Calcification of cartilage formed in vitro on calcium polyphosphate bone substitutes is regulated by inorganic polyphosphate

Acta Biomaterialia

Volumn 6, Issue 8, 2010, Pages 3302-3309

  St Pierre, Jean Philippe ^a   Pilliar, Robert M ^a,b,c   Grynpas, Marc D ^a,c   Kandel, Rita A ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Articular cartilage; Cartilage tissue engineering; Chondrocytes; Inorganic polyphosphate; Mineralization

Indexed keywords

BIOMINERALIZATION; BODY FLUIDS; BONE; CALCIUM COMPOUNDS; DEGRADATION; TISSUE ENGINEERING;

ARTICULAR CARTILAGES; BONE SUBSTITUTES; CALCIUM POLYPHOSPHATE; CARTILAGE TISSUE ENGINEERING; CHONDROCYTES; CLINICAL APPLICATION; IN-VITRO; INORGANIC POLYPHOSPHATE; MINERALISATION; POLYPHOSPHATES;

CARTILAGE;

CALCIUM POLYPHOSPHATE; POLYPHOSPHATE; UNCLASSIFIED DRUG; CALCIUM; PHOSPHATE; PHOSPHORIC ACID; POLYMER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BONE MINERALIZATION; BONE PROSTHESIS; BONE REGENERATION; CALCIFICATION; CONCENTRATION (PARAMETERS); DEGRADATION KINETICS; DRY WEIGHT; ENZYME ACTIVITY; HYDROLYSIS; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; TISSUE ENGINEERING; ANIMAL; CARTILAGE; CARTILAGE CELL; CATTLE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALS; BONE SUBSTITUTES; CALCIFICATION, PHYSIOLOGIC; CALCIUM; CARTILAGE; CATTLE; CHONDROCYTES; PHOSPHATES; PHOSPHORIC ACIDS; POLYMERS;

EID: 77956622910     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.02.033     Document Type: Article

References (51)

