The p66shc gene expression in peripheral blood monocytes is increased in patients with coronary artery disease

Clinical Cardiology

Volumn 33, Issue 9, 2010, Pages 548-552

  Noda, Yoshihiro ^a   Yamagishi, Sho Ichi ^a   Matsui, Takanori ^a   Ueda, So ^a   Ueda, Shin Ichiro ^a   Jinnouchi, Yuko ^a   Hirai, Yuji ^a   Imaizumi, Tsutomu ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PROTEIN P66; PROTEIN P66 SHC; PROTEIN SHC; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA; URIC ACID; SHC1 PROTEIN, HUMAN;

AGED; ANGIOCARDIOGRAPHY; ANTIHYPERTENSIVE THERAPY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; JAPANESE; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BLOOD; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; GENETICS; JAPAN; METABOLISM; MONOCYTE; MULTIVARIATE ANALYSIS; REGRESSION ANALYSIS; STATISTICAL MODEL; STATISTICS;

AGED; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; GENE EXPRESSION; HUMANS; JAPAN; LOGISTIC MODELS; MALE; MONOCYTES; MULTIVARIATE ANALYSIS; REGRESSION ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHC SIGNALING ADAPTOR PROTEINS; STATISTICS AS TOPIC;

EID: 77956909543     PISSN: 01609289     EISSN: 19328737     Source Type: Journal    
DOI: 10.1002/clc.20761     Document Type: Article

References (15)

1. Briasoulis A, Tousoulis D, Antoniades C, et al. The oxidative stress menace to coronary vasculature: any place for antioxidants? Curr Pharm Des. 2009;15:3078-3090.
2. Victor VM, Rocha M, Solá E, et al. Oxidative stress, endothelial dysfunction and atherosclerosis. Curr Pharm Des. 2009;15:2988-3002.
3. Yamagishi S, Nakamura K, Matsui T. Role of oxidative stress in the development of vascular injury and its therapeutic intervention by nifedipine. Curr Med Chem. 2008;15:172-177. (Pubitemid 351234620)
4. Antonopoulos AS, Antoniades C, Tousoulis D, et al. Novel therapeutic strategies targeting vascular redox in human atherosclerosis. Recent Pat Cardiovasc Drug Discov. 2009;4:76-87.
5. Francia P, Cosentino F, Schiavoni M, et al. p66(Shc) protein, oxidative stress, and cardiovascular complications of diabetes: the missing link. J Mol Med. 2009;87:885-891.
6. Pellegrini M, Baldari CT. Apoptosis and oxidative stress-related diseases: the p66Shc connection. Curr Mol Med. 2009;9:392-398.
7. Francia P, delli Gatti C, Bachschmid M, et al. Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation. 2004;110:2889-2895.
8. Napoli C, Martin-Padura I, de Nigris F, et al. Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet. Proc Natl Acad Sci U S A. 2003;100:2112-2116. (Pubitemid 36254582)
9. Martin-Padura I, de Nigris F, Migliaccio E, et al. p66Shc deletion confers vascular protection in advanced atherosclerosis in hypercholesterolemic apolipoprotein E knockout mice. Endothelium. 2008;15:276-287.
10. Tahara N, Kai H, Yamagishi S, et al. Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome. J Am Coll Cardiol. 2007;49:1533-1539.
11. Imai E, Horio M, Nitta K, et al. Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease. Clin Exp Nephrol. 2007;11:41-50. (Pubitemid 46474965)
12. Miura J, Uchigata Y, Yamamoto Y, et al. AGE down-regulation of monocyte RAGE expression and its association with diabetic complications in type 1 diabetes. J Diabetes Complications. 2004;18:53-59.
13. Wilson HM, Barker RN, Erwig LP. Macrophages: promising targets for the treatment of atherosclerosis. Curr Vasc Pharmacol. 2009;7:234-243.
14. Saha P, Modarai B, Humphries J, et al. Themonocyte/macrophage as a therapeutic target in atherosclerosis. Curr Opin Pharmacol. 2009;9:109-118.
15. shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress. J Clin Endocrinol Metab. 2005;90:1130-1136.