Dabigatran offers the simplest solution for thromboprophylaxis after orthopaedic surgery in patients allergic to low-molecular-weight heparins

British Journal of Haematology

Volumn 151, Issue 1, 2010, Pages 84-85

  Garcia Ortega, Pilar ^a   Asencio, Jordi ^a  

^a HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

dabigatran; drug allergy; heparin allergy; heparin induced; venous thrombosis

Indexed keywords

BEMIPARIN; DABIGATRAN; DALTEPARIN; DOXAZOSIN; ENOXAPARIN; FONDAPARINUX; LOW MOLECULAR WEIGHT HEPARIN; MEPIRODIPINE; TORASEMIDE; VALSARTAN; ANTICOAGULANT AGENT; BENZIMIDAZOLE DERIVATIVE; DABIGATRAN ETEXILATE; PYRIDINE DERIVATIVE;

AGED; CASE REPORT; CROSS REACTION; DEEP VEIN THROMBOSIS; DRUG HYPERSENSITIVITY; FEMALE; HUMAN; KNEE ARTHROPLASTY; LETTER; ORTHOPEDIC SURGERY; PRIORITY JOURNAL; SKIN TEST; DRUG ERUPTIONS; POSTOPERATIVE COMPLICATIONS; VENOUS THROMBOSIS; VERY ELDERLY;

AGED, 80 AND OVER; ANTICOAGULANTS; ARTHROPLASTY, REPLACEMENT, KNEE; BENZIMIDAZOLES; DRUG ERUPTIONS; FEMALE; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; POSTOPERATIVE COMPLICATIONS; PYRIDINES; VENOUS THROMBOSIS;

EID: 77956817312     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08290.x     Document Type: Letter

References (6)

1. Ammollo, C.T., Semeraro, F., Incampo, F., Semeraro, N. Colucci, M. (2010) Dabigatran enhances clot susceptibility to fibrinolysis by TAFI-dependent and independent mechanisms. Journal of Thrombosis and Haemostasis, 8, 790 798.
2. Bircher, A.J., Harr, T., Hohenstein, L. Tsakiris, D.A. (2006) Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options. Allergy, 61, 1432 1440.
3. Grims, R.H., Weger, W., Reiter, H., Arbab, E., Kränke, B. Aberer, W. (2007) Delayed-type hypersensitivity to low molecular weight heparins and heparinoids: cross-reactivity does not depend on molecular weight. British Journal of Dermatology, 157, 514 517.
4. Seitz, C.S., Brocker, E.B. Trautmann, A. (2008) Management of allergy to heparins in postoperative care: subcutaneous allergy and intravenous tolerance. Dermatology Online Journal, 14, 4.
5. Trautmann, A. Seitz, C.S. (2009) Heparin allergy: delayed-type non-IgE-mediated allergic hypersensitivity to subcutaneous heparin injection. Immunology and Allergy Clinics of North America, 29, 469 480.
6. Wolowacz, S.E., Roskell, N.S., Plumb, J.M., Caprini, J.A. Eriksson, B.I. (2009) Efficacy and safety of dabigatran etexilate for the prevention of venous thromboembolism following total hip or knee arthroplasty. A meta-analysis. Thrombosis and Haemostasis, 101, 77 85.