N termini of apPDE4 isoforms are responsible for targeting the isoforms to different cellular membranes

Learning and Memory

Volumn 17, Issue 9, 2010, Pages 469-479

  Jang, Deok Jin ^a   Park, Soo Won ^a   Lee, Jin A ^b   Lee, Changhoon ^a   Chae, Yeon Su ^a   Park, Hyungju ^a   Kim, Min Jeong ^a   Choi, Sun Lim ^a   Lee, Nuribalhae ^a   Kim, Hyoung ^a   Kaang, Bong Kiun ^a  

^a Seoul National University   (South Korea)

^b Hannam University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; INOSITOL PHOSPHATE; ISOPROTEIN; PHOSPHODIESTERASE IV; SEROTONIN;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; APLYSIA; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; MEMBRANE DEPOLARIZATION; MOUSE; NERVE CELL PLASTICITY; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TARGETING; SENSORY NERVE CELL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; APLYSIA; CELL MEMBRANE; CELLS, CULTURED; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; CYSTEINE; GANGLIA, INVERTEBRATE; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOPRECIPITATION; MEMBRANE LIPIDS; MEMBRANE POTENTIALS; MUTATION; PRESYNAPTIC TERMINALS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; SENSORY RECEPTOR CELLS; SEROTONIN; SUBCELLULAR FRACTIONS; SYNAPTOPHYSIN; TRANSFECTION;

EID: 77956712201     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.1899410     Document Type: Article

References (40)

