메뉴 건너뛰기




Volumn 14, Issue C, 1996, Pages 203-223

Physiology and Molecular Biology of P450c21 and P450c17

(1)  Chung, Bon chu a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77956757458     PISSN: 15692558     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1569-2558(08)60344-6     Document Type: Article
Times cited : (5)

References (77)
  • 1
    • 0026742799 scopus 로고
    • A novel 3′,5′-cyclic adenosine monophosphate-responsive sequence in the bovine CYP17 gene is a target of negative regulation by protein kinase C
    • Bakke M., and Lund J. A novel 3′,5′-cyclic adenosine monophosphate-responsive sequence in the bovine CYP17 gene is a target of negative regulation by protein kinase C. Mol. Endocrinol. 6 (1992) 1323-1331
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1323-1331
    • Bakke, M.1    Lund, J.2
  • 2
    • 0025994649 scopus 로고
    • Expression and enzymatic activity of recombinant cytochrome P450 17α-hydroxylase in Escherichia coli.
    • Barnes H.J., Arlotto M.P., and Waterman M.R. Expression and enzymatic activity of recombinant cytochrome P450 17α-hydroxylase in Escherichia coli. Proc. Natl. Acad. Sci USA 88 (1991) 5597-5601
    • (1991) Proc. Natl. Acad. Sci USA , vol.88 , pp. 5597-5601
    • Barnes, H.J.1    Arlotto, M.P.2    Waterman, M.R.3
  • 3
    • 0028076269 scopus 로고
    • Baculovirus expression of bovine cytochrome P450c 17 in Sf9 cells and comparison with expression in yeast, mammalian cells, and E. coli
    • Barnes H.J., Jenkins C.M., and Waterman M.R. Baculovirus expression of bovine cytochrome P450c 17 in Sf9 cells and comparison with expression in yeast, mammalian cells, and E. coli. Arch. Biochem. Biophys. 315 (1994) 419-494
    • (1994) Arch. Biochem. Biophys. , vol.315 , pp. 419-494
    • Barnes, H.J.1    Jenkins, C.M.2    Waterman, M.R.3
  • 5
    • 0026772930 scopus 로고
    • Angiotensin-II acts via the type 1 receptor to inhibit 17α-hydroxylase cytochrome P450 expression in ovine adrenocortical cells
    • Bird I.M., Magness R.R., Mason J.I., and Rainey W.E. Angiotensin-II acts via the type 1 receptor to inhibit 17α-hydroxylase cytochrome P450 expression in ovine adrenocortical cells. Endocrinology 130 (1992) 3113-3121
    • (1992) Endocrinology , vol.130 , pp. 3113-3121
    • Bird, I.M.1    Magness, R.R.2    Mason, J.I.3    Rainey, W.E.4
  • 6
    • 0025606854 scopus 로고
    • Tissuespecific, cyclic adenosine 3′,5′-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells
    • Brentano S.T., Picado-Leonard J., Mellon S.H., Moore C.C.D., and Miller W.L. Tissuespecific, cyclic adenosine 3′,5′-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells. Mol. Endocrinol. 4 (1990) 1972-1979
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1972-1979
    • Brentano, S.T.1    Picado-Leonard, J.2    Mellon, S.H.3    Moore, C.C.D.4    Miller, W.L.5
  • 7
    • 0027319656 scopus 로고
    • Abundant adrenal-specific transcription of the human P450c21A "Pseudogene"
    • Bristow J., Gitelman S.E., Tee M.K., and Miller W.L. Abundant adrenal-specific transcription of the human P450c21A "Pseudogene". J. Biol. Chem. 268 (1993) 12919-12924
    • (1993) J. Biol. Chem. , vol.268 , pp. 12919-12924
    • Bristow, J.1    Gitelman, S.E.2    Tee, M.K.3    Miller, W.L.4
  • 8
    • 0027231385 scopus 로고
    • Tenascin-X: A novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B
    • Bristow J., Tee M.K., Gitelman S.E., Mellon S.H., and Miller W.L. Tenascin-X: A novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B. J. Cell Biol. 122 (1993) 265-278
    • (1993) J. Cell Biol. , vol.122 , pp. 265-278
