Evidence of cognitive and neurophysiological impairment in patients with untreated naive acromegaly

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 9, 2010, Pages 4367-4379

  Leon Carrion, José ^a   Martin Rodriguez, Juan Francisco ^a   Madrazo Atutxa, Ainara ^b   Soto Moreno, Alfonso ^b   Venegas Moreno, Eva ^b   Torres Vela, Elena ^c   Benito López, Pedro ^d   Gálvez, Maria Ángeles ^d   Tinahones, Francisco J ^e   Leal Cerro, Alfonso ^b  

^a UNIVERSITY OF SEVILLE   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^c HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^d HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^e HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; ESTRADIOL; FOLLITROPIN; GROWTH HORMONE; LUTEINIZING HORMONE; PROLACTIN; SOMATOMEDIN C; TESTOSTERONE; THYROTROPIN; THYROXINE;

ACROMEGALY; ADENOMA; ADULT; ARTICLE; ATTENTION; BRAIN FUNCTION; BRAIN TOMOGRAPHY; CLINICAL ARTICLE; COGNITION; COMPARATIVE STUDY; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DEPRESSION; ELECTROENCEPHALOGRAM; EMOTION; ESTRADIOL BLOOD LEVEL; FEMALE; FOLLITROPIN BLOOD LEVEL; FRONTAL CORTEX; GROWTH HORMONE BLOOD LEVEL; HUMAN; LONG TERM MEMORY; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MEMORY; MEMORY DISORDER; POSITIVE END EXPIRATORY PRESSURE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; QUALITY OF LIFE; QUANTITATIVE ANALYSIS; SHORT TERM MEMORY; TEMPORAL CORTEX; TESTOSTERONE BLOOD LEVEL; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TUMOR VOLUME; VERBAL MEMORY; VISUAL MEMORY; BRAIN DISEASES; COGNITION DISORDERS; COMPLICATION; CONTROLLED CLINICAL TRIAL; MEMORY DISORDERS; MIDDLE AGED; NEUROPHYSIOLOGY; NEUROPSYCHOLOGICAL TEST; PHYSIOLOGY; PROCEDURES; TASK PERFORMANCE; YOUNG ADULT;

ACROMEGALY; ADULT; ATTENTION; BRAIN DISEASES; COGNITION; COGNITION DISORDERS; FEMALE; HUMANS; MALE; MEMORY; MEMORY DISORDERS; MIDDLE AGED; NEUROPHYSIOLOGY; NEUROPSYCHOLOGICAL TESTS; TASK PERFORMANCE AND ANALYSIS; YOUNG ADULT;

EID: 77956583410     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-0394     Document Type: Article

References (50)

