Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements

PLoS Biology

Volumn 8, Issue 8, 2010, Pages 55-56

  Boettcher, Jan Peter ^a   Kirchner, Marieluise ^a,c   Churin, Yuri ^a,d   Kaushansky, Alexis ^b   Pompaiah, Malvika ^a   Thorn, Hans ^a,e   Brinkmann, Volker ^a   MacBeath, Gavin ^b   Meyer, Thomas F ^a  

^a MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^b HARVARD UNIVERSITY   (United States)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d JUSTUS LIEBIG UNIVERSITY   (Germany)

^e Carl Zeiss AG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHOTYROSINE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VAV2 PROTEIN; RHOA PROTEIN, HUMAN; TYROSINE; VAV PROTEIN; VAV2 PROTEIN, HUMAN;

ARTICLE; BACTERIUM PILUS; CONTROLLED STUDY; CYTOSKELETON; ENTEROPATHOGENIC ESCHERICHIA COLI; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; INTERNALIZATION; NEISSERIA GONORRHOEAE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; EPITHELIUM CELL; FIMBRIA; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEISSERIA GONORRHOEAE;

CAVEOLIN 1; CELL LINE, TUMOR; CYTOSKELETON; EPITHELIAL CELLS; FIMBRIAE, BACTERIAL; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; NEISSERIA GONORRHOEAE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-VAV; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TYROSINE;

EID: 77956834144     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1000457     Document Type: Article

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