The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcγRIIIa-48L/R/H polymorphism

International Journal of Molecular Medicine

Volumn 26, Issue 3, 2010, Pages 435-442

  Lenart, Marzena ^a   Trzyna, Elzbieta ^a   Rutkowska, Magdalena ^a   Bukowska Strakova, Karolina ^a   Szaflarska, Anna ^a   Pituch Noworolska, Anna ^a   Szczepanik, Antoni ^b   Zembala, Marek ^a   Siedlar, Maciej ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

B73.1 Leu11c monoclonal antibody; CD16a; Fc receptor for IgG type III polymorphism

Indexed keywords

CD16 ANTIGEN; EPITOPE; FC RECEPTOR; MONOCLONAL ANTIBODY; FCGR3B PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN;

ADOLESCENT; ADULT; ANTIGEN BINDING; ARTICLE; CHILD; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DNA POLYMORPHISM; FEMALE; GENE SEQUENCE; GENETIC ANALYSIS; GENOTYPE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; SEQUENCE ANALYSIS; VIRUS INFECTION; DNA SEQUENCE; GENETIC POLYMORPHISM; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD;

ADOLESCENT; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; EPITOPES; FEMALE; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; MALE; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; RECEPTORS, IGG; SEQUENCE ANALYSIS, DNA; GPI-LINKED PROTEINS;

EID: 77956660193     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm-00000483     Document Type: Article

References (30)

1. Ravetch JV and Perussia B: Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions. J Exp Med 170: 481-497, 1989.
2. Passlick B, Flieger D and Ziegler-Heitbrock HWL: Identification and characterization of a novel monocyte subpopulation in human peripheral blood. Blood 74: 2527-2534, 1989. (Pubitemid 19286475)
3. Van de Winkel JG and Capel PJ: Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today 14: 215-221, 1993.
4. Robertson MJ and Ritz J: Biology and clinical relevance of human natural killer cells. Blood 76: 2421-2438, 1990.
5. Van de Winkel JG and Anderson CL: Biology of human immunoglobulin G Fc receptors. J Leukoc Biol 49: 511-524, 1991.
6. Cooper MA, Fehniger TA, Turner SC, et al: Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset. Blood 97: 3146-3151, 2001.
7. Tamm A and Schmidt RE: The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding. J Immunol 157: 1576-1581, 1996. (Pubitemid 126449096)
8. De Vries E, Koene HR, Vossen JM, et al: Identification of an unusual Fcγ receptor IIIa (CD16) on natural killer cells in a patient with recurrent infections. Blood 88: 3022-3027, 1996.
9. Peltz GA, Grundy HO, Lebo RV, Yssel H, Barsh GS and Moore KW: Human FcγRIII: Cloning, expression and identification on of the chromosomal locus of two Fc receptors for IgG. Proc Natl Acad Sci USA 86: 1013-1017, 1989.
10. De Haas M, Koene HR, Kleijer M, et al: A triallelic Fcγ receptor type IIIA polymorphism influences the binding of human IgG by NK cell Fc-gamma-RIIIA. J Immunol 156: 2948-2955, 1996.
11. Hibbs ML, Tolvanen M and Carpén O: Membrane-proximal Ig-like domain of FcγRIII (CD16) contains residues critical for ligand binding. J Immunol 152: 4466-4474, 1994. (Pubitemid 24134404)
12. Koene HR, Kleijer M, Algra J, Roos D, von dem Borne AE and de Haas M: Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype. Blood 90: 1109-1114, 1997.
13. Wu J, Edberg JC, Redecha PB, et al: A novel polymorphism of FcγRIIIA (CD16) alters receptor function and predisposes to autoimmune disease. J Clin Invest 100: 1059-1070, 1997.
14. Koene HR, Kleijer M, Swaak AJ, et al: The Fc-gamma-RIIIA-158F allele is a risk factor for systemic lupus erythematosus. Arthritis Rheum 41: 1813-1818, 1998.
15. Seligman VA, Suarez C, Lum R, et al: The Fcgamma receptor IIIA-158F allele is a major risk factor for the development of lupus nephritis among Caucasians but not non-Caucasians. Arthritis Rheum 44: 618-625, 2001.
16. Morgan AW, Keyte VH, Babbage SJ, et al: FcγRIIIA-158V and rheumatoid arthritis: a confirmation study. Rheumatology 42: 528-533, 2003.
17. Kastbom A, Ahmadi A, Söderkvist P and Skogh T: The 158V polymorphism of Fc gamma receptor type IIIA in early rheumatoid arthritis: increased susceptibility and severity in male patients (the Swedish TIRA project). Rheumatology 44: 1294-1298, 2005. (Pubitemid 41487964)
18. Cartron G, Dacheux L, Salles G, et al: Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor Fc-gamma-RIIIa gene. Blood 99: 754-758, 2002.
19. Dall'Ozzo S, Tartas S, Paintaud G, et al: Rituximab-dependent cytotoxicity by natural killer cells: influence of FCGR3A polymorphism on the concentration-effect relationship. Cancer Res 64: 4664-4669, 2004.
20. Treon SP, Hansen M, Branagan AR, et al: Polymorphisms in FcγRIIIA (CD16) receptor expression are associated with clinical response to rituximab in Waldenström's macroglobulinemia. J Clin Oncol 23: 474-481, 2005.
21. Musolino A, Naldi N, Bortesi B, et al: Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol 26: 1789-1796, 2008.
22. Jawahar S, Moody C, Chan M, Finberg R, Geha R and Chatila T: Natural killer (NK) cell deficiency associated with an epitope-deficient Fc receptor type IIIA (CD16-II). Clin Exp Immunol 103: 408-413, 1996.
23. Forbes LR, Paessler M and Orange JS: CD16 deficiency discovered in a cohort of patients with severe herpesviral infections using a new diagnostic test. J Allergy Clin Immunol 123: S67(abs. 245), 2009.
24. Kankirawatana S, Dai Y and Atkinson P: A six year old girl with reccurent varicella infections associated with a mutation in CD16 (FCGR3A, FcγRIIIa). World Allergy Organiz J 134: abst. 420, 2007.
25. Conley ME, Nortarangelo LD and Etzioni A: Diagnostic criteria for primary immunodeficiencies. Clin Immunol 93: 190-197, 1999.
26. Walker A, Kemp A, Hill D and Shelton M: Features of transient hypogammaglobulinemia in infants screened for immunological abnormalities. Arch Dis Child 70: 183-186, 1994. (Pubitemid 24136402)
27. Strayer DR, Carter WA and Brodsky I: Familial occurrence of breast cancer is associated with reduced natural killer cytotoxicity. Breast Cancer Res Treat 7: 187-192, 1986.
28. Bonilla FA, Bernstein IL, Khan DA, et al: Practice parameter for the diagnosis and management of primary immunodeficiency. Ann Allergy Asthma Immunol 94: 1-63, 2005.
29. Anderson CL, Looney RJ, Culp DJ, et al: Human alveolar and peritoneal macrophages bear three distinct classes of Fc receptors for IgG. J Immunol 145: 196-201, 1990.
30. Weisenseel P, Martin S, Partscht K, Messer G and Prinz JC: Relevance of the low-affinity type of the Fcgamma-receptor IIIa-polymorphism in bullous pemphigoid. Arch Dermatol Res 299: 163-164, 2007.