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Volumn 118, Issue 9, 2010, Pages 1286-1291

Are environmental levels of bisphenol A associated with reproductive function in fertile men?

Author keywords

Bisphenol A; Endocrine disruptors; Male hormones; Semen quality; Xenoestrogens

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ANDROGEN; CREATININE; ESTRADIOL; FOLLITROPIN; INHIBIN B; LUTEINIZING HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

EID: 77956791365     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002037     Document Type: Article
Times cited : (194)

References (44)
  • 1
    • 0842313074 scopus 로고    scopus 로고
    • Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells
    • Akingbemi BT, Sottas CM, Koulova AI, Klinefelter GR, Hardy MP. 2004. Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells. Endocrinology 145:592-603.
    • (2004) Endocrinology , vol.145 , pp. 592-603
    • Akingbemi, B.T.1    Sottas, C.M.2    Koulova, A.I.3    Klinefelter, G.R.4    Hardy, M.P.5
  • 2
  • 4
    • 34548752809 scopus 로고    scopus 로고
    • Increased frequency of reproductive health problems among fathers of boys with hypospadias
    • Asklund C, Jørgensen N, Skakkebaek NE, Jensen TK. 2007. Increased frequency of reproductive health problems among fathers of boys with hypospadias. Hum Reprod 22:2639-2646.
    • (2007) Hum Reprod , vol.22 , pp. 2639-2646
    • Asklund, C.1    Jørgensen, N.2    Skakkebaek, N.E.3    Jensen, T.K.4
  • 5
    • 27944503563 scopus 로고    scopus 로고
    • A study of finger lengths, semen quality and sex hormones in 360 young men from the general Danish population
    • Bang AK, Carlsen E, Holm M, Petersen JH, Skakkebaek NE, Jørgensen N. 2005. A study of finger lengths, semen quality and sex hormones in 360 young men from the general Danish population. Hum Reprod 20:3109-3113.
    • (2005) Hum Reprod , vol.20 , pp. 3109-3113
    • Bang, A.K.1    Carlsen, E.2    Holm, M.3    Petersen, J.H.4    Skakkebaek, N.E.5    Jørgensen, N.6
  • 6
    • 33749540083 scopus 로고    scopus 로고
    • Seasonal variation of estradiol, follicle stimulating hormone, and dehydroepiandrosterone sulfate in women and men
    • Bjørnerem A, Straume B, Oian P, Berntsen GK. 2006. Seasonal variation of estradiol, follicle stimulating hormone, and dehydroepiandrosterone sulfate in women and men. J Clin Endocrinol Metab 91:3798-3802.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3798-3802
    • Bjørnerem, A.1    Straume, B.2    Oian, P.3    Berntsen, G.K.4
  • 7
    • 3042856187 scopus 로고    scopus 로고
    • Standardized methods for semen evaluation in a multicenter research study
    • Brazil C, Swan SH, Drobnis EZ, Liu F, Wang C, Redmon JB, et al. 2004. Standardized methods for semen evaluation in a multicenter research study. J Androl 25:635-644.
    • (2004) J Androl , vol.25 , pp. 635-644
    • Brazil, C.1    Swan, S.H.2    Drobnis, E.Z.3    Liu, F.4    Wang, C.5    Redmon, J.B.6
  • 8
    • 0020635522 scopus 로고
    • Loss of circadian rhythmicity in blood testosterone levels with aging in normal men
    • Bremner WJ, Vitiello MV, Prinz PN. 1983. Loss of circadian rhythmicity in blood testosterone levels with aging in normal men. J Clin Endocrinol Metab 56:1278-1281.
    • (1983) J Clin Endocrinol Metab , vol.56 , pp. 1278-1281
    • Bremner, W.J.1    Vitiello, M.V.2    Prinz, P.N.3
  • 9
    • 39749187628 scopus 로고    scopus 로고
    • Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004
    • Calafat AM, Ye X, Wong LY, Reidy JA, Needham LL. 2008. Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004. Environ Health Perspect 116:39-44.
    • (2008) Environ Health Perspect , vol.116 , pp. 39-44
    • Calafat, A.M.1    Ye, X.2    Wong, L.Y.3    Reidy, J.A.4    Needham, L.L.5
  • 10
    • 0026657024 scopus 로고
    • Evidence for decreasing quality of semen during the past 50 years
    • Carlsen E, Giwercman A, Keiding N, Skakkebaek NE. 1992. Evidence for decreasing quality of semen during the past 50 years. BMJ 305:609-613.
    • (1992) BMJ , vol.305 , pp. 609-613
    • Carlsen, E.1    Giwercman, A.2    Keiding, N.3    Skakkebaek, N.E.4