    • Bristow, J.1    Tee, M.K.2    Gitelman, S.E.3    Mellon, S.H.4    Miller, W.L.5
  • 9
    • 0027395742 scopus 로고
    • Oxygen availability as a regulatory factor of androgen synthesis by adrenocortical cells
    • Chabre O., Defaye G., and Chambaz E.M. Oxygen availability as a regulatory factor of androgen synthesis by adrenocortical cells. Endocrinology 132 (1993) 255-260
    • (1993) Endocrinology , vol.132 , pp. 255-260
    • Chabre, O.1    Defaye, G.2    Chambaz, E.M.3
  • 10
    • 0029101053 scopus 로고
    • Difference in transcriptional activity of two homologous CYP12A genes
    • Chang S.-F., and Chung B.-c. Difference in transcriptional activity of two homologous CYP12A genes. Mol. Endocrinol. 9 (1995) 1330-1336
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1330-1336
    • Chang, S.-F.1    Chung, B.-c.2
  • 11
    • 0025193526 scopus 로고
    • A Missense mutation at Ile172→Asn or Arg356→Trp cause steroid 21-hydroxylase deficiency
    • Chiou S.-H., Hu M.-C., and Chung B.-c. A Missense mutation at Ile172→Asn or Arg356→Trp cause steroid 21-hydroxylase deficiency. J. Biol. Chem. 265 (1990) 3549-3552
    • (1990) J. Biol. Chem. , vol.265 , pp. 3549-3552
    • Chiou, S.-H.1    Hu, M.-C.2    Chung, B.-c.3
  • 12
    • 0026062961 scopus 로고
    • The hydrophobic amino-terminal sequence of bovine 17α-hydroxylase is required for the expression of a functional hemoprotein in COS 1 cells
    • Clark B.J., and Waterman M.R. The hydrophobic amino-terminal sequence of bovine 17α-hydroxylase is required for the expression of a functional hemoprotein in COS 1 cells. J. Biol. Chem. 266 (1991) 5898-5904
    • (1991) J. Biol. Chem. , vol.266 , pp. 5898-5904
    • Clark, B.J.1    Waterman, M.R.2
  • 13
    • 0027523996 scopus 로고
    • Prenatal dexamethasone treatment in pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency: Effect on midgestational amniotic fluid steroid levels
    • Dorr H.G., and Sippell W.G. Prenatal dexamethasone treatment in pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency: Effect on midgestational amniotic fluid steroid levels. J. Clin. Endocrinol. Metab. 76 (1993) 117-120
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , pp. 117-120
    • Dorr, H.G.1    Sippell, W.G.2
  • 14
    • 0027059164 scopus 로고
    • Localization of the human CYP17 gene (cytochrome P450(17 alpha)) to 10q24.3 by fluorescence in situ hybridization and simultaneous chromosome banding
    • Fan Y.S., Sasi R., Lee C., Winter J.S., Waterman M.R., and Lin C.C. Localization of the human CYP17 gene (cytochrome P450(17 alpha)) to 10q24.3 by fluorescence in situ hybridization and simultaneous chromosome banding. Genomics 14 (1992) 1110-1111
    • (1992) Genomics , vol.14 , pp. 1110-1111
    • Fan, Y.S.1    Sasi, R.2    Lee, C.3    Winter, J.S.4    Waterman, M.R.5    Lin, C.C.6
  • 15
    • 0026638378 scopus 로고
    • Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus
    • Gitelman S.E., Bristow J., and Miller W.L. Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus. Mol. Cell. Biol. 12 (1992) 1237-1249
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1237-1249
    • Gitelman, S.E.1    Bristow, J.2    Miller, W.L.3
  • 16
    • 0027984276 scopus 로고
    • Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: Identification of a single protein that mediates both basal and cAMP-induced activities
    • Givens C.R., Zhang P., Bair S.R., and Mellon S.H. Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: Identification of a single protein that mediates both basal and cAMP-induced activities. DNA Cell Biol. 13 (1994) 1087-1098
