-
1
-
-
40749106310
-
Juvenile idiopathic arthritis
-
th Edition). Cassidy JT, Petty RE (Eds). WB Saunders, PA, USA
-
th Edition). Cassidy JT, Petty RE (Eds). WB Saunders, PA, USA, 291-303 (2005).
-
(2005)
Textbook of Pediatric Rheumatology
, pp. 291-303
-
-
Cassidy, J.T.1
Petty, R.E.2
-
2
-
-
13544273826
-
Macrophage activation syndrome: Characteristic fndings on liver biopsy illustrating the key role of activated IFN-y-producing lymphocytes and IL-6-and TNF-a-producing macrophages
-
Billiau AD, Roskams T, Van Damme-Lombaerts R, Matthys P, Wouters C. Macrophage activation syndrome: characteristic fndings on liver biopsy illustrating the key role of activated IFN-y-producing lymphocytes and IL-6-and TNF-a-producing macrophages. Blood 105, 1648-1651 (2005).
-
(2005)
Blood
, vol.105
, pp. 1648-1651
-
-
Billiau, A.D.1
Roskams, T.2
Van Damme-Lombaerts, R.3
Matthys, P.4
Wouters, C.5
-
3
-
-
0036905481
-
Long-term follow-up of 246 adults with juvenile idiopathic arthritis: Predictive factors for mood and pain
-
Packham JC, Hall MA, Pimm TJ. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: predictive factors for mood and pain. Rheumatology (Oxford) 41, 1444-1449 (2002).
-
(2002)
Rheumatology (Oxford)
, vol.41
, pp. 1444-1449
-
-
Packham, J.C.1
Hall, M.A.2
Pimm, T.J.3
-
4
-
-
47249152715
-
How the study of children with rheumatic diseases identifed interferon a and interleukin 1 as novel therapeutic targets
-
Pascual V, Allantaz F, Patel P et al How the study of children with rheumatic diseases identifed interferon a and interleukin 1 as novel therapeutic targets. Immunol. Rev. 223, 39-59 (2008).
-
(2008)
Immunol. Rev.
, vol.223
, pp. 39-59
-
-
Pascual, V.1
Allantaz, F.2
Patel, P.3
-
5
-
-
77950531755
-
Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis
-
Vastert SJ, van Wijk R, D'Urbano LE et al Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis. Rheumatology 49, 441-449 (2010).
-
(2010)
Rheumatology
, vol.49
, pp. 441-449
-
-
Vastert, S.J.1
Van Wijk, R.2
D'Urbano, L.E.3
-
6
-
-
69449093422
-
Defective phosphorylation of interleukin-18 receptor b causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis
-
De Jager W, Vastert SJ, Beekman JM et al Defective phosphorylation of interleukin-18 receptor b causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 60, 2782-2793 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 2782-2793
-
-
De Jager, W.1
Vastert, S.J.2
Beekman, J.M.3
-
7
-
-
0026014522
-
Correlation of interleukin-6 levels with joint involvement and thrombocytosis in patients with systemic juvenile rheumatoid arthritis
-
De Benedetti F, Massa M, Robbioni P. Correlation of interleukin-6 levels with joint involvement and thrombocytosis in patients with systemic juvenile rheumatoid arthritis. Arthritis Rheum. 34, 1158-1163 (1991).
-
(1991)
Arthritis Rheum.
, vol.34
, pp. 1158-1163
-
-
De Benedetti, F.1
Massa, M.2
Robbioni, P.3
-
8
-
-
0037292517
-
Growth impairment in IL-6-overexpressing transgenic mice is associated with induction of SOCS3 mRNA
-
Lieskovska J, Guo D, Derman E. Growth impairment in IL-6-overexpressing transgenic mice is associated with induction of SOCS3 mRNA. Growth Horm. IGF Res. 13, 26-35 (2003).
-
(2003)
Growth Horm. IGF Res.
, vol.13
, pp. 26-35
-
-
Lieskovska, J.1
Guo, D.2
Derman, E.3
-
9
-
-
71749093502
-
Systemic JIA: New development in the understanding of the pathophysiology and therapy
-
Vastert SJ, Kuis W, Grom AA. Systemic JIA: new development in the understanding of the pathophysiology and therapy. Best Pract. Res. Clin. Rheumatol 23, 655-664 (2009).
