Internalization of the opioid growth factor, [Met5]-enkephalin, is dependent on clathrin-mediated endocytosis for downregulation of cell proliferation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 299, Issue 3, 2010, Pages

  Cheng, Fan ^a   McLaughlin, Patricia J ^a   Banks, William A ^b   Zagon, Ian S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Active transport; DNA synthase; Human mesenchymal stem cells; Nucleocytoplasmic transport; siRNA

Indexed keywords

CLATHRIN; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; METENKEPHALIN; NALTREXONE; OPIOID GROWTH FACTOR; OPIOID GROWTH FACTOR RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BETA CYCLODEXTRIN DERIVATIVE; CADAVERINE; CULTURE MEDIUM; DANSYLCADAVERINE; METHYL-BETA-CYCLODEXTRIN; RHODAMINE;

ANIMAL CELL; ARTICLE; CELL LABELING; CELL NUCLEUS; CELL PROLIFERATION; CELL TRANSPORT; CONTROLLED STUDY; CYTOPLASM; DNA SYNTHESIS; DOWN REGULATION; ENDOCYTOSIS; ENDOSOME; GOLGI COMPLEX; HOMEOSTASIS; HUMAN; HUMAN CELL; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TEMPERATURE DEPENDENCE; UPREGULATION; WOUND HEALING; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; CULTURE MEDIUM; DRUG EFFECTS; FEMALE; MESENCHYMAL STROMA CELL; METABOLISM; OVARY TUMOR; PHYSIOLOGY; STAINING; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BETA-CYCLODEXTRINS; BIOLOGICAL TRANSPORT; CADAVERINE; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; CLATHRIN; COS CELLS; CULTURE MEDIA, SERUM-FREE; DOWN-REGULATION; ENDOCYTOSIS; ENDOSOMES; ENKEPHALIN, METHIONINE; FEMALE; GOLGI APPARATUS; HUMANS; MESENCHYMAL STEM CELLS; OVARIAN NEOPLASMS; RHODAMINES; RNA, SMALL INTERFERING; STAINING AND LABELING; MESENCHYMAL STROMAL CELLS;

EID: 77956670895     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00318.2010     Document Type: Article

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