    • (1994) DNA Cell Biol. , vol.13 , pp. 1087-1098
    • Givens, C.R.1    Zhang, P.2    Bair, S.R.3    Mellon, S.H.4
  • 18
    • 0023655719 scopus 로고
    • Testosterone inhibits cAMP-induced de novo synthesis of Leydig cell cytochrome P-45017α by an androgen receptor-mediated mechanism
    • Hales D.B., Sha L., and Payne A.H. Testosterone inhibits cAMP-induced de novo synthesis of Leydig cell cytochrome P-45017α by an androgen receptor-mediated mechanism. J. Biol. Chem. 262 (1987) 11200-11206
    • (1987) J. Biol. Chem. , vol.262 , pp. 11200-11206
    • Hales, D.B.1    Sha, L.2    Payne, A.H.3
  • 19
    • 0025330356 scopus 로고
    • Glucocorticoid and cyclic adenosine 3′5′-monophosphate-mediated induction of cholesterol side-chain cleavage cytochrome P450 (P450scc) in MA-10 tumor Leydig cells. Increases in mRNA are cycloheximide sensitive
    • Hales D.B., Sha L., and Payne A.H. Glucocorticoid and cyclic adenosine 3′5′-monophosphate-mediated induction of cholesterol side-chain cleavage cytochrome P450 (P450scc) in MA-10 tumor Leydig cells. Increases in mRNA are cycloheximide sensitive. Endocrinology 126 (1990) 2800-2808
    • (1990) Endocrinology , vol.126 , pp. 2800-2808
    • Hales, D.B.1    Sha, L.2    Payne, A.H.3
  • 20
    • 0026673224 scopus 로고
    • R339H and P453S: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions
    • Helmberg A., Tusie-Luna M.-T., Tabarelli M., Kofler R., and White P.C. R339H and P453S: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions. Mol. Endocrinol. 6 (1992) 1318-1322
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1318-1322
    • Helmberg, A.1    Tusie-Luna, M.-T.2    Tabarelli, M.3    Kofler, R.4    White, P.C.5
  • 21
    • 0024389562 scopus 로고
    • Regulation of steroid 17α-hydroxylase in adrenocortical cells in culture
    • Hornsby P.J. Regulation of steroid 17α-hydroxylase in adrenocortical cells in culture. Endocr. Res. 12 (1989) 159-182
    • (1989) Endocr. Res. , vol.12 , pp. 159-182
    • Hornsby, P.J.1
  • 22
    • 0027162561 scopus 로고
    • The N-terminal hydrophobic domain of P450c21 is required for membrane insertion and enzyme stability
    • Hsu L.-C., Hu M.-C., Cheng H.-C., Lu J.-C., and Chung B.-c. The N-terminal hydrophobic domain of P450c21 is required for membrane insertion and enzyme stability. J. Biol. Chem. 268 (1993) 14682-14686
    • (1993) J. Biol. Chem. , vol.268 , pp. 14682-14686
    • Hsu, L.-C.1    Hu, M.-C.2    Cheng, H.-C.3    Lu, J.-C.4    Chung, B.-c.5
  • 23
    • 0030020703 scopus 로고    scopus 로고
    • The common I172N Mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies of P450c21
    • Hsu L.-C., Hsu N.-C., Guzova J.A., Guzov V.M., Chang S.-F., and Chung B.-c. The common I172N Mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies of P450c21. J. Biol. Chem. 271 (1996) 3306-3310
    • (1996) J. Biol. Chem. , vol.271 , pp. 3306-3310
    • Hsu, L.-C.1    Hsu, N.-C.2    Guzova, J.A.3    Guzov, V.M.4    Chang, S.-F.5    Chung, B.-c.6
  • 24
    • 0025044007 scopus 로고
    • Expression of human 21-hydroxylase (P450c21) in bacterial and mammalian cells: A system to characterize normal and mutant enzymes
    • Hu M.-C., and Chung B.-c. Expression of human 21-hydroxylase (P450c21) in bacterial and mammalian cells: A system to characterize normal and mutant enzymes. Mol. Endocrinol. 4 (1990) 893-898
    • (1990) Mol. Endocrinol. , vol.4 , pp. 893-898
    • Hu, M.-C.1    Chung, B.-c.2
  • 25
    • 0025908208 scopus 로고
    • Interaction of phorbol ester and adrenocorticotropin in the regulation of steroidogenic P450 genes in human fetal and adult adrenal cell cultures
