AIDS-protective HLA-B*27/B*57 and chimpanzee MHC class I molecules target analogous conserved areas of HIV-1/SIVcpz

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 34, 2010, Pages 15175-15180

  De Groot, Natasja G ^a   Heijmans, Corrine M C ^a   Zoet, Yvonne M ^b   De Ru, Arnoud H ^b   Verreck, Frank A ^a   Van Veelen, Peter A ^b   Drijfhout, Jan W ^b   Doxiadis, Gaby G M ^a   Remarque, Edmond J ^a   Doxiadis, Ilias I N ^b   Van Rood, Jon J ^b   Koning, Frits ^b   Bontropa, Ronald E ^a,c  

^a BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

HIV SIV; Peptide binding; Selection; Selective sweep

Indexed keywords

GAG PROTEIN; HLA B27 ANTIGEN; HLA B57 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; HLA ANTIGEN CLASS 1; HLA B ANTIGEN; HLA-B57;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELLULAR IMMUNITY; CHIMPANZEE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS LOAD; VIRUS REPLICATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CYTOTOXIC T LYMPHOCYTE; GENE; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PAN TROGLODYTES; PROTEIN BINDING; SPECIES DIFFERENCE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; PAN; SIMIAN IMMUNODEFICIENCY VIRUS;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CONSERVED SEQUENCE; GENE PRODUCTS, GAG; GENES, MHC CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV LONG-TERM SURVIVORS; HIV-1; HLA-B ANTIGENS; HLA-B27 ANTIGEN; HUMANS; MOLECULAR SEQUENCE DATA; PAN TROGLODYTES; PROTEIN BINDING; SIMIAN IMMUNODEFICIENCY VIRUS; SPECIES SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC;

EID: 77956994615     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009136107     Document Type: Article

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