Reducing effect of a Phaseolus vulgaris dry extract on operant self-administration of a chocolate-flavoured beverage in rats

British Journal of Nutrition

Volumn 104, Issue 5, 2010, Pages 624-628

  MacCioni, Paola ^a   Colombo, Giancarlo ^a   Riva, Antonella ^b   Morazzoni, Paolo ^b   Bombardelli, Ezio ^b   Gessa, Gian Luigi ^a   Carai, Mauro A M ^a  

^a CNR   (Italy)

^b INDENA S P A   (Italy)

Author keywords

Chocolate flavoured beverages; Food intake; Operant self administration; Phaseolus vulgaris dry extract (Beanblock ); Rats

Indexed keywords

PHASEOLUS VULGARIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; ANOREXIGENIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; BEVERAGE; CACAO; CONTROLLED STUDY; DRUG EFFECT; FLUID INTAKE; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PALATABILITY; PHASEOLUS VULGARIS; RAT; REINFORCEMENT; ANIMAL; ANIMAL BEHAVIOR; BEAN; DOSE RESPONSE; DRUG SELF ADMINISTRATION; REWARD; WISTAR RAT;

PHASEOLUS VULGARIS; RATTUS; RODENTIA;

ANIMALS; APPETITE DEPRESSANTS; BEHAVIOR, ANIMAL; BEVERAGES; CACAO; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; PHASEOLUS; PLANT EXTRACTS; RATS; RATS, WISTAR; REINFORCEMENT SCHEDULE; REWARD; SELF ADMINISTRATION;

EID: 77956928616     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114510001017     Document Type: Article

References (15)

1. Obiro WC, Zhang T & Jiang B (2008) The nutraceutical role of the Phaseolus vulgaris a-amylase inhibitor. Br J Nutr 100, 1-12.
2. Pusztai A, Bardocz S & Ewen SWB (2008) Uses of plant lectins in bioscience and biomedicine. Front Biosci 13, 1130-1140.
3. Carai MAM, Fantini N, Loi B, et al. (2009) Potential efficacy of preparations deriving from Phaseolus vulgaris in the control of appetite, energy intake, and carbohydrate metabolism. Diabetes Metab Syn Obes Tar Ther 2, 145-153.
4. Layer P, Carlson GL & Di Magno EP (1985) Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans. Gastroenterology 88, 1895-1902.
5. Boivin M, Zinsmeister AR, Go VL, et al. (1987) Effect of a purified amylase inhibitor on carbohydrate metabolism after a mixed meal in healthy humans. Mayo Clin Proc 62, 249-255.
6. Jain NK, Boivin M, Zinsmeister AR, et al. (1989) Effect of ileal perfusion of carbohydrates and amylase inhibitor on gastrointestinal hormones and emptying. Gastroenterology 96, 377-387.
7. Udani J, Hardy M & Madsen DC (2004) Blocking carbohydrate absorption and weight loss: A clinical trial using Phase 2 brand proprietary fractionated white bean extract. Altern Med Rev 9, 63-69.
8. Udani J & Singh BB (2007) Blocking carbohydrate absorption and weight loss: A clinical trial using a proprietary fractionated white bean extract. Altern Ther Health Med 13, 32-37.
9. Celleno L, Tolaini MV, D'Amore A, et al. (2007) A dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women. Int J Med Sci 4, 45-52.
10. Rondanelli M, Orsini F, Opizzi A, et al. (2009) The effect of 2-mo administration of a Phaseolus vulgaris and Cynara scolymus complex on feeling of satiation in healthy, overweight people. Eur J Obes 2, Suppl. 2, 234.
11. Fantini N, Cabras C, Lobina C, et al. (2009) Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats. J Agric Food Chem 57, 9316-9323.
12. Maccioni P, Pes D, Carai MAM, et al. (2008) Suppression by the cannabinoid CB1 receptor antagonist, rimonabant, of the reinforcing and motivational properties of a chocolate-flavoured beverage in rats. Behav Pharmacol 19, 197-209.
13. Jain NK, Boivin M, Zinsmeister AR, et al. (1991) The ileum and carbohydrate-mediated feedback regulation of postprandial pancreatico-biliary secretion in normal humans. Pancreas 6, 495-505.
14. Tormo MA, Gil-Exojo I, Romero de Tejada A, et al. (2004) Hypoglycaemic and anorexigenic activities of an a-amylase inhibitor from white kidney beans (Phaseolus vulgaris) in Wistar rats. Br J Nutr 92, 785-790.
15. Tormo MA, Gil-Exojo I, Romero de Tejada A, et al. (2006) White bean amylase inhibitor administered orally reduces glycaemia in type 2 diabetic rats. Br J Nutr 96, 539-544.