Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 34, 2010, Pages 15199-15204

  Rouet, Vincent ^a,b   Bogorad, Roman L ^a,b,f   Kayser, Christine ^a,b   Kessal, Karima ^a,b   Genestie, Catherine ^c   Bardier, Armelle ^c   Grattan, David R ^d   Kelder, Bruce ^e   Kopchick, John J ^e   Kelly, Paul A ^a,b   Goffin, Vincent ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d UNIVERSITY OF OTAGO   (New Zealand)

^e OHIO UNIVERSITY   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Antagonist; Autocrine; Del1 9 G129R; p63; Stat5

Indexed keywords

DELTA 1-9 G129R HPRL PROTEIN; HORMONE RECEPTOR BLOCKING AGENT; PROLACTIN; PROLACTIN RECEPTOR; PROTEIN P63; RECOMBINANT PROLACTIN; STAT5 PROTEIN; STEM CELL ANTIGEN 1; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT; PRIMER DNA; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL CELL; CANCER INVASION; CARCINOGENESIS; CELL PROLIFERATION; CELL SUBPOPULATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG POTENCY; EPITHELIUM BASAL CELL; FEMALE; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PRECANCER; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER; PROSTATE CARCINOMA; PROSTATE TUMOR; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL EXPANSION; TRANSGENICS; TUMOR CELL; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CANCER STEM CELL; CBA MOUSE; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; NEOPLASM; NUCLEOTIDE SEQUENCE; PATHOLOGY; RAT; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

MUS MUSCULUS;

ANIMALS; BASE SEQUENCE; CELL PROLIFERATION; DNA PRIMERS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; NEOPLASMS, HORMONE-DEPENDENT; NEOPLASTIC STEM CELLS; PEPTIDE FRAGMENTS; PROLACTIN; PROSTATE; PROSTATIC NEOPLASMS; RATS; RECEPTORS, PROLACTIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TISSUE DISTRIBUTION;

EID: 77957003255     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911651107     Document Type: Article

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