A mechanistic modelling approach to polymer dissolution using magnetic resonance microimaging

Journal of Controlled Release

Volumn 147, Issue 2, 2010, Pages 232-241

  Kaunisto, Erik ^a   Abrahmsen Alami, Susanna ^b   Borgquist, Per ^c   Larsson, Anette ^d   Nilsson, Bernt ^a   Axelsson, Anders ^a  

^a LUND UNIVERSITY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c Gambro AB   (Sweden)

^d CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

ALE; Dissolution; Mathematical modelling; MRI; Polyethylene oxide

Indexed keywords

ALE; COMPUTATIONALLY EFFICIENT; CRITICAL PARAMETER; DIFFUSION MODEL; DISSOLUTION PROCESS; GEL LAYERS; MAGNETIC RESONANCE MICROIMAGING; MATHEMATICAL MODELLING; MODELLING APPROACHES; MRI; POLYMER DISSOLUTION; STIRRING RATES; TEXTURE ANALYSIS METHOD; WATER CONCENTRATIONS;

DISSOLUTION; GELS; MAGNETIC RESONANCE; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYETHYLENES; SENSITIVITY ANALYSIS; THERMOPLASTICS;

MATHEMATICAL MODELS;

MACROGOL; POLYMER; WATER;

ANALYTIC METHOD; ARTICLE; CALIBRATION; DIFFUSION; DISSOLUTION; EXPERIMENTAL STUDY; GEL; MATHEMATICAL MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TABLET; WATER TRANSPORT;

DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; MAGNETIC RESONANCE IMAGING; MODELS, CHEMICAL; PHASE TRANSITION; POLYMERS; SOLUBILITY; SOLVENTS; TABLETS;

EID: 77957016262     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.102     Document Type: Article

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