Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions

International Journal of Cancer

Volumn 127, Issue 7, 2010, Pages 1718-1726

  Laxmi, Y R Santosh ^a   Liu, Xiaoping ^a   Suzuki, Naomi ^a   Kim, Sung Yeon ^a,c   Okamoto, Kanako ^a   Kim, Hyo Jeong ^a   Zhang, Guangxiang ^b   Chen, John J ^b   Okamoto, Yoshinori ^a,d   Shibutani, Shinya ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c Wonkwang University   (South Korea)

^d MEIJO UNIVERSITY   (Japan)

Author keywords

Antiestrogen; Antitumor; Breast cancer; Genotoxicity; Uterotrophic activity

Indexed keywords

(2E) 3 [4 [(Z) 4 CHLORO 1,2 DIPHENYLBUT 1 ENYL]PHENYL]ACRYLIC ACID; 2E 3 [4 [(E) 4 CHLORO 1 (4 HYDROXYPHENYL) 2 PHENYLBUT 1 ENYL] PHENYL] ACRYLIC ACID; 4 (1,2 DIPHENYL 1 BUTENYL)CINNAMIC ACID; ANTIESTROGEN; ANTINEOPLASTIC AGENT; OSPEMIFENE; RALOXIFENE; SS 1020; TAMOXIFEN; UNCLASSIFIED DRUG; 7,12 DIMETHYLBENZ[A]ANTHRACENE; DRUG DERIVATIVE; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER PREVENTION; CONTROLLED STUDY; DRUG SAFETY; DRUG SYNTHESIS; ESTROGEN ACTIVITY; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TUMOR XENOGRAFT; ANIMAL; CHEMICALLY INDUCED DISORDER; DNA ADDUCT; DRUG EFFECT; ENDOMETRIUM TUMOR; EXPERIMENTAL NEOPLASM; PHYSIOLOGY; RAT; SYNTHESIS; UTERUS;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; DNA ADDUCTS; ENDOMETRIAL NEOPLASMS; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR MODULATORS; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; RATS; TAMOXIFEN; UTERUS;

EID: 77956607139     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25167     Document Type: Article

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