1. Hunziker EB. Articular cartilage repair: are the intrinsic biological constraints undermining this process insuperable? Osteoarthritis Cartilage 1999;7(1):15-28.
2. Kinner B, Capito RM, Spector M. Regeneration of articular cartilage. Adv Biochem Eng Biotechnol 2005;94:91-123.
3. Hunziker EB. Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthritis Cartilage 2002;10(6):432-63.
4. Simon TM, Jackson DW. Articular cartilage: injury pathways and treatment options. Sports Med Arthrosc 2006;14(3):146-54.
5. Mikos AG, Herring SW, Ochareon P, Elisseeff J, Lu HH, Kandel R, et al. Engineering complex tissues. Tissue Eng 2006;12(12):3307-39.
6. Ahsan T, Sah RL. Biomechanics of integrative cartilage repair. Osteoarthritis Cartilage 1999;7(1):29-40.
7. Keeney M, Pandit A. The osteochondral junction and its repair via bi-phasic tissue engineering scaffolds. Tissue Eng B Rev 2009;15(1):55-73.
8. Gao J, Dennis JE, Solchaga LA, Goldberg VM, Caplan AI. Repair of osteochondral defect with tissue-engineered two-phase composite material of injectable calcium phosphate and hyaluronan sponge. Tissue Eng 2002;8(5):827-37.
9. Jiang CC, Chiang H, Liao CJ, Lin YJ, Kuo TF, Shieh CS, et al. Repair of porcine articular cartilage defect with a biphasic osteochondral composite. J Orthop Res 2007;25(10):1277-90.
10. Niederauer GG, Slivka MA, Leatherbury NC, Korvick DL, Harroff HH, Ehler WC, et al. Evaluation of multiphase implants for repair of focal osteochondral defects in goats. Biomaterials 2000;21(24):2561-74.
11. Tanaka T, Komaki H, Chazono M, Fujii K. Use of a biphasic graft constructed with chondrocytes overlying a beta-tricalcium phosphate block in the treatment of rabbit osteochondral defects. Tissue Eng 2005;11(1-2):331-9.
12. Van Susante JL, Buma P, Homminga GN, van den Berg WB, Veth RP. Chondrocyte-seeded hydroxyapatite for repair of large articular cartilage defects. A pilot study in the goat. Biomaterials 1998;19(24):2367-74.
13. Shao XX, Hutmacher DW, Ho ST, Goh JC, Lee EH. Evaluation of a hybrid scaffold/cell construct in repair of high-load-bearing osteochondral defects in rabbits. Biomaterials 2006;27(7):1071-80.
14. Kandel RA, Grynpas M, Pilliar R, Lee J, Wang J, Waldman S, et al. Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model. Biomaterials 2006;27(22):4120-31.
15. Schaefer D, Martin I, Jundt G, Seidel J, Heberer M, Grodzinsky A, et al. Tissueengineered composites for the repair of large osteochondral defects. Arthritis Rheum 2002;46(9):2524-34.
16. Chen G, Sato T, Tanaka J, Tateishi T. Preparation of a biphasic scaffold for osteochondral tissue engineering. Mater Sci Eng C 2006;26(1):118-23. (Pubitemid 41817134)
17. Petersen JP, Ueblacker P, Goepfert C, Adamietz P, Baumbach K, Stork A, et al. Long term results after implantation of tissue engineered cartilage for the treatment of osteochondral lesions in a minipig model. J Mater Sci Mater Med 2008;19(5):2029-38.
18. Waldman SD, Grynpas MD, Pilliar RM, Kandel RA. Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro. J Biomed Mater Res 2002;62(3):323-30.
19. Pilliar RM, Kandel RA, Grynpas MD, Zalzal P, Hurtig M. Osteochondral defect repair using a novel tissue engineering approach: sheep model study. Technol Health Care 2007;15(1):47-56.
20. Allan KS, Pilliar RM, Wang J, Grynpas MD, Kandel RA. Formation of biphasic constructs containing cartilage with a calcified zone interface. Tissue Eng 2007;13(1):167-77.
21. Mente PL, Lewis JL. Elastic modulusof calcified cartilageisanorderofmagnitude less than that of subchondral bone. J Orthop Res 1994;12(5):637-47.
22. Ferguson VL, Bushby AJ, Boyde A. Nanomechanical properties and mineral concentration in articular calcified cartilage and subchondral bone. J Anat 2003;203(2):191-202.
23. Kandel R, Hurtig M, Grynpas M. Characterization of the mineral in calcified articular cartilagenous tissue formed in vitro. Tissue Eng 1999;5(1):25-34.
24. Zizak I, Roschger P, Paris O, Misof BM, Berzlanovich A, Bernstorff S, et al. Characteristics of mineral particles in the human bone/cartilage interface. J Struct Biol 2003;141(3):208-17.
25. Gupta HS, Schratter S, Tesch W, Roschger P, Berzlanovich A, Schoeberl T, et al. Two different correlations between nanoindentation modulus and mineral content in the bone-cartilage interface. J Struct Biol 2005;149(2):138-48.
