Kaposi Sarcoma (KS) - Associated herpesvirus microRNA sequence analysis and KS risk in a European AIDS-KS case control study

Journal of Infectious Diseases

Volumn 202, Issue 7, 2010, Pages 1126-1135

  Marshall, Vickie ^a   Martró, Elisa ^d,e   Labo, Nazzarena ^a   Ray, Alex ^a   Wang, Dian ^a   Mbisa, Georginia ^a   Bagni, Rachel K ^b   Volfovsky, Natalia ^c   Casabona, Jordi ^d   Whitby, Denise ^a  

^a AIDS and Cancer Virus Program   (United States)

^b Advanced Technology Program   (United States)

^c SAIC FREDERICK INC   (United States)

^d HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^e CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; VIRUS DNA; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CANCER RISK; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; INFECTION RISK; KAPOSI SARCOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS LOAD; BLOOD; CHEMISTRY; GENETIC POLYMORPHISM; GENETICS; METHODOLOGY; MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; RISK FACTOR; VIROLOGY;

ACQUIRED IMMUNODEFICIENCY SYNDROME; CASE-CONTROL STUDIES; DNA, VIRAL; HERPESVIRUS 8, HUMAN; HUMANS; LEUKOCYTES, MONONUCLEAR; MICRORNAS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RISK FACTORS; SARCOMA, KAPOSI; SEQUENCE ANALYSIS; VIRAL LOAD;

EID: 77956897797     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/656045     Document Type: Article

References (29)

1. Chang Y, Cesarman E, Pessin MS, et al. Identification of herpesviruslike DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994; 266:1865-1869.
2. Engels EA, Pfeiffer RM, Goedert JJ, et al. Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS 2006; 20: 1645-1654.
3. Clifford GM, Polesel J, Rickenbach M, et al. Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy. J Natl Cancer Inst 2005; 97:425-432. (Pubitemid 40528605)
4. Maurer T, Ponte M, Leslie K. HIV-associated Kaposi's sarcoma with a high CD4 count and a low viral load. N Engl J Med 2007; 357: 1352-1353. (Pubitemid 47481472)
5. Krown SE, Lee JY, Dittmer DP. More on HIV-associated Kaposi's sarcoma. N Engl J Med 2008; 358:535-536; author reply, 536.
6. Cook PM, Whitby D, Calabro ML, et al. Variability and evolution of Kaposi's sarcoma-associated herpesvirus in Europe and Africa. International Collaborative Group. AIDS 1999; 13:1165-1176.
7. Meng YX, Spira TJ, Bhat GJ, et al. Individuals from North America, Australasia, and Africa are infected with four different genotypes of human herpesvirus 8. Virology 1999; 261:106-119.
8. Zong JC, Ciufo DM, Alcendor DJ, et al. High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma- associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations. J Virol 1999; 73:4156-4170.
9. Mancuso R, Biffi R, Valli M, et al. HHV8 a subtype is associated with rapidly evolving classic Kaposi's sarcoma. J Med Virol 2008; 80:2153-2160.
10. Pfeffer S, Zavolan M, Grasser FA, et al. Identification of virus-encoded microRNAs. Science 2004; 304:734-736.
11. Samols MA, Hu J, Skalsky RL, Renne R. Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus. J Virol 2005; 79:9301-9305. (Pubitemid 40934841)
12. Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci U S A 2005; 102:5570-5575.
13. Marshall V, Parks T, Bagni R, et al. Conservation of virally encoded microRNAs in Kaposi sarcoma-associated herpesvirus in primary effusion lymphoma cell lines and in patients with Kaposi sarcoma or multicentric Castleman disease. J Infect Dis 2007; 195:645-659.
14. Martro E, Esteve A, Schulz TF, et al. Risk factors for human herpesvirus 8 infection and AIDS-associated Kaposi's sarcoma among men who have sex with men in a European multicentre study. Int J Cancer 2007; 120:1129-1135. (Pubitemid 46214317)
15. Gaya A, Esteve A, Casabona J, et al. Amino acid residue at position 13 in HLA-DR beta chain plays a critical role in the development of Kaposi's sarcoma in AIDS patients. AIDS 2004; 18:199-204.
16. de Sanjose S, Marshall V, Sola J, et al. Prevalence of Kaposi's sarcoma-associated herpesvirus infection in sex workers and women from the general population in Spain. Int J Cancer 2002; 98:155-158.
17. Engels EA, Atkinson JO, Graubard BI, et al. Risk factors for human herpesvirus 8 infection among adults in the United States and evidence for sexual transmission. J Infect Dis 2007; 196:199-207.
18. Yuan CC, Miley W, Waters D. A quantification of human cells using an ERV-3 real time PCR assay. J Virol Methods 2001; 91:109-117. (Pubitemid 32119328)
19. Whitby D, Marshall VA, Bagni RK, et al. Genotypic characterization of Kaposi's sarcoma-associated herpesvirus in asymptomatic infected subjects from isolated populations. J Gen Virol 2004; 85:155-163.
20. Subbiah M, Srinivasan MR. Classifiction of 2x2 sparse data sets with zero cells. Statistics & Probability Letters 2008; 78:3212-3215.
21. Whitby D, Howard MR, Tenant-Flowers M, et al. Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet 1995; 346:799-802.
22. Duan R, Pak C, Jin P. Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet 2007; 16:1124-1131.
23. Borel C, Antonarakis SE. Functional genetic variation of humanmiRNAs and phenotypic consequences. Mamm Genome 2008; 19:503-509.
24. Gottwein E, Cai X, Cullen BR. A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing. J Virol 2006; 80:5321-5326. (Pubitemid 43752777)
25. Wilkinson J, Cope A, Gill J, et al. Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)- specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy. J Virol 2002; 76:2634-2640.
26. Bourboulia D, Aldam D, Lagos D, et al. Short- and long-term effects of highly active antiretroviral therapy on Kaposi sarcoma-associated herpesvirus immune responses and viraemia. AIDS 2004; 18:485-493.
27. Guihot A, Dupin N, Marcelin AG, et al. Low T cell responses to human herpesvirus 8 in patients with AIDS-related and classic Kaposi sarcoma. J Infect Dis 2006; 194:1078-1088.
28. Qin Z, Kearney P, Plaisance K, Parsons CH. Pivotal advance: Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded microRNA specifically induce IL-6 and IL-10 secretion by macrophages and monocytes. J Leukoc Biol 2010; 87(1):25-34.
29. Bellare P, Ganem D. Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host Microbe 2009; 6:570-575.