    • Ilvesmäki V., and Voutilainen R. Interaction of phorbol ester and adrenocorticotropin in the regulation of steroidogenic P450 genes in human fetal and adult adrenal cell cultures. Endocrinology 128 (1991) 1450-1458
    • (1991) Endocrinology , vol.128 , pp. 1450-1458
    • Ilvesmäki, V.1    Voutilainen, R.2
  • 26
    • 0027198401 scopus 로고
    • Expression and purification of functional human 17α-hydroxylase/l7,20-lyase (P450c 17) in Escherichia coli, use of this system for study of a novel form of combined 17α-hydroxylase/17,20-lyase deficiency
    • Imai T., Globerman H., Gertner J.M., Kagawa N., and Waterman M.R. Expression and purification of functional human 17α-hydroxylase/l7,20-lyase (P450c 17) in Escherichia coli, use of this system for study of a novel form of combined 17α-hydroxylase/17,20-lyase deficiency. J. Biol. Chem. 268 (1993) 19681-19689
    • (1993) J. Biol. Chem. , vol.268 , pp. 19681-19689
    • Imai, T.1    Globerman, H.2    Gertner, J.M.3    Kagawa, N.4    Waterman, M.R.5
  • 29
    • 0025780691 scopus 로고
    • Evidence that an adrenal-specific nuclear protein regulates the cAMP-responsiveness of the human CYP21B (P450c21) gene
    • Kagawa N., and Waterman M.R. Evidence that an adrenal-specific nuclear protein regulates the cAMP-responsiveness of the human CYP21B (P450c21) gene. J. Biol. Chem. 266 (1991) 11199-11204
    • (1991) J. Biol. Chem. , vol.266 , pp. 11199-11204
    • Kagawa, N.1    Waterman, M.R.2
  • 30
    • 0028986635 scopus 로고
    • The role of cytochrome b5 in the biosynthesis of androgens by human P450c17
    • Katagiri M., Kagawa N., and Waterman M.R. The role of cytochrome b5 in the biosynthesis of androgens by human P450c17. Arch Biochem. Biophys. 317 (1995) 343-347
    • (1995) Arch Biochem. Biophys. , vol.317 , pp. 343-347
    • Katagiri, M.1    Kagawa, N.2    Waterman, M.R.3
  • 33
    • 0021363227 scopus 로고
    • Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP
    • Kramer R.E., Rainey W.E., Funkenstein B., Dee A., Simpson E.R., and Waterman M.R. Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP. J. Biol. Chem. 259 (1984) 707-713
    • (1984) J. Biol. Chem. , vol.259 , pp. 707-713
    • Kramer, R.E.1    Rainey, W.E.2    Funkenstein, B.3    Dee, A.4    Simpson, E.R.5    Waterman, M.R.6
  • 34
    • 0025776916 scopus 로고
    • A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1
    • Kronbach T., Kemper B., and Johnson E.F. A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1. Biochemistry 30 (1991) 6097-6102
    • (1991) Biochemistry , vol.30 , pp. 6097-6102
    • Kronbach, T.1    Kemper, B.2    Johnson, E.F.3
  • 35
    • 0026665062 scopus 로고
    • Steroidogenic factor 1, a key regulator of steroidogenic enzyme expression, is the mouse homolog of'fushi tarazu-factor I
    • Lala D.S., Rice D.A., and Parker K.L. Steroidogenic factor 1, a key regulator of steroidogenic enzyme expression, is the mouse homolog of'fushi tarazu-factor I. Mol. Endocrinol. 6 (1992) 1249-1258
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1249-1258
    • Lala, D.S.1    Rice, D.A.2    Parker, K.L.3
  • 37
    • 0026702861 scopus 로고
    • In vivo effects of adrenocorticotropin on hamster adrenal steroidogenic enzymes
    • LeHoux J.-G., Mason J.I., and Ducharme L. In vivo effects of adrenocorticotropin on hamster adrenal steroidogenic enzymes. Endocrinology 131 (1992) 1874-1882
    • (1992) Endocrinology , vol.131 , pp. 1874-1882
    • LeHoux, J.-G.1    Mason, J.I.2    Ducharme, L.3
  • 40
    • 0027194106 scopus 로고
