Robust synthesis of methyl 5-chloro-4-fluoro-1 h -indole-2-carboxylate: A key intermediate in the preparation of an HIV NNRTI candidate

Organic Process Research and Development

Volumn 14, Issue 5, 2010, Pages 1248-1253

  Mayes, Benjamin A ^a   Chaudhuri, Narayan C ^a   Hencken, Christopher P ^a   Jeannot, Frederic ^a   Latham, G Mark ^a   Mathieu, Steven ^a   Mcgarry, F Patrick ^a   Stewart, Alistair J ^a   Wang, Jingyang ^a   Moussa, Adel ^a  

^a Idenix Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE APPROACH; BOC PROTECTION; CHROMATOGRAPHIC ISOLATION; DEPROTECTION; INDOLE-2-CARBOXYLIC ACID; REGIO-SELECTIVE; REVERSE TRANSCRIPTASES; ROBUST SYNTHESIS; SIDE PRODUCTS; SYNTHETIC PREPARATION;

CARBOXYLATION; CARBOXYLIC ACIDS; ESTERIFICATION; ESTERS;

REGIOSELECTIVITY;

EID: 77956925720     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op1001808     Document Type: Article

References (23)

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