-
(2009)
Best Pract. Res. Clin. Rheumatol
, vol.23
, pp. 655-664
-
-
Vastert, S.J.1
Kuis, W.2
Grom, A.A.3
-
10
-
-
46049110547
-
Interleukin (IL)-6 and IL-1p act synergistically within the brain to induce sickness behavior and fever in rats
-
Harden LM, du Plessis I, Poole S et al Interleukin (IL)-6 and IL-1p act synergistically within the brain to induce sickness behavior and fever in rats. Brain Behav. Immun. 22, 838-849 (2008).
-
(2008)
Brain Behav. Immun.
, vol.22
, pp. 838-849
-
-
Harden, L.M.1
Du Plessis, I.2
Poole, S.3
-
11
-
-
62849089145
-
Role of interleukin-6 in the anemia of chronic disease
-
Raj DSC. Role of interleukin-6 in the anemia of chronic disease. Semin. Arthritis Rheum. 38, 382-388 (2009).
-
(2009)
Semin. Arthritis Rheum.
, vol.38
, pp. 382-388
-
-
Dsc, R.1
-
13
-
-
27644549634
-
Essential role of STAT3 in cytokine-driven NF-KB-mediated serum amyloid A gene expression
-
Hagihara K, Nishikawa T, Sugamata Y et al Essential role of STAT3 in cytokine-driven NF-KB-mediated serum amyloid A gene expression. Genes Cells 10, 1051-1063 (2005).
-
(2005)
Genes Cells
, vol.10
, pp. 1051-1063
-
-
Hagihara, K.1
Nishikawa, T.2
Sugamata, Y.3
-
14
-
-
49149095841
-
Transcriptional complex formation of c-Fos STAT3 and hepatocyte NF-1a is essential for cytokine-driven C-reactive protein gene expression
-
Nishikawa T, Hagihara K, Serada S et al Transcriptional complex formation of c-Fos, STAT3, and hepatocyte NF-1a is essential for cytokine-driven C-reactive protein gene expression. J. Immunol. 180, 3492-3501 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 3492-3501
-
-
Nishikawa, T.1
Hagihara, K.2
Serada, S.3
-
15
-
-
0023942493
-
Interleukin-6 in synovial fuid and serum of patients with rheumatoid arthritis and other infammatory arthritides
-
Houssiau FA, Devogelaer JP, Van Damme J, de Deuxchaisnes CN, Van Snick J. Interleukin-6 in synovial fuid and serum of patients with rheumatoid arthritis and other infammatory arthritides. Arthritis Rheum. 31, 784-788 (1988).
-
(1988)
Arthritis Rheum.
, vol.31
, pp. 784-788
-
-
Houssiau, F.A.1
Devogelaer, J.P.2
Van Damme, J.3
De Deuxchaisnes, C.N.4
Van Snick, J.5
-
16
-
-
0024459013
-
Pathogenic signifcance of interleukin-6 (IL-6/BSF-2) in Castlemans disease
-
Yoshizaki K, Matsuda T, Nishimoto N et al Pathogenic signifcance of interleukin-6 (IL-6/BSF-2) in Castlemans disease. Blood 74, 1360-1367 (1989).
-
(1989)
Blood
, vol.74
, pp. 1360-1367
-
-
Yoshizaki, K.1
Matsuda, T.2
Nishimoto, N.3
-
17
-
-
0036898472
-
Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Stills disease
-
Iwamoto M, Nara H, Hirata D, Minota S, Nishimoto N, Yoshizaki K. Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Stills disease. Arthritis Rheum. 46, 3388-3389 (2002).
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3388-3389
-
-
Iwamoto, M.1
Nara, H.2
Hirata, D.3
Minota, S.4
Nishimoto, N.5
Yoshizaki, K.6
-
18
-
-
0027502201
-
Reshaping a human antibody to inhibit the interleukin-6-dependent tumor cell growth
-
Sato K, Tsuchiya, Saldanha J et al. Reshaping a human antibody to inhibit the interleukin-6-dependent tumor cell growth. Cancer Res. 53, 851-856 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 851-856
-
-
Sato, K.1
Tsuchiya Saldanha, J.2
-
19
-
-
20144362101
-
Therapeutic effcacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis
-
Yokota S, Miyame T, Imagawa T et al Therapeutic effcacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 52, 818-825 (2005).
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 818-825
-
-
Yokota, S.1
Miyame, T.2
Imagawa, T.3
-
20
-
-
40749152243
-
Effcacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: A randomized, double-blind, placebo-controlled, withdrawal Phase III trial
-
Yokota S, Imagawa T, Mori M et al Effcacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomized, double-blind, placebo-controlled, withdrawal Phase III trial. Lancet 371, 998-1006 (2008).