    • Differentiation of ovarian theca-interstitial cells in vitro: Regulation of 17α-hydroxylase messenger ribonucleic acid expression by leuteinizing hormone and insulin-like growth factor-I
    • Magoffin D.A., and Weitsman S.R. Differentiation of ovarian theca-interstitial cells in vitro: Regulation of 17α-hydroxylase messenger ribonucleic acid expression by leuteinizing hormone and insulin-like growth factor-I. Endocrinology 132 (1993) 1945-1951
    • (1993) Endocrinology , vol.132 , pp. 1945-1951
    • Magoffin, D.A.1    Weitsman, S.R.2
  • 42
    • 0024460383 scopus 로고
    • Extraadrenal steroid 21-hydroxylation is not mediated by P450c21
    • Mellon S.H., and Miller W.L. Extraadrenal steroid 21-hydroxylation is not mediated by P450c21. J. Clin. Invest. 84 (1989) 1497-1502
    • (1989) J. Clin. Invest. , vol.84 , pp. 1497-1502
    • Mellon, S.H.1    Miller, W.L.2
  • 43
    • 0023258576 scopus 로고
    • Molecular and clinical advances in congenital adrenal hyperplasia
    • Miller W.L., and Levine L.S. Molecular and clinical advances in congenital adrenal hyperplasia. J. Pediatric. 111 (1987) 1-17
    • (1987) J. Pediatric. , vol.111 , pp. 1-17
    • Miller, W.L.1    Levine, L.S.2
  • 44
    • 0024064517 scopus 로고
    • Molecular biology of steroid hormones synthesis
    • Miller W.L. Molecular biology of steroid hormones synthesis. Endocr. Rev. 9 (1988) 295-318
    • (1988) Endocr. Rev. , vol.9 , pp. 295-318
    • Miller, W.L.1
  • 45
    • 0024808985 scopus 로고
    • The molecular genetics of 21-hydroxylase deficiency
    • Miller W.L., and Morel Y. The molecular genetics of 21-hydroxylase deficiency. Annu. Rev. Genet. 23 (1989) 371-393
    • (1989) Annu. Rev. Genet. , vol.23 , pp. 371-393
    • Miller, W.L.1    Morel, Y.2
  • 46
    • 0026803454 scopus 로고
    • An element regulating adrenal-specific steroid 21-hydroxylase expression is located within the slp gene
    • Milstone D.S., Shaw S.K., Parker K.L., Szyf M., and Seidman J.G. An element regulating adrenal-specific steroid 21-hydroxylase expression is located within the slp gene. J. Biol. Chem. 267 (1992) 21924-21927
    • (1992) J. Biol. Chem. , vol.267 , pp. 21924-21927
    • Milstone, D.S.1    Shaw, S.K.2    Parker, K.L.3    Szyf, M.4    Seidman, J.G.5
  • 47
    • 0029940889 scopus 로고    scopus 로고
    • Variegated expression of a mouse steroid 21-hydroxylase/ß-galactosidase transgene suggests centripetal migration of adrenocorticol cells
    • in press
    • Morley S.C., Viard I., Chung B.-c., Ikeda Y., Parker K.L., and Mullins J.J. Variegated expression of a mouse steroid 21-hydroxylase/ß-galactosidase transgene suggests centripetal migration of adrenocorticol cells. Mol. Endocrinol. 10 (1996) in press
    • (1996) Mol. Endocrinol. , vol.10
    • Morley, S.C.1    Viard, I.2    Chung, B.-c.3    Ikeda, Y.4    Parker, K.L.5    Mullins, J.J.6
  • 49
    • 0023918714 scopus 로고
    • On the membrane topology of vertebrate cytochrome P-450 proteins
    • Nelson D.R., and Strobel H.W. On the membrane topology of vertebrate cytochrome P-450 proteins. J. Biol. Chem. 263 (1988) 6038-6050
    • (1988) J. Biol. Chem. , vol.263 , pp. 6038-6050
    • Nelson, D.R.1    Strobel, H.W.2
  • 50
    • 0025540520 scopus 로고
    • Prenatal diagnosis and treatment of adrenogenital syndrome (steroid 21-hydroxylase deficiency)
    • New M.I. Prenatal diagnosis and treatment of adrenogenital syndrome (steroid 21-hydroxylase deficiency). Dev. Pharm. Therap. 15 (1990) 200-210
    • (1990) Dev. Pharm. Therap. , vol.15 , pp. 200-210
    • New, M.I.1
  • 51
  • 53
    • 0027534442 scopus 로고
    • Transcriptional regulation of the adrenal steroidogenic enzymes