1. + current in the learning mutant rutabaga. Learn Mem 9: 368-375.
2. 2+-triggered membrane association with selectivity for interaction with phosphatidic acid. J Biol Chem 277: 28298-28309.
3. Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E. 1998. Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc Natl Acad Sci 95: 15020-15025.
4. Barbas D, Zappulla JP, Angers S, Bouvier M, Mohamed HA, Byrne JH, Castellucci VF, DesGroseillers L. 2006. An aplysia dopamine1-like receptor: Molecular and functional characterization. J Neurochem 96: 414-427.
5. Bauer AC, Schwabe U. 1980. An improved assay of cyclic 3′,5′-nucleotide phosphodiesterases with QAE-Sephadex columns. Naunyn Schmiedebergs Arch Pharmacol 311: 193-198.
6. Berke B, Wu CF. 2002. Regional calcium regulation within cultured Drosophila neurons: Effects of altered cAMP metabolismby the learning mutations dunce and rutabaga. J Neurosci 22: 4437-4447.
7. Blokland A, Schreiber R, Prickaerts J. 2006. Improving memory: A role for phosphodiesterases. Curr Pharm Des 12: 2511-2523.
8. Bolger GB, McCahill A, Huston E, Cheung YF, McSorley T, Baillie GS, Houslay MD. 2003. The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with β-arrestins. J Biol Chem 278: 49230-49238.
9. Bourtchouladze R, Lidge R, Catapano R, Stanley J, Gossweiler S, Romashko D, Scott R, Tully T. 2003. A mouse model of Rubinstein-Taybi syndrome: Defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4. Proc Natl Acad Sci 100: 10518-10522.
10. Byers D, Davis RL, Kiger JA Jr, 1981. Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster. Nature 289: 79-81.
11. Byrne JH, Kandel ER. 1996. Presynaptic facilitation revisited: State and time dependence. J Neurosci 16: 425-435.
12. Chang DJ, Li XC, Lee YS, Kim HK, Kim US, Cho NJ, Lo X, Weiss KR, Kandel ER, Kaang BK. 2000. Activation of a heterologously expressed octopamine receptor coupled only to adenylyl cyclase produces all the features of presynaptic facilitation in aplysia sensory neurons. Proc Natl Acad Sci 97: 1829-1834.
13. Davis RL. 1996. Physiology and biochemistry of Drosophila learning mutants. Physiol Rev 76: 299-317.
14. Delacour D, Gouyer V, Zanetta JP, Drobecq H, Leteurtre E, Grard G, Moreau-Hannedouche O, Maes E, Pons A, Andre S, et al. 2005. Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells. J Cell Biol 169: 491-501.
15. Di Paolo G, De Camilli P. 2006. Phosphoinositides in cell regulation and membrane dynamics. Nature 443: 651-657.
16. Dodge KL, Khouangsathiene S, Kapiloff MS, Mouton R, Hill EV, Houslay MD, Langeberg LK, Scott JD. 2001. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J 20: 1921-1930.
17. Dudai Y, Jan YN, Byers D, Quinn WG, Benzer S. 1976. dunce, a mutant of Drosophila deficient in learning. Proc Natl Acad Sci 73: 1684-1688.
18. El-Husseini AE, Bredt DS. 2002. Protein palmitoylation: A regulator of neuronal development and function. Nat Rev Neurosci 3: 791-802.
19. Grange M, Sette C, Cuomo M, Conti M, Lagarde M, Prigent AF, Nemoz G. 2000. The cAMP-specific phosphodiesterase PDE4D3 is regulated by phosphatidic acid binding. Consequences for cAMP signaling pathway and characterization of a phosphatidic acid binding site. J Biol Chem 275: 33379-33387.
20. Gruber A, Zingales B. 1995. Alternative method to remove antibacterial antibodies from antisera used for screening of expression libraries. Biotechniques 19: 28, 30.
21. Hanada K, Kumagai K, Yasuda S, Miura Y, Kawano M, Fukasawa M, Nishijima M. 2003. Molecular machinery for non-vesicular trafficking of ceramide. Nature 426: 803-809.
22. Houslay MD, Adams DR. 2003. PDE4 cAMP phosphodiesterases: Modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization. Biochem J 370: 1-18.
23. Houslay MD, Baillie GS, Maurice DH. 2007. cAMP-specific phosphodiesterase-4 enzymes in the cardiovascular system: A molecular toolbox for generating compartmentalized cAMP signaling. Circ Res 100: 950-966.
24. Huang YY, Nguyen PV, Abel T, Kandel ER. 1996. Long-lasting forms of synaptic potentiation in the mammalian hippocampus. Learn Mem 3: 74-85.
25. 2+. J Cell Sci 119: 3799-3810.
26. Kanaani J, El-Husseini AE, Aguilera-Moreno A, Diacovo JM, Bredt DS, Baekkeskov S. 2002. A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65. J Cell Biol 158: 1229-1238.
27. Kanaani J, Patterson G, Schaufele F, Lippincott-Schwartz J, Baekkeskov S. 2008. A palmitoylation cycle dynamically regulates partitioning of the GABA-synthesizing enzyme GAD65 between ER-Golgi and post-Golgi membranes. J Cell Sci 121: 437-449.
28. Lee JA, Kim HK, Kim KH, Han JH, Lee YS, Lim CS, Chang DJ, Kubo T, Kaang BK. 2001. Overexpression of and RNA interference with the CCAAT enhancer-binding protein on long-term facilitation of Aplysia sensory to motor synapses. Learn Mem 8: 220-226.
29. Lee YS, Choi SL, Lee SH, Kim H, Park H, Lee N, Chae YS, Jang DJ, Kandel ER, Kaang BK. 2009. Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia. Proc Natl Acad Sci 106: 14634-14639.
30. Lemmon MA. 2008. Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 9: 99-111.
31. McCahill AC, Huston E, Li X, Houslay MD. 2008. PDE4 associates with different scaffolding proteins: Modulating interactions as treatment for certain diseases. Handb Exp Pharmacol 186: 125-166.
32. Millar JK, Pickard BS, Mackie S, James R, Christie S, Buchanan SR, Malloy MP, Chubb JE, Huston E, Baillie GS, et al. 2005. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310: 1187-1191.
33. Montarolo PG, Goelet P, Castellucci VF, Morgan J, Kandel ER, Schacher S. 1986. A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. Science 234: 1249-1254.
34. Park H, Lee JA, Lee C, Kim MJ, Chang DJ, Kim H, Lee SH, Lee YS, Kaang BK. 2005. An Aplysia type 4 phosphodiesterase homolog localizes at the presynaptic terminals of Aplysia neuron and regulates synaptic facilitation. J Neurosci 25: 9037-9045.
35. Shakur Y, Pryde JG, Houslay MD. 1993. Engineered deletion of the unique N-terminal domain of the cyclic AMP-specific phosphodiesterase RD1 prevents plasma membrane association and the attainment of enhanced thermostability without altering its sensitivity to inhibition by rolipram. Biochem J 292: 677-686.
36. Soderling SH, Beavo JA. 2000. Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions. Curr Opin Cell Biol 12: 174-179.
37. Spina D. 2008. PDE4 inhibitors: Current status. Br J Pharmacol 155: 308-315.
38. Tasken KA, Collas P, Kemmner WA, Witczak O, Conti M, Tasken K. 2001. Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area. J Biol Chem 276: 21999-22002.
39. Yarwood SJ, Steele MR, Scotland G, Houslay MD, Bolger GB. 1999. The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J Biol Chem 274: 14909-14917.
40. Zhong Y, Wu CF. 1991. Altered synaptic plasticity in Drosophila memory mutants with a defective cyclic AMP cascade. Science 251: 198-201.