-
(2008)
Lancet
, vol.371
, pp. 998-1006
-
-
Yokota, S.1
Imagawa, T.2
Mori, M.3
-
21
-
-
14944373440
-
Targeting the interleukin-6 receptor: A new treatment for systemic juvenile idiopathic arthritis?
-
De Benedetti F, Martini A. Targeting the interleukin-6 receptor: a new treatment for systemic juvenile idiopathic arthritis? Arthritis Rheum. 52, 687-693 (2005).
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 687-693
-
-
De Benedetti, F.1
Martini, A.2
-
22
-
-
18644385243
-
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical aspect to IL-1 blockade
-
Pascual V, Allantaz F, Arce E et al. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical aspect to IL-1 blockade. J. Exp. Med. 201, 1479-1486 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1479-1486
-
-
Pascual, V.1
Allantaz, F.2
Arce, E.3
-
23
-
-
35649001064
-
Macrophage activation syndrome during anti-IL1 receptor therapy (anakinra) in a patient affected by systemic-onset idiopathic juvenile arthritis
-
Lurati A, Teruzzi B, Salmaso A et al Macrophage activation syndrome during anti-IL1 receptor therapy (anakinra) in a patient affected by systemic-onset idiopathic juvenile arthritis. Paed. Rheumatol. Online 3, 79-85 (2005).
-
(2005)
Paed. Rheumatol. Online
, vol.3
, pp. 79-85
-
-
Lurati, A.1
Teruzzi, B.2
Salmaso, A.3
-
24
-
-
39549109506
-
Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: Preliminary experience in France
-
Lequerre T, Quarties F, Rosellini D et al Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France. Ann. Rheum. Dis. 67, 302-308 (2008).
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 302-308
-
-
Lequerre, T.1
Quarties, F.2
Rosellini, D.3
-
25
-
-
10744230484
-
International League of Association for Rheumatology. International League Association for Rheumatology classifcation of juvenile idiopathic arthritis: Second revision, Edmonton
-
Petty RE, Southwood TR, Manners P et al International League of Association for Rheumatology. International League Association for Rheumatology classifcation of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J. Rheumatol. 31, 390-392 (2004).
-
(2001)
J. Rheumatol.
, vol.31
, pp. 390-392
-
-
Petty, R.E.1
Southwood, T.R.2
Manners, P.3
-
26
-
-
0343415576
-
Final height, armspan, subischial leg length and body proportion in juvenile chronic arthritis: A long-term follow-up study
-
Zak M, Muller J, Karup Pedersen F. Final height, armspan, subischial leg length and body proportion in juvenile chronic arthritis: a long-term follow-up study. Horm. Res. 52, 80-85 (1999).
-
(1999)
Horm. Res.
, vol.52
, pp. 80-85
-
-
Zak, M.1
Muller, J.2
Karup Pedersen, F.3
-
27
-
-
67650594920
-
Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells
-
Nakajima S, Naruto T, Miyamae T, Imagawa T, Mori M, Nishimaki S, Yokota S. Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells. Cytokine 47, 91-97 (2009).
-
(2009)
Cytokine
, vol.47
, pp. 91-97
-
-
Nakajima, S.1
Naruto, T.2
Miyamae, T.3
Imagawa, T.4
Mori, M.5
Nishimaki, S.6
Yokota, S.7
-
28
-
-
44349141890
-
Longterm outcome of amyloidosis associated with juvenile idiopathic arthritis
-
Immonen K, Savolainen A, Kautiainen H, Hakala M. Longterm outcome of amyloidosis associated with juvenile idiopathic arthritis. J. Rheumatol. 35, 907-912 (2008).
-
(2008)
J. Rheumatol.
, vol.35
, pp. 907-912
-
-
Immonen, K.1
Savolainen, A.2
Kautiainen, H.3
Hakala, M.4
-
29
-
-
33745726721
-
Macrophage activation syndrome in juvenile idiopathic arthritis
-
Cortis E, Insalaco A. Macrophage activation syndrome in juvenile idiopathic arthritis. Acta Pediatr. Suppl. 95, 38-41 (2005).
-
(2005)
Acta Pediatr. Suppl.
, vol.95
, pp. 38-41
-
-
Cortis, E.1
Insalaco, A.2
-
30
-
-
1542283765
-
Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis?
