Immortalized mouse brain endothelial cell line Bend. 3 Displays the comparative barrier characteristics as the primary brain microvascular endothelial cells

Chinese Journal of Contemporary Pediatrics

Volumn 12, Issue 6, 2010, Pages 474-478

  He, Fang ^a   Yin, Fei ^a   Peng, Jing ^a   Li, Kong Zhao ^a   Wu, Li Wen ^a   Deng, Xiao Lu ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Barrier; Brain microvascular endothelial cell line; Mice; Tight junction

Indexed keywords

F ACTIN; HORSERADISH PEROXIDASE; ACTIN; MEMBRANE PROTEIN; PHOSPHOPROTEIN; PROTEIN ZO1; ZONULA OCCLUDENS-1 PROTEIN;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL MEMBRANE; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; FLUORESCENCE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TIGHT JUNCTION; WESTERN BLOTTING; ANIMAL; BLOOD BRAIN BARRIER; CELL LINE; IMPEDANCE; METABOLISM;

ACTINS; ANIMALS; BLOOD-BRAIN BARRIER; CELL LINE; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; HORSERADISH PEROXIDASE; MEMBRANE PROTEINS; MICE; PHOSPHOPROTEINS;

EID: 77956639279     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Rubin L, Staddonthe MJ. Cell biology of the blood-brain barrier[J]. Annu Rev Neurosci, 1999,22(1):11-28.
2. Wolburg H, Lippoldt A. Tight junctions of the blood-brain barrier: development, composition and regulation[J]. Vascular Pharmacol, 2002,38(6):323-337.
3. Legros H, Launay S, Roussel BD, Marcou-Labarre A, Calbo S, Laudenbach V, et al. Newborn- and adult- derived brain microvascular endothelial cells show age-related differences in phenotype and glutamate-evoked protease release[J]. J Cereb Blood Flow Metab, 2009,29(6):1146-1158.
4. Roux F, Couraud PO. Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport function[J]. Cell Mol Neurobiol, 2005,25(1):41-58.
5. Brown RC, Morris AP, O'Neil RG. Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells[J]. Brain Res, 2007,1130(1):17-30.
6. Yamamoto M, Ramirez SH, Sato S, Kiyota T, Cerny RL, Ikezu T. Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells[J]. Am J Pathol, 2008,172(2):521-533.
7. Cucullo L, Couraud PO, Weksler B, Romero IA, Hossain M, Janigro D. Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies[J]. J Cereb Blood Flow Metab, 2008,28(2):312-328.
8. Schiera G, Sala S, Gallo A, Raffa MP, Pitarresi GL, Di Liegro I, et al. Permeability properties of a three-cell type in vitro model of blood-brain barrier[J]. J Cell Mol Med, 2005,9(2):373-379.
9. Lossinsky AS, Shivers RR. Structural pathways for macromolecular and cellular transport across the blood-brain barrier during inflammatory conditions[J]. Histol Histopathol, 2004,19(2):535-564.
10. Olga CC, Nora TC, Gail F, Ronan PM, Yvonne AB, Paul AC, et al. Influence of basolateral condition on the regulation of brain microvascular endothelial tight junction properties and barrier function[J]. Brain Res, 2008,1193:84-92.
11. Dohgu S, Banks WA. Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by the p38 mitogen-activated protein kinase pathway[J]. Exp Neurol, 2008,210(2):740-749.