  • 11
    • 77956831317 scopus 로고    scopus 로고
    • CDC (Centers for Disease Control and Prevention). NHANES 2003-2004 Laboratory Files, Lab 24, Atlanta, GA:CDC. Available:, accessed 2 August 2010
    • CDC (Centers for Disease Control and Prevention). 2008. NHANES 2003-2004 Laboratory Files, Lab 24: Environmental Phenols. Atlanta, GA:CDC. Available: http://www.cdc.gov/nchs/nhanes/nhanes2003-2004/lab03_04.htm [accessed 2 August 2010].
    • (2008) Environmental Phenols
  • 12
    • 0037793319 scopus 로고    scopus 로고
    • Diurnal rhythms of serum total, free and bioavailable testosterone and of SHBG in middle-aged men compared with those in young men
    • Diver MJ, Imtiaz KE, Ahmad AM, Vora JP, Fraser WD. 2003. Diurnal rhythms of serum total, free and bioavailable testosterone and of SHBG in middle-aged men compared with those in young men. Clin Endocrinol (Oxf) 58:710-717.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , pp. 710-717
    • Diver, M.J.1    Imtiaz, K.E.2    Ahmad, A.M.3    Vora, J.P.4    Fraser, W.D.5
  • 13
    • 0026007087 scopus 로고
    • Sex steroid control of gonadotropin secretion in the human male. II. Effects of estradiol administration in normal and gonadotropin-releasing hormone-deficient men
    • Finkelstein JS, O'Dea LS, Whitcomb RW, Crowley WF Jr. 1991. Sex steroid control of gonadotropin secretion in the human male. II. Effects of estradiol administration in normal and gonadotropin-releasing hormone-deficient men. J Clin Endocrinol Metab 73:621-628.
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 621-628
    • Finkelstein, J.S.1    O'Dea, L.S.2    Whitcomb, R.W.3    Crowley Jr., W.F.4
  • 15
    • 0036367511 scopus 로고    scopus 로고
    • Urinary bisphenol A and plasma hormone concentrations in male workers exposed to bisphenol A diglycidyl ether and mixed organic solvents
    • Hanaoka T, Kawamura N, Hara K, Tsugane S. 2002. Urinary bisphenol A and plasma hormone concentrations in male workers exposed to bisphenol A diglycidyl ether and mixed organic solvents. Occup Environ Med 59:625-628.
    • (2002) Occup Environ Med , vol.59 , pp. 625-628
    • Hanaoka, T.1    Kawamura, N.2    Hara, K.3    Tsugane, S.4
  • 16
    • 21244482596 scopus 로고    scopus 로고
    • Adverse effects of environmental toxicants, octylphenol and bisphenol A, on male reproductive functions in pubertal rats
    • Herath CB, Jin W, Watanabe G, Arai K, Suzuki AK, Taya K. 2004. Adverse effects of environmental toxicants, octylphenol and bisphenol A, on male reproductive functions in pubertal rats. Endocrine 25:163-172.
    • (2004) Endocrine , vol.25 , pp. 163-172
    • Herath, C.B.1    Jin, W.2    Watanabe, G.3    Arai, K.4    Suzuki, A.K.5    Taya, K.6
  • 17
    • 0025261744 scopus 로고
    • Estimation of average concentration in the presence of non-detectable values
    • Hornung RW, Reed LD. 1990. Estimation of average concentration in the presence of non-detectable values. Appl Occup Environ Hyg 5:46-51.
    • (1990) Appl Occup Environ Hyg , vol.5 , pp. 46-51
    • Hornung, R.W.1    Reed, L.D.2
  • 18
    • 40349094571 scopus 로고    scopus 로고
    • Low dose mixture effects of endocrine disrupters: Implications for risk assessment and epidemiology
    • Kortenkamp A. 2008. Low dose mixture effects of endocrine disrupters: implications for risk assessment and epidemiology. Int J Androl 31:233-240.
    • (2008) Int J Androl , vol.31 , pp. 233-240
    • Kortenkamp, A.1
  • 19
    • 0041380903 scopus 로고    scopus 로고
    • Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor
    • Lee HJ, Chattopadhyay S, Gong EY, Ahn RS, Lee K. 2003. Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor. Toxicol Sci 75:40-46.
    • (2003) Toxicol Sci , vol.75 , pp. 40-46
    • Lee, H.J.1    Chattopadhyay, S.2    Gong, E.Y.3    Ahn, R.S.4    Lee, K.5
  • 20
    • 74549204438 scopus 로고    scopus 로고
    • Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction
    • Li D, Zhou Z, Qing D, He Y, Wu T, Miao M, et al. 2010. Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction. Hum Reprod 25(2):519-527.