-
Grom AA. Natural killer cell dysfunction: a common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis? Arthritis Rheum. 50, 689-698 (2004).
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 689-698
-
-
Grom, A.A.1
-
31
-
-
77949704386
-
Hemophagocytic lymphohistiocytosis: When the immune system runs amok
-
Janka G. Hemophagocytic lymphohistiocytosis: when the immune system runs amok. Klin. Padiatr. 221, 278-285 (2009).
-
(2009)
Klin. Padiatr.
, vol.221
, pp. 278-285
-
-
Janka, G.1
-
32
-
-
0024155507
-
Molecular regulation of B lymphocyte response
-
Kishimoto T, Hirano T. Molecular regulation of B lymphocyte response. Annu. Rev. Immunol. 6, 485-512 (1988).
-
(1988)
Annu. Rev. Immunol.
, vol.6
, pp. 485-512
-
-
Kishimoto, T.1
Hirano, T.2
-
33
-
-
0031913593
-
Interleukin-6 and its receptor: Ten years later
-
Hirano T. Interleukin-6 and its receptor: ten years later. Int. Rev. Immunol. 16, 249-284 (1998).
-
(1998)
Int. Rev. Immunol.
, vol.16
, pp. 249-284
-
-
Hirano, T.1
-
34
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga T, Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15, 797-819 (1997).
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
35
-
-
0030467394
-
Regulation of STAT-dependent pathway by growth factors and cytokines
-
Leaman DW, Leung S, Li X, Stark GR. Regulation of STAT-dependent pathway by growth factors and cytokines. FASEB J. 10, 1578-1588 (1996).
-
(1996)
FASEB J.
, vol.10
, pp. 1578-1588
-
-
Leaman, D.W.1
Leung, S.2
Li, X.3
Stark, G.R.4
-
36
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga T, Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Ann. Rev. Immunol. 15, 797-819 (1997).
-
(1997)
Ann. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
37
-
-
0030755904
-
Differences in synovial fuid cytokine levels between juvenile and adult rheumatoid arthritis
-
De Benedetti F, Pignati P, Gerloni V et al. Differences in synovial fuid cytokine levels between juvenile and adult rheumatoid arthritis. J. Rheumatol. 24, 1403-1409 (1997).
-
(1997)
J. Rheumatol.
, vol.24
, pp. 1403-1409
-
-
De Benedetti, F.1
Pignati, P.2
Gerloni, V.3
-
38
-
-
21344444154
-
Fever and hypothermia in systemic infammation: Recent discoveries and revisions
-
Romanovsky AA, Almeida MC, Aronoff DM et al. Fever and hypothermia in systemic infammation: recent discoveries and revisions. Front. Biosci. 10, 2193-2216 (2005).
-
(2005)
Front. Biosci.
, vol.10
, pp. 2193-2216
-
-
Romanovsky, A.A.1
Almeida, M.C.2
Aronoff, D.M.3
-
39
-
-
0034944705
-
Abnormal regulation of interleukin 6 in systemic juvenile idiopathic arthritis
-
Pignatti P, Vivarelli M, Meazza C, Rizzolo MG, Martini A, De Benedetti F. Abnormal regulation of interleukin 6 in systemic juvenile idiopathic arthritis. J. Rheumatol. 28, 1670-1676 (2001).
-
(2001)
J. Rheumatol.
, vol.28
, pp. 1670-1676
-
-
Pignatti, P.1
Vivarelli, M.2
Meazza, C.3
Rizzolo, M.G.4
Martini, A.5
De Benedetti, F.6
-
40
-
-
0041828636
-
Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: The same entities?
-
Grom AA. Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities? Curr. Opin Rheumatol. 15, 587-590 (2003).
-
(2003)
Curr. Opin Rheumatol.
, vol.15
, pp. 587-590
-
-
Grom, A.A.1
-
41
-
-
0035079003
-
Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis
-
Ravelli A, Caria MC, Buratti S et al. Methotrexate as a possible trigger of macrophage activation syndrome in systemic juvenile idiopathic arthritis. J. Rheumatol. 28, 865-867 (2001).
-
(2001)
J. Rheumatol.
, vol.28
, pp. 865-867
-
-
Ravelli, A.1
Caria, M.C.2
Buratti, S.3
-
42
-
-
33646485697
-
Macrophage activation syndrome is associated with lobular hepatitis and severe duct injury with cholestasis
-
Bihl F, Emmenegger U, Reichen J et al Macrophage activation syndrome is associated with lobular hepatitis and severe duct injury with cholestasis. J. Hepatol. 44, 1208-1212 (2006).
