implants as a controlled release system for interleukin-18
    • Koennings S., Garcion E., Faisant N., Menei J.P., Benoit J.P., Goepferich A. In vitro investigation of lipid implants as a controlled release system for interleukin-18. Int. J. Pharm. 2006, 314(2):145-152.
    • (2006) Int. J. Pharm. , vol.314 , Issue.2 , pp. 145-152
    • Koennings, S.1    Garcion, E.2    Faisant, N.3    Menei, J.P.4    Benoit, J.P.5    Goepferich, A.6
  • 17
    • 0032713463 scopus 로고    scopus 로고
    • Preparation and characterization of lipid microparticles containing thymocartin, an immunomodulating peptide
    • Reithmeier H., Goepferich A., Herrmann J. Preparation and characterization of lipid microparticles containing thymocartin, an immunomodulating peptide. Proc. Int. Symp. Control. Release Bioact. Mater. 1999, 681-682.
    • (1999) Proc. Int. Symp. Control. Release Bioact. Mater. , pp. 681-682
    • Reithmeier, H.1    Goepferich, A.2    Herrmann, J.3
  • 18
    • 34249909240 scopus 로고    scopus 로고
    • Confocal microscopy for the elucidation of mass transport mechanisms involved in protein release from lipid-based matrices
    • Koennings S., Tessmar J., Blunk T., Goepferich A. Confocal microscopy for the elucidation of mass transport mechanisms involved in protein release from lipid-based matrices. Pharm. Res. 2007, 24(7):1325-1335.
    • (2007) Pharm. Res. , vol.24 , Issue.7 , pp. 1325-1335
    • Koennings, S.1    Tessmar, J.2    Blunk, T.3    Goepferich, A.4
  • 19
    • 34248589097 scopus 로고    scopus 로고
    • Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices
    • Koennings S., Berié A., Tessmar J., Blunk T., Goepferich A. Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices. J. Control. Release 2007, 119:173-181.
    • (2007) J. Control. Release , vol.119 , pp. 173-181
    • Koennings, S.1    Berié, A.2    Tessmar, J.3    Blunk, T.4    Goepferich, A.5
  • 20
    • 2442600113 scopus 로고    scopus 로고
    • Continuous release of rh-interferon alpha-2a from triglyceride matrices
    • Mohl S., Winter G. Continuous release of rh-interferon alpha-2a from triglyceride matrices. J. Control. Release 2004, 97:67-78.
    • (2004) J. Control. Release , vol.97 , pp. 67-78
    • Mohl, S.1    Winter, G.2
  • 22
    • 0028960948 scopus 로고
    • Effect of varying drug loading on particle size distribution and drug release kinetics of verapamil hydrochloride microspheres prepared with cellulose esters
    • Bhardwaj S.B., Shukla A.J., Collins C.C. Effect of varying drug loading on particle size distribution and drug release kinetics of verapamil hydrochloride microspheres prepared with cellulose esters. J. Microencaspsul. 1995, 12(1):71-81.
    • (1995) J. Microencaspsul. , vol.12 , Issue.1 , pp. 71-81
    • Bhardwaj, S.B.1    Shukla, A.J.2    Collins, C.C.3
  • 24
    • 0021241808 scopus 로고
    • Controlled release of polypeptides and other macromolecules
    • Siegel R., Langer R. Controlled release of polypeptides and other macromolecules. Pharm. Res. 1984, 1:2-10.
    • (1984) Pharm. Res. , vol.1 , pp. 2-10
    • Siegel, R.1    Langer, R.2
  • 26
    • 34547899919 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as a drug delivery system for peptides and proteins
    • Almeida A.J., Souto E. Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv. Drug Deliv. Rev. 2007, 59:478-490.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 478-490
    • Almeida, A.J.1    Souto, E.2
  • 27
    • 0034493158 scopus 로고    scopus 로고
    • Formation and isolation of spherical fine protein microparticles through lyophilization of protein-poly(ethyleneglycol) aqueous mixture
    • Morita T., Horikiri Y., Yamahara H., Suzuki T., Yoshino H. Formation and isolation of spherical fine protein microparticles through lyophilization of protein-poly(ethyleneglycol) aqueous mixture. Pharm. Res. 2000, 17(11):1367-1373.
    • (2000) Pharm. Res. , vol.17 , Issue.11 , pp. 1367-1373
    • Morita, T.1    Horikiri, Y.2    Yamahara, H.3    Suzuki, T.4    Yoshino, H.5
  • 29
    • 0033039914 scopus 로고    scopus 로고
    • Stabilization of proteins against methylene chloride/water interface induced denaturation and aggregation
    • Sah H. Stabilization of proteins against methylene chloride/water interface induced denaturation and aggregation. J. Control. Release 1999, 58:143-151.