26. Jager I, Fratzl P. Mineralized collagen fibrils: a mechanical model with a staggered arrangement of mineral particles. Biophys J 2000;79(4):1737-46.
27. Oegema Jr TR, Carpenter RJ, Hofmeister F, Thompson Jr RC. The interaction of the zone of calcified cartilage and subchondral bone in osteoarthritis. Microsc Res Tech 1997;37(4):324-32.
28. Kandel RA, Boyle J, Gibson G, Cruz T, Speagle M. In vitro formation of mineralized cartilagenous tissue by articular chondrocytes. In Vitro Cell Dev Biol Anim 1997;33(3):174-81.
29. Yu H, Grynpas M, Kandel RA. Composition of cartilagenous tissue with mineralized and non-mineralized zones formed in vitro. Biomaterials 1997;18(21):1425-31.
30. Fleisch H, Neuman WF. Mechanisms of calcification: role of collagen, polyphosphates, and phosphatase. Am J Physiol 1961;200(6):1296-300.
31. Francis MD. The inhibition of calcium hydroxypatite crystal growth by polyphosphonates and polyphosphates. Calcif Tissue Res 1969;3(2):151-62.
32. Fleisch H, Russell RG, Straumann F. Effect of pyrophosphate on hydroxyapatite and its implications in calcium homeostasis. Nature 1966;212(5065):901-3.
33. Fleisch H, Schibler D, Maerki J, Frossard I. Inhibition of aortic calcification by meansofpyrophosphate and polyphosphates. Nature 1965;207(5003):1300-1.
34. Irving JT, Schibler D, Fleisch H. Effect of condensed phosphates on vitamin D-induced aortic calcification in rats. Proc Soc Exp Biol Med 1966;122(3):852-6.
35. Schibler D, Fleisch H. Inhibition of skin calcification (calciphylaxis) by polyphosphates. Experientia 1966;22(6):367-9.
36. Omelon S, Baer A, Coyle T, Pilliar RM, Kandel R, Grynpas M. Polymeric crystallization and condensation of calcium polyphosphate glass. Mater Sci Bull 2008;43(1):68-80.
37. Pilliar RM, Filiaggi MJ, Wells JD, Grynpas MD, Kandel RA. Porous calcium polyphosphate scaffolds for bone substitute applications-in vitro characterization. Biomaterials 2001;22(9):963-72.
38. Allan RA, Miller JJ. Influence of S-adenosylmethionine on DAPI-induced fluorescence of polyphosphate in the yeast vacuole. Can J Microbiol 1980;26(8):912-20.
39. Tijssen JP, Beekes HW, Van Steveninck J. Localization of polyphosphates in Saccharomyces fragilis, as revealed by 4', 6-diamidino-2-phenylindole fluorescence. Biochim Biophys Acta 1982;721(4):394-8.
40. Lorenz B, Munkner J, Oliveira MP, Kuusksalu A, Leitao JM, Muller WE, et al. Changes in metabolism of inorganic polyphosphate in rat tissues and human cells during development and apoptosis. Biochim Biophys Acta 1997;1335(1-2):51-60.
41. Fleisch H, Straumann F, Schenk R, Bisaz S, Allgower M. Effect of condensed phosphates on calcification of chick embryo femurs in tissue culture. Am J Physiol 1966;211(3):821-5.
42. Kawazoe Y, Shiba T, Nakamura R, Mizuno A, Tsutsumi K, Uematsu T, et al. Induction of calcification in MC3T3-E1 cells by inorganic polyphosphate. J Dent Res 2004;83(8):613-8.
43. Omelon S, Georgiou J, Henneman ZJ, Wise LM, Sukhu B, Hunt T, et al. Control of vertebrate skeletal mineralization by polyphosphates. PLoS One 2009;4(5):e5634.
44. Schroder HC, Kurz L, Muller WE, Lorenz B. Polyphosphate in bone. Biochemistry (Mosc) 2000;65(3):296-303.
45. Smith SA, Mutch NJ, Baskar D, Rohloff P, Docampo R, Morrissey JH. Polyphosphate modulates blood coagulation and fibrinolysis. Proc Natl Acad Sci USA 2006;103(4):903-8.
46. Smith SA, Morrissey JH. Polyphosphate enhances fibrin clot structure. Blood 2008;112(7):2810-6.
47. Smith SA, Morrissey JH. Polyphosphate as a general procoagulant agent. J Thromb Haemost 2008;6(10):1750-6.
48. Kawazoe Y, Katoh S, Onodera Y, Kohgo T, Shindoh M, Shiba T. Activation of the FGF signaling pathway and subsequent induction of mesenchymal stem cell differentiation by inorganic polyphosphate. Int J Biol Sci 2008;4(1):37-47.
49. Shiba T, Nishimura D, Kawazoe Y, Onodera Y, Tsutsumi K, Nakamura R, et al. Modulation of mitogenic activity of fibroblast growth factors by inorganic polyphosphate. J Biol Chem 2003;278(29):26788-92.
50. Wang L, Fraley CD, Faridi J, Kornberg A, Roth RA. Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells. Proc Natl Acad Sci USA 2003;100(20):11249-54.
51. Leyhausen G, Lorenz B, Zhu H, Geurtsen W, Bohnensack R, Muller WE, et al. Inorganic polyphosphate in human osteoblast-like cells. J Bone Miner Res 1998;13(5):803-12.