Microwave-assisted synthesis and reversed-phase high-performance liquid chromatographic separation of diastereomers of (R,S)-baclofen using ten chiral derivatizing reagents designed from trichloro-s-triazine

Journal of Chromatography A

Volumn 1217, Issue 41, 2010, Pages 6382-6387

  Bhushan, Ravi ^a   Dixit, Shuchi ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

Author keywords

Baclofen; Dichloro s triazine; Indirect chiral separation; Microwave assisted synthesis; Monochloro s triazine; Reversed phase high performance liquid chromatography

Indexed keywords

BACLOFEN; INDIRECT CHIRAL SEPARATION; MICROWAVE-ASSISTED SYNTHESIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; S-TRIAZINES;

AMIDES; AMINO ACIDS; CHIRALITY; CHLORINE; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; METHANOL; ORGANIC ACIDS;

MICROWAVE IRRADIATION;

BACLOFEN; N (4 1 CARBAMOYL 2 METHYL PROPYLAMINO) 6 CHLORO [1,3,5] TRIAZINE 2 YL PHENYLALANINE; N (4 CHLORO 6 METHOXY [1,3,5] TRIAZINE 2 YL) ALANINAMIDE; N (4 CHLORO 6 METHOXY [1,3,5] TRIAZINE 2 YL) DEXTRO PHENYLGLYCINAMIDE; N (4 CHLORO 6 METHOXY [1,3,5] TRIAZINE 2 YL) LEUCINAMIDE; N (4 CHLORO 6 METHOXY [1,3,5] TRIAZINE 2 YL) METHIONINAMIDE; N (4 CHLORO 6 METHOXY [1,3,5] TRIAZINE 2 YL) VALINAMIDE; N (4,6 DICHLORO[1,3,5] TRIAZINE 2 YL) ALANINAMIDE; N (4,6 DICHLORO[1,3,5] TRIAZINE 2 YL) DEXTRO PHENYLGLYCINAMIDE; N (4,6 DICHLORO[1,3,5] TRIAZINE 2 YL) LEUCINAMIDE; N (4,6 DICHLORO[1,3,5] TRIAZINE 2 YL) VALINAMIDE; REAGENT; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CALIBRATION; CHIRALITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DERIVATIZATION; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; INTERMETHOD COMPARISON; MICROWAVE RADIATION; PH; PRIORITY JOURNAL; REACTION TIME; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; VALIDATION PROCESS;

AMINO ACIDS; BACLOFEN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; LINEAR MODELS; MICROWAVES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TRIAZINES;

EID: 77956783142     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.08.014     Document Type: Article

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