    • (1999) J. Control. Release , vol.58 , pp. 143-151
    • Sah, H.1
  • 30
    • 11144331447 scopus 로고    scopus 로고
    • Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique
    • Trotta M., Cavalli R., Carlotti M.E., Battaglia L., Debernardi F. Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique. Int. J. Pharm. 2005, 288:281-288.
    • (2005) Int. J. Pharm. , vol.288 , pp. 281-288
    • Trotta, M.1    Cavalli, R.2    Carlotti, M.E.3    Battaglia, L.4    Debernardi, F.5
  • 31
    • 74049128678 scopus 로고    scopus 로고
    • Solid lipid microparticles produced by spray congealing: influence of the atomizer on microparticle characteristics and mathematical modeling of the drug release
    • Passerini N., Qi S., Albertini B., Grassi M., Rodriguez L., Craig D.Q.M. Solid lipid microparticles produced by spray congealing: influence of the atomizer on microparticle characteristics and mathematical modeling of the drug release. J. Pharm. Sci. 2010, 99:916-931.
    • (2010) J. Pharm. Sci. , vol.99 , pp. 916-931
    • Passerini, N.1    Qi, S.2    Albertini, B.3    Grassi, M.4    Rodriguez, L.5    Craig, D.Q.M.6
  • 33
    • 53549102484 scopus 로고    scopus 로고
    • An investigation into the mechanisms of drug release from taste-masking fatty acid microspheres
    • Qi S., Deutsch D., Craig D.Q.M. An investigation into the mechanisms of drug release from taste-masking fatty acid microspheres. J. Pharm. Sci. 2008, 97:3842-3854.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 3842-3854
    • Qi, S.1    Deutsch, D.2    Craig, D.Q.M.3
  • 34
    • 0346104839 scopus 로고    scopus 로고
    • Microsphere size, precipitation kinetics and drug distribution control drug release from biodegradable polyanhydride microspheres
    • Berklanda C., Kipperb M.J., Narasimhanb B., Kim K., Pack D.W. Microsphere size, precipitation kinetics and drug distribution control drug release from biodegradable polyanhydride microspheres. J. Control. Release 2004, 94:129-141.
    • (2004) J. Control. Release , vol.94 , pp. 129-141
    • Berklanda, C.1    Kipperb, M.J.2    Narasimhanb, B.3    Kim, K.4    Pack, D.W.5
  • 35
    • 0025730552 scopus 로고
    • The influence of surfactants on drug release from a hydrophobic matrix
    • Efentakis M., Al Hmoud H., Buckton G., Rajan Z. The influence of surfactants on drug release from a hydrophobic matrix. Int. J. Pharm. 1991, 70(1-2):153-158.
    • (1991) Int. J. Pharm. , vol.70 , Issue.1-2 , pp. 153-158
    • Efentakis, M.1    Al Hmoud, H.2    Buckton, G.3    Rajan, Z.4
  • 36
    • 10644231005 scopus 로고    scopus 로고
    • Role of blooming in determining the storage stability of lipid-based dosage forms
    • Khan N., Craig D.Q.M. Role of blooming in determining the storage stability of lipid-based dosage forms. J. Pharm. Sci. 2004, 93:2962-2971.
    • (2004) J. Pharm. Sci. , vol.93 , pp. 2962-2971
    • Khan, N.1    Craig, D.Q.M.2
  • 37
    • 0026074591 scopus 로고
    • Optimization of spray-dried and -congealed lipid micropellets and characterization of their surface morphology by scanning electron microscopy
    • Eldem T., Speiser P., Hincal A. Optimization of spray-dried and -congealed lipid micropellets and characterization of their surface morphology by scanning electron microscopy. Pharm. Res. 1991, 8:47-54.
    • (1991) Pharm. Res. , vol.8 , pp. 47-54
    • Eldem, T.1    Speiser, P.2    Hincal, A.3
  • 38
    • 20444447021 scopus 로고    scopus 로고
    • Thermal analysis of the crystallization and melting behaviour of lipid matrices and lipid nanoparticles containing high amounts of lecithin
    • Schubert M.A., Schicke B.C., Müller-Goymann C.C. Thermal analysis of the crystallization and melting behaviour of lipid matrices and lipid nanoparticles containing high amounts of lecithin. Int. J. Pharm. 2005, 298:242-254.
    • (2005) Int. J. Pharm. , vol.298 , pp. 242-254
    • Schubert, M.A.1    Schicke, B.C.2    Müller-Goymann, C.C.3
  • 39
    • 0025732814 scopus 로고
    • Polymorphic behavior of sprayed lipid micropellets and its evaluation by differential scanning calorimetry and scanning electron microscopy
    • Eldem T., Speiser P., Altorfer H. Polymorphic behavior of sprayed lipid micropellets and its evaluation by differential scanning calorimetry and scanning electron microscopy. Pharm. Res. 1991, 8:178-184.
    • (1991) Pharm. Res. , vol.8 , pp. 178-184
    • Eldem, T.1    Speiser, P.2    Altorfer, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.