Gene regulation: Enhancers stepping out of the shadow

Current Biology

Volumn 20, Issue 17, 2010, Pages

  Hobert, Oliver ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 77956546074     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.07.035     Document Type: Short Survey

References (14)

1. C.H. Waddington Canalization of development and the inheritance of acquired characters Nature 150 1942 563 565
2. V. Hamburger The Heritage of Experimental Embryology: Hans Spemann and the Organizer 1988 Oxford University Press Oxford
3. A.S. Wilkins Canalization: a molecular genetic perspective Bioessays 19 1997 257 262
4. E. Hornstein, and N. Shomron Canalization of development by microRNAs Nat. Genet. 38 Suppl 2006 S20 S24
5. J.W. Hong, D.A. Hendrix, and M.S. Levine Shadow enhancers as a source of evolutionary novelty Science 321 2008 1314
6. M.W. Perry, A.N. Boettiger, J.P. Bothma, and M.S. Levine Shadow enhancers foster robustness of Drosophila gastrulation Curr. Biol. 20 2010 1562 1567
7. N. Frankel, G.K. Davis, D. Vargas, S. Wang, F. Payre, and D.L. Stern Phenotypic robustness conferred by apparently redundant transcriptional enhancers Nature 466 2010 490 493
8. W. Scharloo Canalization: Genetic and developmental aspects Annu. Rev. Ecol. Sys. 22 1991 65 93
9. M.M. O'Meara, H. Bigelow, S. Flibotte, J.F. Etchberger, D.G. Moerman, and O. Hobert Cis-regulatory mutations in the Caenorhabditis elegans Homeobox gene locus cog-1 affect neuronal development Genetics 181 2009 1679 1686
10. Y. Jeong, K. El-Jaick, E. Roessler, M. Muenke, and D.J. Epstein A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers Development 133 2006 761 772
11. T. Werner, A. Hammer, M. Wahlbuhl, M.R. Bosl, and M. Wegner Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis Nucleic Acids Res. 35 2007 6526 6538
12. N. Xiong, C. Kang, and D.H. Raulet Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development Immunity 16 2002 453 463
13. H.E. Bülow, and O. Hobert Differential sulfations and epimerization define heparan sulfate specificity in nervous system development Neuron 41 2004 723 736
14. A. Raj, S.A. Rifkin, E. Andersen, and A. van Oudenaarden Variability in gene expression underlies incomplete penetrance Nature 463 2010 913 918