1. Colao A, Ferone D, Marzullo P, Lombardi G 2004 Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev 25:102-152 (Pubitemid 38269977)
2. O'Kusky JR, Ye P, D'Ercole AJ 2000 Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. J Neurosci 20:8435-8442
3. Lai ZN, Emtner M, Roos P, Nyberg F 1991 Characterization of putative growth hormone receptors in human choroid plexus. Brain Res 546:222-226
4. Chung YH, Shin CM, Joo KM, Kim MJ, Cha CI 2002 Region-specific alterations in insulin-like growth factor receptor type I in the cerebral cortex and hippocampus of aged rats. Brain Res 946:307-313
5. van Dam PS, Aleman A, de Vries WR, Deijen JB, van der Veen EA, de Haan EH, Koppeschaar HP 2000 Growth hormone, insulin-like growth factor I and cognitive function in adults. Growth Horm IGF Res(Suppl B):S69-S73 (Pubitemid 30637220)
6. Tolis G, Angelopoulos NG, Katounda E, Rombopoulos G, Kaltzidou V, Kaltsas D, Protonotariou A, Lytras A 2006 Medical treatment of acromegaly: comorbidities and their reversibility by somatostatin analogs. Neuroendocrinology 83:249-257 (Pubitemid 44578879)
7. Falleti MG, Maruff P, Burman P, Harris A 2006 The effects of growth hormone (GH) deficiency and GH replacement on cognitive performance in adults: a meta-analysis of the current literature. Psychoneuroendocrinology 31:681-691
8. Tanriverdi F, Yapislar H, Karaca Z, Unluhizarci K, Suer C, Kelestimur F 2009 Evaluation of cognitive performance by using P300 auditory event related potentials (ERPs) in patients with growth hormone (GH) deficiency and acromegaly. Growth Horm IGF Res 19:24-30
9. Sievers C, Sämann PG, Dose T, Dimopoulou C, Spieler D, Roemmler J, Schopohl J, Mueller M, Schneider HJ, Czisch M, Pfister H, Stalla GK 2009 Macroscopic brain architecture changes and white matter pathology in acromegaly: a clinico-radiological study. Pituitary 12:177-185
10. Rowles SV, Prieto L, Badia X, Shalet SM, Webb SM, Trainer PJ 2005 Quality of life (QOL) in patients with acromegaly is severely impaired: use of a novel measure of QOL: acromegaly quality of life questionnaire. J Clin Endocrinol Metab 90:3337-3341 (Pubitemid 41014295)
11. Sievers C, Dimopoulou C, Pfister H, Lieb R, Steffin B, Roemmler J, Schopohl J, Mueller M, Schneider HJ, Ising M, Wittchen HU, Stalla GK 2009 Prevalence of mental disorders in acromegaly: a cross-sectional study in 81 acromegalic patients. Clin Endocrinol (Oxf) 71:691-701
12. Werner S 2006 Acromegaly and brain function: effects on the human brain during conditions with increased growth hormone concentrations. In: Nyberg F, ed. The somatotrophic axis in brain function. San Diego: Elsevier Academic Press; 267-270
13. Leal-Cerro A, Flores JM, Rincon M, Murillo F, Pujol M, Garcia-Pesquera F, Dieguez C, Casanueva FF 2005 Prevalence of hypopituitarism and growth hormone deficiency in adults long-term after severe traumatic brain injury. Clin Endocrinol (Oxf) 62:525-532 (Pubitemid 40646717)
14. Lezak M 1995 Neuropsychological assessment. New York: Oxford University Press
15. León-Carrión J, Atutxa AM, Mangas MA, Soto-Moreno A, Pumar A, Leon-Justel A, Martín-Rodriguez JF, Venegas E, Domínguez- Morales MR, Leal-Cerro A 2009 A clinical profile of memory impairment in humans due to endogenous glucocorticoid excess. Clin Endocrinol (Oxf) 70:192-200
16. Wechsler D 1997 WAlS-III/WMS-III technical manual. San Antonio, TX: Psychological Corporation
17. Benton AL, Hamsher KD 1976 Multilingual Aphasia Examination. Iowa City, IA: University of Iowa
18. Beck AT, Steer RA, Brown GK 1996 Manual for the Beck Depression Inventory-II. San Antonio, TX: Psychological Corporation
19. Spalletta G, Ripa A, Caltagirone C 2005 Symptom profile of DSM-IV major and minor depressive disorders in first-ever stroke patients. Am J Geriatr Psychiatry 13:108-115 (Pubitemid 41031099)
20. Sanz J, Vazquez C 1998 [Reliability, validity, and normative data of the Beck Depression Inventory]. Psicothema 10:303-318
21. Badia X, Webb SM, Prieto L, Lara N 2004 Acromegaly Quality of Life Questionnaire (AcroQoL). Health Qual Life Outcomes 2:13 (Pubitemid 39112017)
22. Delorme A, Makeig S 2004 EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J Neurosci Methods 134:9-21 (Pubitemid 38224183)
23. Pascual-Marqui RD, Michel CM 1994 LORETA (low resolution brain electromagnetic tomography) new authentic 3D functional images of the brain. ISBET Newsletter 5:4-8
