메뉴 건너뛰기




Volumn 70, Issue 18, 2010, Pages 7017-7026

MRE11 expression is predictive of cause-specific survival following radical radiotherapy for muscle-invasive bladder cancer

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; HISTONE H2AX; KI67; MRE11 PROTEIN; NIBRIN; PROTEIN P53; RAD50 PROTEIN; UNCLASSIFIED DRUG; ATM PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; H2AFX PROTEIN, HUMAN; HISTONE; MRE11A PROTEIN, HUMAN; NBN PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN SERINE THREONINE KINASE; RAD50 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

EID: 77956945628     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1202     Document Type: Article
Times cited : (184)

References (37)
  • 1
    • 84925572240 scopus 로고    scopus 로고
    • London: Cancer Research UK; updated Aug 27;cited 2010 Mar 24. Available from
    • Cancer incidence - UK statistics [Internet]. London: Cancer Research UK; [updated 2009 Aug 27;cited 2010 Mar 24]. Available from: http://info. cancerresearchuk.org/cancerstats/incidence/.
    • (2009) Cancer Incidence - UK Statistics [Internet]
  • 2
    • 38149110502 scopus 로고    scopus 로고
    • Similar treatment outcomes for radical cystectomy and radical radiotherapy in invasive bladder cancer treated at a United Kingdom specialist treatment center
    • Kotwal S, Choudhury A, Johnston C, Paul AB, Whelan P, Kiltie AE. Similar treatment outcomes for radical cystectomy and radical radiotherapy in invasive bladder cancer treated at a United Kingdom specialist treatment center. Int J Radiat Oncol Biol Phys 2008;70:456-63.
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 456-463
    • Kotwal, S.1    Choudhury, A.2    Johnston, C.3    Paul, A.B.4    Whelan, P.5    Kiltie, A.E.6
  • 3
    • 77956941676 scopus 로고    scopus 로고
    • SPARE: A qualitative study investigating randomization barriers in a Selective Bladder Preservation trial (SBP)
    • Moynihan C, Hall E, Lewis R, Birtle A, Mead GM, Huddart R. SPARE: a qualitative study investigating randomization barriers in a Selective Bladder Preservation trial (SBP). J Clin Oncol 2009;27:15s.
    • (2009) J Clin Oncol , vol.27
    • Moynihan, C.1    Hall, E.2    Lewis, R.3    Birtle, A.4    Mead, G.M.5    Huddart, R.6
  • 4
    • 0037612279 scopus 로고    scopus 로고
    • Improving and predicting radiosensitivity in muscle invasive bladder cancer
    • Colquhoun AJ, Jones GD, Moneef MA, et al. Improving and predicting radiosensitivity in muscle invasive bladder cancer. J Urol 2003; 169:1983-92.
    • (2003) J Urol , vol.169 , pp. 1983-1992
    • Colquhoun, A.J.1    Jones, G.D.2    Moneef, M.A.3
  • 5
    • 52249091114 scopus 로고    scopus 로고
    • Dancing on damaged chromatin: Functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage
    • Tokyo
    • Iijima K, Ohara M, Seki R, Tauchi H. Dancing on damaged chromatin: functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage. J Radiat Res (Tokyo) 2008;49:451-64.
    • (2008) J Radiat Res , vol.49 , pp. 451-464
    • Iijima, K.1    Ohara, M.2    Seki, R.3    Tauchi, H.4
  • 6
    • 36949013395 scopus 로고    scopus 로고
    • ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
    • Lavin MF. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene 2007;26:7749-58.
    • (2007) Oncogene , vol.26 , pp. 7749-7758
    • Lavin, M.F.1
  • 7
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009;461:1071-8.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 8
    • 24744469043 scopus 로고    scopus 로고
    • ATM expression in rectal cancers with or without preoperative radiotherapy
    • Arlehag L, Adell G, Knutsen A, Thorstenson S, Sun XF. ATM expression in rectal cancers with or without preoperative radiotherapy. Oncol Rep 2005;14:313-7.