    • Parker K.L., and Schimmer B.P. Transcriptional regulation of the adrenal steroidogenic enzymes. Trends Endocrinol. Metab. 4 (1993) 46-50
    • (1993) Trends Endocrinol. Metab. , vol.4 , pp. 46-50
    • Parker, K.L.1    Schimmer, B.P.2
  • 54
    • 0025214553 scopus 로고
    • 17--20 lyase in Leydig cells
    • 17--20 lyase in Leydig cells. Biol. Reproduction 42 (1990) 399-404
    • (1990) Biol. Reproduction , vol.42 , pp. 399-404
    • Payne, A.H.1
  • 55
    • 0023550055 scopus 로고
    • Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): Similarity with the gene for P450c21
    • Picado-Leonard J., and Miller W.L. Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): Similarity with the gene for P450c21. DNA 6 (1987) 439-648
    • (1987) DNA , vol.6 , pp. 439-648
    • Picado-Leonard, J.1    Miller, W.L.2
  • 56
    • 0023761877 scopus 로고
    • Homologous sequences in steroidogenic enzymes, steroid receptors and a steroid binding protein suggest a consensus steroid-binding sequence
    • Picado-Leonard J., and Miller W.L. Homologous sequences in steroidogenic enzymes, steroid receptors and a steroid binding protein suggest a consensus steroid-binding sequence. Mol. Endocrinol. 2 (1988) 1145-1150
    • (1988) Mol. Endocrinol. , vol.2 , pp. 1145-1150
    • Picado-Leonard, J.1    Miller, W.L.2
  • 57
    • 0023645035 scopus 로고
    • High-resolution crystal structure of cytochrome P450cam
    • Poulos T.L., Finzel B.C., and Howar A.J. High-resolution crystal structure of cytochrome P450cam. J. Mol. Biol. 195 (1987) 687-700
    • (1987) J. Mol. Biol. , vol.195 , pp. 687-700
    • Poulos, T.L.1    Finzel, B.C.2    Howar, A.J.3
  • 58
    • 0023856655 scopus 로고
    • Regulation of aldosterone secretion
    • Quinn S.J., and Williams G.H. Regulation of aldosterone secretion. Ann. Rev. Physiol. 50 (1988) 409-426
    • (1988) Ann. Rev. Physiol. , vol.50 , pp. 409-426
    • Quinn, S.J.1    Williams, G.H.2
  • 64
    • 0025048753 scopus 로고
    • Expression of bovine cytochrome P450c21 and its fused enzymes with yeast NADPH-cytochrome P450 reductase in Saccharomyces cerevisiae.
    • Sakaki T., Shibata M., Yabusaki Y., Muarkami H., and Ohkawa H. Expression of bovine cytochrome P450c21 and its fused enzymes with yeast NADPH-cytochrome P450 reductase in Saccharomyces cerevisiae. DNA Cell Biol. 9 (1990) 603-614
    • (1990) DNA Cell Biol. , vol.9 , pp. 603-614
    • Sakaki, T.1    Shibata, M.2    Yabusaki, Y.3    Muarkami, H.4    Ohkawa, H.5
  • 65
    • 0023920360 scopus 로고
    • A segregation and linkage study of classical and nonclassical 21-hydroxylase deficiency
    • Sherman S.L., Aston C.E., Morton N.E., Speiser P.W., and New M.I. A segregation and linkage study of classical and nonclassical 21-hydroxylase deficiency. Am. J. Hum. Genet. 42 (1988) 830-838
    • (1988) Am. J. Hum. Genet. , vol.42 , pp. 830-838
    • Sherman, S.L.1    Aston, C.E.2    Morton, N.E.3    Speiser, P.W.4    New, M.I.5
  • 66
    • 0023244849 scopus 로고
    • Lethal deletion of the complement component C4 and steroid 21-hydroxylase genes in the mouse H-2 class III region, caused by meiotic recombination
    • Shiroishi T., Sagai T., Natsuume-Sakai S., and Moriwaki K. Lethal deletion of the complement component C4 and steroid 21-hydroxylase genes in the mouse H-2 class III region, caused by meiotic recombination. Proc. Natl. Acad. Sci. USA 84 (1987) 2819-2823
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2819-2823
    • Shiroishi, T.1    Sagai, T.2    Natsuume-Sakai, S.3    Moriwaki, K.4
  • 67
    • 0023868553 scopus 로고
    • Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH
    • Simpson E.R., and Waterman M.R. Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Ann. Rev. Physiol. 50 (1988) 427-440
    • (1988) Ann. Rev. Physiol. , vol.50 , pp. 427-440
    • Simpson, E.R.1    Waterman, M.R.2
  • 70
    • 0025696003 scopus 로고
    • Determination of functional effects of mutations in the steroid 21 -hydroxylase gene (CYP21) using recombinant vaccinia virus
    • Tusie-Luna M.-T., Traktman P., and White P.C. Determination of functional effects of mutations in the steroid 21 -hydroxylase gene (CYP21) using recombinant vaccinia virus. J. Biol. Chem. 265 (1990) 20916-20922
    • (1990) J. Biol. Chem. , vol.265 , pp. 20916-20922
    • Tusie-Luna, M.-T.1    Traktman, P.2    White, P.C.3
  • 71
    • 0027178430 scopus 로고
    • Levels of messenger ribonucleic acid for cytochrome P450 17α-hydroxylase and P450 aromatase in preovulatory bovine follicles decrease after the luteinizing hormone surge
    • Voss A.K., and Fortune J.E. Levels of messenger ribonucleic acid for cytochrome P450 17α-hydroxylase and P450 aromatase in preovulatory bovine follicles decrease after the luteinizing hormone surge. Endocrinology 132 (1993) 2239-2245
    • (1993) Endocrinology , vol.132 , pp. 2239-2245
    • Voss, A.K.1    Fortune, J.E.2
  • 72
    • 0026769613 scopus 로고
    • Steroid 21-hydroxylase deficiency: Three additional mutated alleles and establishment of phenotype-genotype relationships of common mutations
    • Wedell A., Ritzén E.M., Haglund-Stengler B., and Luthman H. Steroid 21-hydroxylase deficiency: Three additional mutated alleles and establishment of phenotype-genotype relationships of common mutations. Proc. Natl. Acad. Sci. USA 89 (1992) 7232-7236
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7232-7236
    • Wedell, A.1    Ritzén, E.M.2    Haglund-Stengler, B.3    Luthman, H.4
  • 73
    • 0027215606 scopus 로고
    • Steroid 21-hydroxylase (P450c21): A new allele and spread of mutations through the pseudogene
    • Wedell A., and Luthman H. Steroid 21-hydroxylase (P450c21): A new allele and spread of mutations through the pseudogene. Human Genetics. 91 (1993) 236-240
    • (1993) Human Genetics. , vol.91 , pp. 236-240
    • Wedell, A.1    Luthman, H.2
  • 74
    • 0025868941 scopus 로고
    • Expression and functional study of wild-type and mutant human cytochrome P450c21 in Saccharomyces cerevisiae.
    • Wu D.-A., Hu M.-C., and Chung B.-C. Expression and functional study of wild-type and mutant human cytochrome P450c21 in Saccharomyces cerevisiae. DNA Cell Biol. 10 (1991) 201-209
    • (1991) DNA Cell Biol. , vol.10 , pp. 201-209
    • Wu, D.-A.1    Hu, M.-C.2    Chung, B.-C.3
  • 75
    • 0025772912 scopus 로고
    • c21 (steroid 21-hydroxylase) at Cys 428, Val 281, and Ser 268 result in complete, partial, or no loss of enzymatic activity, respectively
    • c21 (steroid 21-hydroxylase) at Cys 428, Val 281, and Ser 268 result in complete, partial, or no loss of enzymatic activity, respectively. J. Clin. Invest. 88 (1991) 519-523
    • (1991) J. Clin. Invest. , vol.88 , pp. 519-523
    • Wu, D.-A.1    Chung, B.-C.2
  • 77
    • 0022847113 scopus 로고
    • Expression of bovine 17α-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS1) cells
    • Zuber M., Simpson E.R., and Waterman M.R. Expression of bovine 17α-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS1) cells. Science 234 (1986) 1258-1261
    • (1986) Science , vol.234 , pp. 1258-1261
    • Zuber, M.1    Simpson, E.R.2    Waterman, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.