    • (2010) Hum Reprod , vol.25 , Issue.2 , pp. 519-527
    • Li, D.1    Zhou, Z.2    Qing, D.3    He, Y.4    Wu, T.5    Miao, M.6
  • 21
    • 33745899960 scopus 로고    scopus 로고
    • Endocrine disruptors and reproductive health: The case of bisphenol-A
    • Maffini MV, Rubin BS, Sonnenschein C, Soto AM. 2006. Endocrine disruptors and reproductive health: the case of bisphenol-A. Mol Cell Endocrinol 254-255:179-186.
    • (2006) Mol Cell Endocrinol , vol.254-255 , pp. 179-186
    • Maffini, M.V.1    Rubin, B.S.2    Sonnenschein, C.3    Soto, A.M.4
  • 23
    • 77249178806 scopus 로고    scopus 로고
    • Urinary bisphenol A concentrations in relation to serum thyroid and reproductive hormone levels in men from an infertility clinic
    • doi: 10.1021/es9028292 [Online 23 December 2009]
    • Meeker JD, Calafat AM, Hauser R. 2010. Urinary bisphenol A concentrations in relation to serum thyroid and reproductive hormone levels in men from an infertility clinic. Environ Sci Technol 44:1458-1463; doi: 10.1021/es9028292 [Online 23 December 2009].
    • (2010) Environ Sci Technol , vol.44 , pp. 1458-1463
    • Meeker, J.D.1    Calafat, A.M.2    Hauser, R.3
  • 24
    • 0030893546 scopus 로고    scopus 로고
    • Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol
    • Nagel SC, vom Saal FS, Thayer KA, Dhar MG, Boechler M, Welshons WV. 1997. Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. Environ Health Perspect 105:70-76.
    • (1997) Environ Health Perspect , vol.105 , pp. 70-76
    • Nagel, S.C.1    vom Saal, F.S.2    Thayer, K.A.3    Dhar, M.G.4    Boechler, M.5    Welshons, W.V.6
  • 25
    • 0033819596 scopus 로고    scopus 로고
    • Localization of androgen and estrogen receptors in rat and primate tissues
    • Pelletier G. 2000. Localization of androgen and estrogen receptors in rat and primate tissues. Histol Histopathol 15:1261-1270.
    • (2000) Histol Histopathol , vol.15 , pp. 1261-1270
    • Pelletier, G.1
  • 27
    • 70349984500 scopus 로고    scopus 로고
    • Neonatal exposure of male rats to bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis
    • Salian S, Doshi T, Vanage G. 2009a. Neonatal exposure of male rats to bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis. Toxicology 265:56-67.
    • (2009) Toxicology , vol.265 , pp. 56-67
    • Salian, S.1    Doshi, T.2    Vanage, G.3
  • 28
    • 70449108111 scopus 로고    scopus 로고
    • Perinatal exposure of rats to bisphenol A affects the fertility of male offspring
    • Salian S, Doshi T, Vanage G. 2009b. Perinatal exposure of rats to bisphenol A affects the fertility of male offspring. Life Sci 85:742-752.
    • (2009) Life Sci , vol.85 , pp. 742-752
    • Salian, S.1    Doshi, T.2    Vanage, G.3
  • 29
    • 41749092093 scopus 로고    scopus 로고
    • Testicular dysgenesis syndrome: Mechanistic insights and potential new downstream effects
    • Sharpe RM, Skakkebaek NE. 2008. Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertil Steril 89(suppl 2):33-38.
    • (2008) Fertil Steril , vol.89 , Issue.SUPPL. 2 , pp. 33-38
    • Sharpe, R.M.1    Skakkebaek, N.E.2
  • 30
    • 66349083181 scopus 로고    scopus 로고
    • Bisphenol A data in NHANES suggest longer than expected half-life, substantial nonfood exposure, or both
    • Stahlhut RW, Welshons WV, Swan SH. 2009. Bisphenol A data in NHANES suggest longer than expected half-life, substantial nonfood exposure, or both. Environ Health Perspect 117:784-789.
    • (2009) Environ Health Perspect , vol.117 , pp. 784-789
    • Stahlhut, R.W.1    Welshons, W.V.2    Swan, S.H.3
  • 32
    • 0031455688 scopus 로고    scopus 로고
    • Have sperm densities declined? A reanalysis of global trend data
    • Swan SH, Elkin EP, Fenster L. 1997. Have sperm densities declined? A reanalysis of global trend data. Environ Health Perspect 105:1228-1232.
    • (1997) Environ Health Perspect , vol.105 , pp. 1228-1232
    • Swan, S.H.1    Elkin, E.P.2    Fenster, L.3
  • 33
    • 0033595802 scopus 로고    scopus 로고
    • Exposure with the environmental estrogen bisphenol A disrupts the male reproductive tract in young mice