    • (2005) Oncol Rep , vol.14 , pp. 313-317
    • Arlehag, L.1    Adell, G.2    Knutsen, A.3    Thorstenson, S.4    Sun, X.F.5
  • 10
    • 0029919634 scopus 로고    scopus 로고
    • Somatic point mutations in the p53 gene of human tumors and cell lines: Updated compilation
    • Hollstein M, Shomer B, Greenblatt M, et al. Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Res 1996;24:141-6.
    • (1996) Nucleic Acids Res , vol.24 , pp. 141-146
    • Hollstein, M.1    Shomer, B.2    Greenblatt, M.3
  • 11
    • 29744450338 scopus 로고    scopus 로고
    • Assessing p53 in clinical contexts: Unlearned lessons and new perspectives
    • Hall PA, McCluggage WG. Assessing p53 in clinical contexts: unlearned lessons and new perspectives. J Pathol 2006;208:1-6.
    • (2006) J Pathol , vol.208 , pp. 1-6
    • Hall, P.A.1    McCluggage, W.G.2
  • 12
    • 11144357075 scopus 로고    scopus 로고
    • p53 and p21 Expression levels predict organ preservation and survival in invasive bladder carcinoma treated with a combined-modality approach
    • Garcia del Muro X, Condom E, Vigues F, et al. p53 and p21 Expression levels predict organ preservation and survival in invasive bladder carcinoma treated with a combined-modality approach. Cancer 2004;100:1859-67.
    • (2004) Cancer , vol.100 , pp. 1859-1867
    • Garcia Del Muro, X.1    Condom, E.2    Vigues, F.3
  • 13
    • 0029086929 scopus 로고
    • p53 and Rb immunostaining in locally advanced bladder cancer: Relation to prognostic variables and predictive value for the local response to radical radiotherapy
    • Jahnson S, Risberg B, Karlsson MG, Westman G, Bergstrom R, Pedersen J. p53 and Rb immunostaining in locally advanced bladder cancer: relation to prognostic variables and predictive value for the local response to radical radiotherapy. Eur Urol 1995;28:135-42.
    • (1995) Eur Urol , vol.28 , pp. 135-142
    • Jahnson, S.1    Risberg, B.2    Karlsson, M.G.3    Westman, G.4    Bergstrom, R.5    Pedersen, J.6
  • 14
    • 0035312197 scopus 로고    scopus 로고
    • Apoptosis, proliferation and p53, cyclin D1, and retinoblastoma gene expression in relation to radiation response in transitional cell carcinoma of the bladder
    • Moonen L, Ong F, Gallee M, et al. Apoptosis, proliferation and p53, cyclin D1, and retinoblastoma gene expression in relation to radiation response in transitional cell carcinoma of the bladder. Int J Radiat Oncol Biol Phys 2001;49:1305-10.
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 1305-1310
    • Moonen, L.1    Ong, F.2    Gallee, M.3
  • 15
    • 0031865344 scopus 로고    scopus 로고
    • Prognostic factors in muscle-invasive bladder cancer treated with radiotherapy: An immunohistochemical study
    • Osen I, Fossa SD, Majak B, Rotterud R, Berner A. Prognostic factors in muscle-invasive bladder cancer treated with radiotherapy: an immunohistochemical study. Br J Urol 1998;81:862-9.
    • (1998) Br J Urol , vol.81 , pp. 862-869
    • Osen, I.1    Fossa, S.D.2    Majak, B.3    Rotterud, R.4    Berner, A.5
  • 16
    • 0035529043 scopus 로고    scopus 로고
    • Combined p21WAF1/ CIP1 and p53 overexpression predict improved survival in muscleinvasive bladder cancer treated by radical radiotherapy
    • Qureshi KN, Griffiths TR, Robinson MC, et al. Combined p21WAF1/ CIP1 and p53 overexpression predict improved survival in muscleinvasive bladder cancer treated by radical radiotherapy. Int J Radiat Oncol Biol Phys 2001;51:1234-40.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 1234-1240
    • Qureshi, K.N.1    Griffiths, T.R.2    Robinson, M.C.3
  • 17
    • 0034834191 scopus 로고    scopus 로고
    • p53, p21 and mdm2 expression vs the response to radiotherapy in transitional cell carcinoma of the bladder
    • Rotterud R, Berner A, Holm R, Skovlund E, Fossa SD. p53, p21 and mdm2 expression vs the response to radiotherapy in transitional cell carcinoma of the bladder. BJU Int 2001;88:202-8.