-
(2006)
J. Hepatol.
, vol.44
, pp. 1208-1212
-
-
Bihl, F.1
Emmenegger, U.2
Reichen, J.3
-
43
-
-
33646404916
-
The clinical spectrum and treatment options of macrophage activation syndrome in the pediatric age
-
Stabile A, Bertoni B, Ansuini V, La Torraca I, Salli A, Rigante D. The clinical spectrum and treatment options of macrophage activation syndrome in the pediatric age. Eur. Rev. Med. Pharmacol. Sci. 10, 53-59 (2006).
-
(2006)
Eur. Rev. Med. Pharmacol. Sci.
, vol.10
, pp. 53-59
-
-
Stabile, A.1
Bertoni, B.2
Ansuini, V.3
La Torraca, I.4
Salli, A.5
Rigante, D.6
-
44
-
-
0025801719
-
Iron-independent induction of ferritin H chain by tumor necrosis factor
-
Miller LL, Miller SC, Torti SV, Tsuji Y, Torti FM. Iron-independent induction of ferritin H chain by tumor necrosis factor. Proc. Natl Acad. Sci. USA 88, 4946-4950 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 4946-4950
-
-
Miller, L.L.1
Miller, S.C.2
Torti, S.V.3
Tsuji, Y.4
Torti, F.M.5
-
45
-
-
0023727257
-
Enhanced serum levels of p-2-microglobulin, neopterin, and interferon-y in patients treated with recombinant tumor necrosis factor - A
-
Aulitzky WE, Tilg H, Herold M, Berger M, Vogel W, Judmaier G. Enhanced serum levels of p-2-microglobulin, neopterin, and interferon-y in patients treated with recombinant tumor necrosis factor-a. J. Interferon Res. 8, 655-664 (1988).
-
(1988)
J. Interferon Res.
, vol.8
, pp. 655-664
-
-
Aulitzky, W.E.1
Tilg, H.2
Herold, M.3
Berger, M.4
Vogel, W.5
Judmaier, G.6
-
46
-
-
51449123602
-
Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF
-
Pucci B, Bertani F, Karpinich NO et al Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF. J. Cell. Physiol. 217, 442-449 (2008).
-
(2008)
J. Cell. Physiol.
, vol.217
, pp. 442-449
-
-
Pucci, B.1
Bertani, F.2
Karpinich, N.O.3
-
47
-
-
4344614641
-
Desensitization of the permeability transition pore by cyclosporin a prevents activation of the mitochondrial apoptotic pathway and liver damage by tumor necrosis factor - A
-
Soriano ME, Nicolosi L, Bernardi P. Desensitization of the permeability transition pore by cyclosporin a prevents activation of the mitochondrial apoptotic pathway and liver damage by tumor necrosis factor-a. J. Biol. Chem. 279, 36803-36808 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36803-36808
-
-
Soriano, M.E.1
Nicolosi, L.2
Bernardi, P.3
-
48
-
-
0023202754
-
Multiple effects of tumor necrosis factor on lipoprotein lipase in vivo
-
Semb H, Peterson J, Tavernier J, Olivecrona T. Multiple effects of tumor necrosis factor on lipoprotein lipase in vivo. J. Biol. Chem. 262(17), 8390-8394 (1987).
-
(1987)
J. Biol. Chem.
, vol.262
, Issue.17
, pp. 8390-8394
-
-
Semb, H.1
Peterson, J.2
Tavernier, J.3
Olivecrona, T.4
-
50
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi O, Hoshino K, Kawai T et al Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11, 443-451 (1999).
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
-
51
-
-
33747378491
-
Interleukin-6 and leptin mediate lipopolysaccharide-induced fever and sickness behavior
-
Harden LM, du Plessis I, Poole S, Laburn HP. Interleukin-6 and leptin mediate lipopolysaccharide-induced fever and sickness behavior. Physiol. Behav. 89, 146-155 (2006).
-
(2006)
Physiol. Behav.
, vol.89
, pp. 146-155
-
-
Harden, L.M.1
Du Plessis, I.2
Poole, S.3
Laburn, H.P.4
-
52
-
-
0141535338
-
Charcteristics of thermoregulatory and febrile responses in mice defant in prostaglandin EP1 and EP3 receptors
-
Oka T, Oka K, Kobayashi T et al. Charcteristics of thermoregulatory and febrile responses in mice defant in prostaglandin EP1 and EP3 receptors. J. Physiol. 551, 945-954 (2003).