24. Babiloni C, Binetti G, Cassetta E, Cerboneschi D, Dal Forno G, Del Percio C, Ferreri F, Ferri R, Lanuzza B, Miniussi C, Moretti DV, Nobili F, Pascual-Marqui RD, Rodriguez G, Romani GL, Salinari S, Tecchio F, Vitali P, Zanetti O, Zappasodi F, Rossini PM 2004 Mapping distributed sources of cortical rhythms in mild Alzheimer's disease. Amulticentric EEG study. NeuroImage 22:57-67
25. Leon-Carrion J, Martin-Rodriguez JF, Damas-Lopez J, Barroso y Martin JM, Dominguez-Morales MR 2008 Brain function in the minimally conscious state: a quantitative neurophysiological study. Clin Neurophysiol 119:1506-1514
26. Talairach J, Tournoux P 1988 Co-planar stereotaxic atlas of the human brain. New York: Thieme Medical Publishers
27. Granada ML, Ulied A, Casanueva FF, Pico A, Lucas T, Torres E, Sanmartí A 2008 Serum IGF-I measured by four different immunoassays in patients with adult GH deficiency or acromegaly and in a control population. Clin Endocrinol (Oxf) 68:942-950
28. Cohen J 1992 A power primer. Psychol Bull 112:155-159
29. Zola-Morgan S, Squire LR 1993 Neuroanatomy of memory. Annu Rev Neurosci 16:547-563
30. Richert S, Strauss A, Fahlbusch R, Oeckler R, von Werder K 1987 [Psychopathologic symptoms and personality traits in patients with florid acromegaly] (in German). Schweiz Arch Neurol Psychiatr 138:61-86
31. Pantanetti P, Sonino N, Arnaldi G, Boscaro M 2002 Self image and quality of life in acromegaly. Pituitary 5:17-19
32. Owen AM 2000 The role of the lateral frontal cortex in mnemonic processing: the contribution of functional neuroimaging. Exp Brain Res 133:33-43
33. Canavan AG, Passingham RE, Marsden CD, Quinn N, Wyke M, Polkey CE 1989 Sequence ability in Parkinsonians, patients with frontal lobe lesions and patients who have undergone unilateral temporal lobectomies. Neuropsychologia 27:787-798
34. Maeshima S, Nakai K, Itakura T, Komai N, Dohi N 1997 Exploratory-motor task to evaluate right frontal lobe damage. Brain Inj 11:211-227
35. Hornberger M, Piguet O, Kipps C, Hodges JR 2008 Executive function in progressive and nonprogressive behavioural variant frontotemporal dementia. Neurology 71:1481-1488
36. Gilboa A, Moscovitch M 2002 The cognitive neuroscience of confabulation: a review and a model. In: Baddeley AD, Kopelman MD, Wilson BA, eds. Handbook of memory disorders. 2nd ed. London: Wiley: 315-342
37. Turner MS, Cipolotti L, Yousry TA, Shallice T 2008 Confabulation: damage to a specific inferior medial prefrontal system. Cortex 44:637-648
38. Dudai Y 2004 The neurobiology of consolidations, or, how stable is the engram? Annu Rev Psychol 55:51-86
39. Henson RN, Shallice T, Dolan RJ 1999 Right prefrontal cortex and episodic memory retrieval: a functional MRI test of the monitoring hypothesis. Brain 122:1367-1381
40. Fletcher PC, Shallice T, Frith CD, Frackowiak RS, Dolan RJ 1998 The functional roles of prefrontal cortex in episodic memory. II. Retrieval. Brain 121:1249-1256
41. Bigler ED 2003 Neuroimaging and the ROCF. In: Knight JA, Kaplan E, eds. The handbook of Rey-Osterrieth complex figure usage: clinical and research applications. Lutz, FL: Psychological Assessment Resources; 323-334
42. Serra-Grabulosa JM, Junqué C, Verger K, Salgado-Pineda P, Mañeru C, Mercader JM 2005 Cerebral correlates of declarative memory dysfunctions in early traumatic brain injury. J Neurol Neurosurg Psychiatry 76:129-131
43. Bartke A 2003 Can growth hormone accelerate aging? Evidence from GH-transgenic mice. Neuroendocrinology 78:210-216
44. Webb SM, Badia X, Surinach NL, for the Spanish AcroQoL Study Group 2006 Validity and clinical applicability of the Acromegaly Quality of Life Questionnaire (AcroQoL): a six months prospective study. Eur J Endocrinol 155:269-277
45. Biermasz NR, van Thiel SW, Pereira AM, Hoftijzer HC, van Hemert AM, Smit JW, Romijn JA, Roelfsema F 2004 Decreased quality of life in patients with acromegaly despite long-term cure of growth hormone excess. J Clin Endocrinol Metab 89:5369-5376
46. Moore MJ, Moore PB, Shaw PJ 1998 Mood disturbance in motor neurone disease. J Neurol Sci 160:S53-S56
47. Steriade M, Amzica F, Contreras D 1996 Synchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation. J Neurosci 16:392-417
48. Jelic V, Johansson SE, Almkvist O, Shigeta M, Julin P, Nordberg A, Winblad B, Wahlund LO 2000 Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease. Neurobiol Aging 21:533-540
49. Thatcher RW, Walker RA, Gerson I, Geisler FH 1989 EEG discriminant analyses of mild head trauma. Electroencephalogr Clin Neurophysiol 73:94-106
50. Blumenfeld RS, Ranganath C 2006 Dorsolateral prefrontal cortex promotes long-term memory formation through its role in working memory organization. J Neurosci 26:916-925