    • (2001) BJU Int , vol.88 , pp. 202-208
    • Rotterud, R.1    Berner, A.2    Holm, R.3    Skovlund, E.4    Fossa, S.D.5
  • 18
    • 0029922215 scopus 로고    scopus 로고
    • Prognostic value of p53 in muscle-invasive bladder cancer treated with preoperative radiotherapy
    • Wu CS, Pollack A, Czerniak B, et al. Prognostic value of p53 in muscle-invasive bladder cancer treated with preoperative radiotherapy. Urology 1996;47:305-10.
    • (1996) Urology , vol.47 , pp. 305-310
    • Wu, C.S.1    Pollack, A.2    Czerniak, B.3
  • 19
    • 24344451212 scopus 로고    scopus 로고
    • APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer
    • Sak SC, Harnden P, Johnston CF, Paul AB, Kiltie AE. APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer. Clin Cancer Res 2005;11:6205-11.
    • (2005) Clin Cancer Res , vol.11 , pp. 6205-6211
    • Sak, S.C.1    Harnden, P.2    Johnston, C.F.3    Paul, A.B.4    Kiltie, A.E.5
  • 20
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • Petitjean A, Mathe E, Kato S, et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007;28:622-9.
    • (2007) Hum Mutat , vol.28 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3
  • 21
    • 0036528610 scopus 로고    scopus 로고
    • Radical radiotherapy and salvage cystectomy as the primary management of transitional cell carcinoma of the bladder. Results following the introduction of a CT planning technique
    • Borgaonkar S, Jain A, Bollina P, et al. Radical radiotherapy and salvage cystectomy as the primary management of transitional cell carcinoma of the bladder. Results following the introduction of a CT planning technique. Clin Oncol (R Coll Radiol) 2002;14:141-7.
    • (2002) Clin Oncol (R Coll Radiol) , vol.14 , pp. 141-147
    • Borgaonkar, S.1    Jain, A.2    Bollina, P.3
  • 22
    • 34447096867 scopus 로고    scopus 로고
    • Long-term outcome of radiation-based conservation therapy for invasive bladder cancer
    • Chung PW, Bristow RG, Milosevic MF, et al. Long-term outcome of radiation-based conservation therapy for invasive bladder cancer. Urol Oncol 2007;25:303-9.
    • (2007) Urol Oncol , vol.25 , pp. 303-309
    • Chung, P.W.1    Bristow, R.G.2    Milosevic, M.F.3
  • 24
    • 0343775631 scopus 로고    scopus 로고
    • Apoptosis, p53, bcl-2, and Ki-67 in invasive bladder carcinoma: Possible predictors for response to radiochemotherapy and successful bladder preservation
    • Rodel C, Grabenbauer GG, Rodel F, et al. Apoptosis, p53, bcl-2, and Ki-67 in invasive bladder carcinoma: possible predictors for response to radiochemotherapy and successful bladder preservation. Int J Radiat Oncol Biol Phys 2000;46:1213-21.
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 1213-1221
    • Rodel, C.1    Grabenbauer, G.G.2    Rodel, F.3
  • 26
    • 33846568336 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff AC, Hammond ME, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med 2007;131:18-43.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 18-43
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 27
    • 56049096751 scopus 로고    scopus 로고
    • Technical pitfalls potentially affecting diagnoses in immunohistochemistry
    • Bussolati G, Leonardo E. Technical pitfalls potentially affecting diagnoses in immunohistochemistry. J Clin Pathol 2008;61:1184-92.
    • (2008) J Clin Pathol , vol.61 , pp. 1184-1192
    • Bussolati, G.1    Leonardo, E.2
  • 28
    • 42549116694 scopus 로고    scopus 로고
    • Current issues in ER and HER2 testing by IHC in breast cancer
    • Gown AM. Current issues in ER and HER2 testing by IHC in breast cancer. Mod Pathol 2008;21 Suppl 2:S8-15.
    • (2008) Mod Pathol , vol.21 , Issue.SUPPL. 2
    • Gown, A.M.1
  • 29
    • 1842614263 scopus 로고    scopus 로고
    • p53 and RB: Simple interesting correlates or tumor markers of critical predictive nature?
