Measurement of relative cerebral blood volume using BOLD contrast and mild hypoxic hypoxia

Magnetic Resonance Imaging

Volumn 28, Issue 8, 2010, Pages 1129-1134

  Wise, Richard G ^a,b   Pattinson, Kyle T S ^a   Bulte, Daniel P ^a   Rogers, Richard ^a   Tracey, Irene ^a   Matthews, Paul M ^a,c   Jezzard, Peter ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

BOLD; Cerebral blood volume; FMRI; Hypoxia

Indexed keywords

ADULT; ARTERIAL OXYGEN SATURATION; ARTICLE; BLOOD OXYGENATION LEVEL DEPENDENT IMAGING; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; BRAIN PERFUSION; CONTROLLED STUDY; END TIDAL CARBON DIOXIDE TENSION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HUMAN; HYPOXIA; MALE; PRIORITY JOURNAL; SIGNAL DETECTION; WHITE MATTER;

ADULT; ANOXIA; BLOOD VOLUME; BRAIN; BRAIN MAPPING; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PERFUSION; REGRESSION ANALYSIS;

EID: 77956874039     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2010.06.002     Document Type: Article

References (30)

1. Sourbron S., Ingrisch M., Siefert A., Reiser M., Herrmann K. Quantification of cerebral blood flow, cerebral blood volume, and blood-brain-barrier leakage with DCE-MRI. Magn Reson Med 2009, 62(1):205-217.
2. Johnson G., Wetzel S.G., Cha S., Babb J., Tofts P.S. Measuring blood volume and vascular transfer constant from dynamic, T(2)*-weighted contrast-enhanced MRI. Magn Reson Med 2004, 51(5):961-968.
3. Kuppusamy K., Lin W., Cizek G.R., Haacke E.M. In vivo regional cerebral blood volume: quantitative assessment with 3D T1-weighted pre- and postcontrast MR imaging. Radiology 1996, 201(1):106-112.
4. Rosen B.R., Belliveau J.W., Vevea J.M., Brady T.J. Perfusion imaging with NMR contrast agents. Magn Reson Med 1990, 14(2):249-265.
5. Lu H., Golay X., Pekar J.J., Van Zijl P.C. Functional magnetic resonance imaging based on changes in vascular space occupancy. Magn Reson Med 2003, 50(2):263-274.
6. van Zijl P.C., Eleff S.M., Ulatowski J.A., et al. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging. Nat Med 1998, 4(2):159-167.
7. Ulatowski J.A., Oja J.M., Suarez J.I., Kauppinen R.A., Traystman R.J., van Zijl P.C. In vivo determination of absolute cerebral blood volume using hemoglobin as a natural contrast agent: an MRI study using altered arterial carbon dioxide tension. J Cereb Blood Flow Metab 1999, 19(7):809-817.
8. Bulte D., Chiarelli P., Wise R., Jezzard P. Measurement of cerebral blood volume in humans using hyperoxic MRI contrast. J Magn Reson Imaging 2007, 26(4):894-899.
9. Rostrup E., Larsson H.B., Toft P.B., Garde K., Henriksen O. Signal changes in gradient echo images of human brain induced by hypo- and hyperoxia. NMR Biomed 1995, 8(1):41-47.
10. Ho Y.C., Vidyasagar R., Shen Y., Balanos G.M., Golay X., Kauppinen R.A. The BOLD response and vascular reactivity during visual stimulation in the presence of hypoxic hypoxia. NeuroImage 2008, 41(2):179-188.
11. Rostrup E., Larsson H.B., Born A.P., Knudsen G.M., Paulson O.B. Changes in BOLD and ADC weighted imaging in acute hypoxia during sea-level and altitude adapted states. NeuroImage 2005, 28(4):947-955.
12. Gupta A.K., Menon D.K., Czosnyka M., Smielewski P., Jones J.G. Thresholds for hypoxic cerebral vasodilation in volunteers. Anesth Analg 1997, 85(4):817-820.
13. Emoto S.E., Kintner D., Feyzi J.M., Gilboe D.D. Relating cerebral ischemia and hypoxia to insult intensity. J Neurochem 1988, 50(6):1952-1958.
14. 2 in spontaneously breathing animals. NeuroImage 2005, 25(3):850-858.
15. Lin W., Paczynski R.P., Celik A., Kuppusamy K., Hsu C.Y., Powers W.J. Experimental hypoxemic hypoxia: changes in R2* of brain parenchyma accurately reflect the combined effects of changes in arterial and cerebral venous oxygen saturation. Magn Reson Med 1998, 39(3):474-481.
16. Ogawa S., Menon R.S., Tank D.W., et al. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model. Biophys J 1993, 64(3):803-812.
17. Buxton R.B., Uludag K., Dubowitz D.J., Liu T.T. Modeling the hemodynamic response to brain activation. NeuroImage 2004, 23(Suppl 1):S220-S233.
18. Wong E.C., Buxton R.B., Frank L.R. Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II). Magn Reson Med 1998, 39(5):702-708.
19. Luh W.M., Wong E.C., Bandettini P.A., Hyde J.S. QUIPSS II with thin-slice TI1 periodic saturation: a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling. Magn Reson Med 1999, 41(6):1246-1254.
20. Pattinson K.T., Bowes M., Wise R.G., Parkes M.J., Morrell M.J. Evaluation of a non-invasive method of assessing opioid induced respiratory depression. Anaesthesia 2005, 60(5):426-432.
21. 2 in men. J Appl Physiol 1990, 68(4):1727-1731.
22. Jenkinson M., Bannister P., Brady M., Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage 2002, 17(2):825-841.
23. Zhang Y., Brady M., Smith S. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imaging 2001, 20(1):45-57.
24. Woolrich M.W., Ripley B.D., Brady M., Smith S.M. Temporal autocorrelation in univariate linear modeling of FMRI data. NeuroImage 2001, 14(6):1370-1386.
25. 2 induced increase in cerebral perfusion. NMR Biomed 1994, 7(1-2):29-34.
26. Wise R.G., Ide K., Poulin M.J., Tracey I. Resting fluctuations in arterial carbon dioxide induce significant low frequency variations in BOLD signal. NeuroImage 2004, 21(4):1652-1664.
27. Newman G.C., Delucia-Deranja E., Tudorica A., Hospod F.E., Patlak C.S. Cerebral blood volume measurements by T*2-weighted MRI and contrast infusion. Magn Reson Med 2003, 50(4):844-855.
28. Mintun M.A., Lundstrom B.N., Snyder A.Z., Vlassenko A.G., Shulman G.L., Raichle M.E. Blood flow and oxygen delivery to human brain during functional activity: theoretical modeling and experimental data. Proc Natl Acad Sci U S A 2001, 98(12):6859-6864.
29. Lu H., Ge Y. Quantitative evaluation of oxygenation in venous vessels using T2-relaxation-under-spin-tagging MRI. Magn Reson Med 2008, 60(2):357-363.
30. An H., Lin W. Cerebral venous and arterial blood volumes can be estimated separately in humans using magnetic resonance imaging. Magn Reson Med 2002, 48(4):583-588.