Oleanane-type triterpene glucuronides from the roots of Glycyrrhiza uralensis Fischer

Planta Medica

Volumn 76, Issue 13, 2010, Pages 1457-1463

  Zheng, Yun Feng ^a,b   Qi, Lian Wen ^a   Cui, Xiao Bing ^b   Peng, Guo Ping ^b   Peng, Yong Bo ^a   Ren, Mei Ting ^a   Cheng, Xiao Lan ^a   Li, Ping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

cytotoxic activities; Glycyrrhiza; Glycyrrhiza uralensis Fischer; Leguminosae; triterpene glucuronides; uralsaponins CF

Indexed keywords

22BETA ACETOXY GLYCYRRHIZIN; 3 O [BETA DEXTRO GLUCURONOPYRANOSYL (1-2) BETA DEXTRO GLUCURONOPYRANOSYL] 24 HYDROXYGLABROLIDE; ANTINEOPLASTIC AGENT; FLUOROURACIL; GLYCYRRHIZIC ACID; LICORICE SAPONIN A3; LICORICE SAPONIN E2; LICORICE SAPONIN G2; UNCLASSIFIED DRUG; URALSAPONIN C; URALSAPONIN D; URALSAPONIN E; URALSAPONIN F;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN MCF 7; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; GLYCYRRHIZA URALENSIS; HELA CELL; HUMAN; HUMAN CELL; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GLYCYRRHIZA; GLYCYRRHIZIC ACID; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; NEOPLASMS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; SAPONINS; STRUCTURE-ACTIVITY RELATIONSHIP;

FABACEAE; GLYCYRRHIZA; GLYCYRRHIZA URALENSIS;

EID: 77956693119     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1240907     Document Type: Article

References (14)

1. Kitagawa I, Hori K, Taniyama T, Zhou J L., Yoshikawa M. On the constituents of the roots of Glycyrrhiza uralensis Fischer from northeastern China. (1). Licorice-saponins A3, B2, and C2. Chem Pharm Bull 1993 41 43-49
2. Ling B, Yang A F., Huang F L., Hu B Z. Research advances on chemical constituents and pharmacological activities in Glycyrrhiza. J Northeast Agric Univ 2006 37 115-119
3. Asl M N., Hosseinzadeh H. Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytother Res 2008 22 709-724
4. Shiota G, Harada K, Ishida M, Tomie Y, Okubo M, Katayama S, Ito H, Kawasaki H. Inhibition of hepatocellular carcinoma by glycyrrhizin in diethylnitrosamine-treated mice. Carcinogenesis 1999 20 59-63
5. Shin Y W., Bae E A., Lee B, Lee S H., Kim J A., Kim Y S., Kim D H. In vitro and in vivo antiallergic effects of Glycyrrhiza glabra and its components. Planta Med 2007 73 257-261
6. Wolkerstorfer A, Kurz H, Bachhofner N, Szolar O H. Glycyrrhizin inhibits influenza A virus uptake into the cell. Antiviral Res 2009 83 171-178
7. Zhang R Y., Zhang J H., Wang M T. Studies on the saponins from the roots of Glycyrrhiza uralensis Fischer. Acta Pharm Sin 1986 21 510-515
8. Wang Y, Che C M., Chiu J F., He Q Y. Dioscin (saponin)-induced generation of reactive oxygen species through mitochondria dysfunction: a proteomic-based study. J Proteome Res 2007 6 4703-4710
9. Huang Q, Qiao X B., Xu X J. Potential synergism and inhibitors to multiple target enzymes of Xuefu Zhuyu decoction in cardiac disease therapeutics: a computational approach. Bioorg Med Chem Lett 2007 17 1779-1783
10. Kitagawa I, Hori K, Sakagami M, Zhou J L., Yoshikawa M. On the constituents of the roots of Glycyrrhiza uralensis Fischer from northeastern China (1). Licorice-saponins D3, E2, F3, G2, H2, J2, and C2. Chem Pharm Bull 1993 41 1337-1345 (Pubitemid 23285529)
11. Jinwei L, Nakajima J, Kimura N, Saito K, Seo S. Oleanane-type triterpene glycosides from Glycyrrhiza uralensis. Nat Prod Commun 2007 2 243-248
12. Li W, Sha Y, Chen L X., Qiu F, Wu L J. NMR data assignments of two 18-epimers of diammonium glycyrrhizinate. J Shenyang Pharm Univ 2005 22 273-278
13. Antonov A S., Avilov S A., Kalinovsky A I., Anastyuk S D., Dmitrenok P S., Kalinin V I., Taboada S, Bosh A, Avila C, Stonik V A. Triterpene glycosides from antarctic sea cucumbers. 2. Structure of achlioniceosides A1, A2, and A3 from the sea cucumber Achlionice violaecuspidata (Rhipidothuria racowitzai). J Nat Prod 2009 72 33-38
14. Zhu X M., Di Y T., Peng S L., Wang M K., Ding L S. Chemical constituents from root of Glycyrrhiza uralensis. Chin Tradit Herb Drugs 2003 34 198-201