    • Cordon-Cardo C. p53 and RB: simple interesting correlates or tumor markers of critical predictive nature? J Clin Oncol 2004;22:975-7.
    • (2004) J Clin Oncol , vol.22 , pp. 975-977
    • Cordon-Cardo, C.1
  • 30
    • 18344395671 scopus 로고    scopus 로고
    • Human MRE11 is inactivated in mismatch repair-deficient cancers
    • Giannini G, Ristori E, Cerignoli F, et al. Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep 2002;3:248-54.
    • (2002) EMBO Rep , vol.3 , pp. 248-254
    • Giannini, G.1    Ristori, E.2    Cerignoli, F.3
  • 31
    • 21344452093 scopus 로고    scopus 로고
    • NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells
    • Zhang Y, Lim CU, Williams ES, et al. NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells. Cancer Res 2005;65:5544-53.
    • (2005) Cancer Res , vol.65 , pp. 5544-5553
    • Zhang, Y.1    Lim, C.U.2    Williams, E.S.3
  • 32
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • Oren M. Decision making by p53: life, death and cancer. Cell Death Differ 2003;10:431-42.
    • (2003) Cell Death Differ , vol.10 , pp. 431-442
    • Oren, M.1
  • 33
    • 0030815967 scopus 로고    scopus 로고
    • A hot spot for p53 mutation in transitional cell carcinoma of the bladder: Clues to the etiology of bladder cancer
    • Xu X, Stower MJ, Reid IN, Garner RC, Burns PA. A hot spot for p53 mutation in transitional cell carcinoma of the bladder: clues to the etiology of bladder cancer. Cancer Epidemiol Biomarkers Prev 1997;6:611-6.
    • (1997) Cancer Epidemiol Biomarkers Prev , vol.6 , pp. 611-616
    • Xu, X.1    Stower, M.J.2    Reid, I.N.3    Garner, R.C.4    Burns, P.A.5
  • 34
    • 0348108078 scopus 로고    scopus 로고
    • Radiation induces p53- dependent cell apoptosis in bladder cancer cells with wild-typep53 but not in p53-mutated bladder cancer cells
    • Hinata N, Shirakawa T, Zhang Z, et al. Radiation induces p53- dependent cell apoptosis in bladder cancer cells with wild-typep53 but not in p53-mutated bladder cancer cells. Urol Res 2003; 31:387-96.
    • (2003) Urol Res , vol.31 , pp. 387-396
    • Hinata, N.1    Shirakawa, T.2    Zhang, Z.3
  • 35
    • 28444487382 scopus 로고    scopus 로고
    • The possible role of TP53 mutation status in the treatment of squamous cell carcinomas of the head and neck (HNSCC) with radiotherapy with different overall treatment times
    • Eriksen JG, Alsner J, Steiniche T, Overgaard J. The possible role of TP53 mutation status in the treatment of squamous cell carcinomas of the head and neck (HNSCC) with radiotherapy with different overall treatment times. Radiother Oncol 2005;76:135-42.
    • (2005) Radiother Oncol , vol.76 , pp. 135-142
    • Eriksen, J.G.1    Alsner, J.2    Steiniche, T.3    Overgaard, J.4
  • 36
    • 15244362062 scopus 로고    scopus 로고
    • P53 abnormalities and outcomes in colorectal cancer: A systematic review
    • Munro AJ, Lain S, Lane DP. P53 abnormalities and outcomes in colorectal cancer: a systematic review. Br J Cancer 2005;92: 434-44.
    • (2005) Br J Cancer , vol.92 , pp. 434-444
    • Munro, A.J.1    Lain, S.2    Lane, D.P.3
  • 37
    • 28944434714 scopus 로고    scopus 로고
    • Association of p53 mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to adjuvant radiotherapy in endometrioid endometrial carcinomas
    • Saffari B, Bernstein L, Hong DC, et al. Association of p53 mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to adjuvant radiotherapy in endometrioid endometrial carcinomas. Int J Gynecol Cancer 2005;15:952-63.
    • (2005) Int J Gynecol Cancer , vol.15 , pp. 952-963
    • Saffari, B.1    Bernstein, L.2    Hong, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.