    • Takao T, Nanamiya W, Nagano I, Asaba K, Kawabata K, Hashimoto K. 1999. Exposure with the environmental estrogen bisphenol A disrupts the male reproductive tract in young mice. Life Sci 65:2351-2357.
    • (1999) Life Sci , vol.65 , pp. 2351-2357
    • Takao, T.1    Nanamiya, W.2    Nagano, I.3    Asaba, K.4    Kawabata, K.5    Hashimoto, K.6
  • 34
    • 0036082928 scopus 로고    scopus 로고
    • Serum bisphenol A concentrations showed gender differences, possibly linked to androgen levels
    • Takeuchi T, Tsutsumi O. 2002. Serum bisphenol A concentrations showed gender differences, possibly linked to androgen levels. Biochem Biophys Res Commun 291:76-78.
    • (2002) Biochem Biophys Res Commun , vol.291 , pp. 76-78
    • Takeuchi, T.1    Tsutsumi, O.2
  • 35
    • 0034993273 scopus 로고    scopus 로고
    • Bisphenol A inhibits testicular functions and increases luteinizing hormone secretion in adult male rats
    • Tohei A, Suda S, Taya K, Hashimoto T, Kogo H. 2001. Bisphenol A inhibits testicular functions and increases luteinizing hormone secretion in adult male rats. Exp Biol Med 226:216-221.
    • (2001) Exp Biol Med , vol.226 , pp. 216-221
    • Tohei, A.1    Suda, S.2    Taya, K.3    Hashimoto, T.4    Kogo, H.5
  • 37
    • 77955269249 scopus 로고    scopus 로고
    • Urinary, circulatingand tissue biomonitoring studies indicate widespread exposure to bisphenol A
    • doi: 10.1021/es9028292 [Online 24 March 2010]
    • Vandenberg LN, Chauhoud I, Heindel JJ, Padmanabhan V, Paumgartten FJ, Schoenfelder G. 2010. Urinary, circulatingand tissue biomonitoring studies indicate widespread exposure to bisphenol A. Environ Health Perspect 118:1055-1070; doi: 10.1021/es9028292 [Online 24 March 2010].
    • (2010) Environ Health Perspect , vol.118 , pp. 1055-1070
    • Vandenberg, L.N.1    Chauhoud, I.2    Heindel, J.J.3    Padmanabhan, V.4    Paumgartten, F.J.5    Schoenfelder, G.6
  • 38
    • 60549106214 scopus 로고    scopus 로고
    • Bisphenol-A and the great divide: A review of controversies in the field of endocrine disruption
    • Vandenberg LN, Maffini MV, Sonnenschein C, Rubin BS, Soto AM. 2009. Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption. Endocr Rev 30:75-95.
    • (2009) Endocr Rev , vol.30 , pp. 75-95
    • Vandenberg, L.N.1    Maffini, M.V.2    Sonnenschein, C.3    Rubin, B.S.4    Soto, A.M.5
  • 39
    • 0033305020 scopus 로고    scopus 로고
    • A critical evaluation of simple methods for the estimation of free testosterone in serum
    • Vermeulen A, Verdonck L, Kaufman JM. 1999. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 84:3666-3672.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3666-3672
    • Vermeulen, A.1    Verdonck, L.2    Kaufman, J.M.3
  • 40
    • 0031973887 scopus 로고    scopus 로고
    • A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior
    • vom Saal FS, Cooke PS, Buchanan DL, Palanza P, Thayer KA, Nagel SC, et al. 1998. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol Ind Health 14:239-260.
    • (1998) Toxicol Ind Health , vol.14 , pp. 239-260
    • vom Saal, F.S.1    Cooke, P.S.2    Buchanan, D.L.3    Palanza, P.4    Thayer, K.A.5    Nagel, S.C.6
  • 41
    • 34447121989 scopus 로고    scopus 로고
    • Clinical relevance of racial and ethnic differences in sex steroids [Editorial]
    • Wang C, Christenson P, Swerdloff R. 2007. Clinical relevance of racial and ethnic differences in sex steroids [Editorial]. J Clin Endocrinol Metab 92:2433-2435.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 2433-2435
    • Wang, C.1    Christenson, P.2    Swerdloff, R.3
  • 44
    • 23744507267 scopus 로고    scopus 로고
    • Automated on-line column-switching HPLC-MS/MS method with peak focusing for the determination of nine environmental phenols in urine
    • Ye X, Kuklenyik Z, Needham LL, Calafat AM. 2005. Automated on-line column-switching HPLC-MS/MS method with peak focusing for the determination of nine environmental phenols in urine. Anal Chem 77:5407-5413.
    • (2005) Anal Chem , vol.77 , pp. 5407-5413
    • Ye, X.1    Kuklenyik, Z.2    Needham, L.L.3    Calafat, A.M.4


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