메뉴 건너뛰기




Volumn 185, Issue 4, 2010, Pages 2004-2008

Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses

Author keywords

[No Author keywords available]

Indexed keywords

RAPAMYCIN; T LYMPHOCYTE ANTIGEN; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; L SELECTIN;

EID: 77956893188     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1001176     Document Type: Article
Times cited : (101)

References (19)
  • 3
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger, S., R. Loewith, and M. N. Hall. 2006. TOR signaling in growth and metabolism. Cell 124: 471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 4
    • 52549127241 scopus 로고    scopus 로고
    • Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
    • Cao, W., S. Manicassamy, H. Tang, S. P. Kasturi, A. Pirani, N. Murthy, and B. Pulendran. 2008. Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat. Immunol. 9: 1157-1164.
    • (2008) Nat. Immunol. , vol.9 , pp. 1157-1164
    • Cao, W.1    Manicassamy, S.2    Tang, H.3    Kasturi, S.P.4    Pirani, A.5    Murthy, N.6    Pulendran, B.7
  • 6
    • 41149113441 scopus 로고    scopus 로고
    • The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
    • Haxhinasto, S., D. Mathis, and C. Benoist. 2008. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J. Exp. Med. 205: 565-574.
    • (2008) J. Exp. Med. , vol.205 , pp. 565-574
    • Haxhinasto, S.1    Mathis, D.2    Benoist, C.3
  • 8
    • 0029003462 scopus 로고
    • Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity
    • Shen, H., M. K. Slifka, M. Matloubian, E. R. Jensen, R. Ahmed, and J. F. Miller. 1995. Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity. Proc. Natl. Acad. Sci. USA 92: 3987-3991.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3987-3991
    • Shen, H.1    Slifka, M.K.2    Matloubian, M.3    Jensen, E.R.4    Ahmed, R.5    Miller, J.F.6
  • 9
    • 0142122407 scopus 로고    scopus 로고
    • Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection
    • Ehst, B. D., E. Ingulli, and M. K. Jenkins. 2003. Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection. Am. J. Transplant. 3: 1355-1362.
    • (2003) Am. J. Transplant. , vol.3 , pp. 1355-1362
    • Ehst, B.D.1    Ingulli, E.2    Jenkins, M.K.3
  • 10
    • 33847152240 scopus 로고    scopus 로고
    • Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation
    • Ford, M. L., B. H. Koehn, M. E.Wagener, W. Jiang, S. Gangappa, T. C. Pearson, and C. P. Larsen. 2007. Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation. J. Exp. Med. 204: 299-309.
    • (2007) J. Exp. Med. , vol.204 , pp. 299-309
    • Ford, M.L.1    Koehn, B.H.2    Wagener, M.E.3    Jiang, W.4    Gangappa, S.5    Pearson, T.C.6    Larsen, C.P.7
  • 12
    • 72449147738 scopus 로고    scopus 로고
    • The multifunctional role of mTOR in innate immunity: Implications for transplant immunity
    • Säemann, M. D., M. Haidinger, M. Hecking, W. H. Hörl, and T. Weichhart. 2009. The multifunctional role of mTOR in innate immunity: implications for transplant immunity. Am. J. Transplant. 9: 2655-2661.
    • (2009) Am. J. Transplant. , vol.9 , pp. 2655-2661
    • Säemann, M.D.1    Haidinger, M.2    Hecking, M.3    Hörl, W.H.4    Weichhart, T.5
  • 13
    • 34249805413 scopus 로고    scopus 로고
    • Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance
    • Turnquist, H. R., G. Raimondi, A. F. Zahorchak, R. T. Fischer, Z. Wang, and A. W. Thomson. 2007. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. J. Immunol. 178: 7018-7031.
    • (2007) J. Immunol. , vol.178 , pp. 7018-7031
    • Turnquist, H.R.1    Raimondi, G.2    Zahorchak, A.F.3    Fischer, R.T.4    Wang, Z.5    Thomson, A.W.6
  • 14
    • 76249084928 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients
    • Raimondi, G., T. L. Sumpter, B. M. Matta, M. Pillai, N. Corbitt, Y. Vodovotz, Z. Wang, and A. W. Thomson. 2010. Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients. J. Immunol. 184: 624-636.
    • (2010) J. Immunol. , vol.184 , pp. 624-636
    • Raimondi, G.1    Sumpter, T.L.2    Matta, B.M.3    Pillai, M.4    Corbitt, N.5    Vodovotz, Y.6    Wang, Z.7    Thomson, A.W.8
  • 15
    • 56149110848 scopus 로고    scopus 로고
    • MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection
    • Rahman, A. H., W. Cui, D. F. Larosa, D. K. Taylor, J. Zhang, D. R. Goldstein, E. J. Wherry, S. M. Kaech, and L. A. Turka. 2008. MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection. J. Immunol. 181: 3804-3810.
    • (2008) J. Immunol. , vol.181 , pp. 3804-3810
    • Rahman, A.H.1    Cui, W.2    Larosa, D.F.3    Taylor, D.K.4    Zhang, J.5    Goldstein, D.R.6    Wherry, E.J.7    Kaech, S.M.8    Turka, L.A.9
  • 18
    • 0036785554 scopus 로고    scopus 로고
    • T cells primed by Leishmania major infection cross-react with alloantigens and alter the course of allograft rejection
    • Pantenburg, B., F. Heinzel, L. Das, P. S. Heeger, and A. Valujskikh. 2002. T cells primed by Leishmania major infection cross-react with alloantigens and alter the course of allograft rejection. J. Immunol. 169: 3686-3693.
    • (2002) J. Immunol. , vol.169 , pp. 3686-3693
    • Pantenburg, B.1    Heinzel, F.2    Das, L.3    Heeger, P.S.4    Valujskikh, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.