-
(2003)
J. Physiol.
, vol.551
, pp. 945-954
-
-
Oka, T.1
Oka, K.2
Kobayashi, T.3
-
53
-
-
18644385612
-
IL-6 transsignaling: The in vivo consequences
-
Jones SA, Richards PJ, Scheller J, Rose-John S. IL-6 transsignaling: the in vivo consequences. J. Interferon Cytokine Res. 25, 241-253 (2005).
-
(2005)
J. Interferon Cytokine Res.
, vol.25
, pp. 241-253
-
-
Jones, S.A.1
Richards, P.J.2
Scheller, J.3
Rose-John, S.4
-
54
-
-
36248998247
-
Anaemia in patients with cancer: Role of infammatory activity on iron metabolism and severity of anaemia
-
Jacober ML, Mamoni RL, Lima CS, Dos Anjos BL, Grotto HZ. Anaemia in patients with cancer: role of infammatory activity on iron metabolism and severity of anaemia. Med. Oncol. 24, 323-329 (2007).
-
(2007)
Med. Oncol.
, vol.24
, pp. 323-329
-
-
Jacober, M.L.1
Mamoni, R.L.2
Lima, C.S.3
Dos Anjos, B.L.4
Grotto, H.Z.5
-
55
-
-
0029918835
-
Potential use of recombinant human interleukin-6 in clinical oncology
-
Veldhuis GJ, Willemse PH, Mulder NH, Limburg PC, De Vries EG. Potential use of recombinant human interleukin-6 in clinical oncology. Leuk. Lymphoma 20, 373-379 (1996).
-
(1996)
Leuk. Lymphoma
, vol.20
, pp. 373-379
-
-
Veldhuis, G.J.1
Willemse, P.H.2
Mulder, N.H.3
Limburg, P.C.4
De Vries, E.G.5
-
56
-
-
70450214396
-
The role of hepcidin in iron metabolism
-
Nemeth E, Ganz T. The role of hepcidin in iron metabolism. Acta Haematol. 122, 78-86 (2009).
-
(2009)
Acta Haematol.
, vol.122
, pp. 78-86
-
-
Nemeth, E.1
Ganz, T.2
-
57
-
-
67650116365
-
Clinical value of blocking IL-6 receptor
-
Mima T, Nishimoto N. Clinical value of blocking IL-6 receptor. Curr. Opin Rheumatol. 21, 224-230 (2009).
-
(2009)
Curr. Opin Rheumatol.
, vol.21
, pp. 224-230
-
-
Mima, T.1
Nishimoto, N.2
-
58
-
-
2342510407
-
IL-6 mediates hypoferremia of infammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK. IL-6 mediates hypoferremia of infammation by inducing the synthesis of the iron regulatory hormone hepcidin. J. Clin. Invest. 113, 1271-1276 (2004).
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
Keller, C.4
Taudorf, S.5
Pedersen, B.K.6
-
59
-
-
0025977917
-
Monoclonal antibodies to the soluble human IL-6 receptor: Affnity purifcation, ELISA, and inhibition of ligand binding
-
Novick D, Engelmann H, Revel M, Leitner O, Rubinstein M. Monoclonal antibodies to the soluble human IL-6 receptor: affnity purifcation, ELISA, and inhibition of ligand binding. Hybridoma 10, 137-146 (1999).
-
(1999)
Hybridoma
, vol.10
, pp. 137-146
-
-
Novick, D.1
Engelmann, H.2
Revel, M.3
Leitner, O.4
Rubinstein, M.5
-
60
-
-
2642558925
-
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial
-
Nishimoto N, Yoshizaki K, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T. Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum. 50, 1761-1769 (2004).
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 1761-1769
-
-
Nishimoto, N.1
Yoshizaki, K.2
Miyasaka, N.3
Yamamoto, K.4
Kawai, S.5
Takeuchi, T.6
-
61
-
-
0030960980
-
Preliminary defnition of improvement in juvenile arthritis
-
Giannini EH, Ruperto N, Ravelli A, Lovell DJ, Felson DT, Martini A. Preliminary defnition of improvement in juvenile arthritis. Arthritis Rheum. 40, 1202-1209 (1997).
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 1202-1209
-
-
Giannini, E.H.1
Ruperto, N.2
Ravelli, A.3
Lovell, D.J.4
Felson, D.T.5
Martini, A.6
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