Transcriptional regulation of the heterocyst patterning gene patA from Anabaena sp. strain PCC 7120

Journal of Bacteriology

Volumn 192, Issue 18, 2010, Pages 4732-4740

  Young Robbins, Shirley S ^a,c   Risser, Douglas D ^a,d   Moran, Jennifer R ^b   Haselkorn, Robert ^b   Callahan, Sean M ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF HAWAII   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITROGEN; NUCLEOTIDE; BACTERIAL PROTEIN; PATA PROTEIN, ANABAENA;

ANABAENA; ANIMAL CELL; ARTICLE; CELL DIVISION; CELL STRUCTURE; GENE DELETION; GENE MUTATION; MICROFILAMENT; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; NUCLEIC ACID AMPLIFICATION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROMOTER REGION;

ANABAENA SP.;

ANABAENA; BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; NUCLEIC ACID AMPLIFICATION TECHNIQUES; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

EID: 77956505657     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.00577-10     Document Type: Article

References (27)

1. Aravind, L., and E. V. Koonin. 2002. Classification of the caspase-hemoglobinase fold: detection of new families and implications for the origin of the eukaryotic separins. Proteins 46:355-367.
2. Black, T. A., Y. Cai, and C. P. Wolk. 1993. Spatial expression and autoregulation of hetR, a gene involved in the control of heterocyst development in Anabaena. Mol. Microbiol. 9:77-84.
3. Borthakur, P. B., C. C. Orozco, S. S. Young-Robbins, R. Haselkorn, and S. M. Callahan. 2005. Inactivation of patS and hetN causes lethal levels of heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. PCC 7120. Mol. Microbiol. 57:111-123.
4. Buikema, W. J., and R. Haselkorn. 2001. Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions. Proc. Natl. Acad. Sci. U. S. A. 98:2729-2734.
5. Callahan, S. M., and W. J. Buikema. 2001. The role of HetN in maintenance of the heterocyst pattern in Anabaena sp. PCC 7120. Mol. Microbiol. 40:941-950.
6. Ehira, S., and M. Ohmori. 2006. NrrA directly regulates expression of hetR during heterocyst differentiation in the cyanobacterium Anabaena sp. strain PCC 7120. J. Bacteriol. 188:8520-8525.
7. Elhai, J., and C. P. Wolk. 1988. Conjugal transfer of DNA to cyanobacteria. Methods Enzymol. 167:747-754.
8. Higuchi, R., B. Krummel, and R. K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res. 16:7351-7367.
9. Huang, X., Y. Dong, and J. Zhao. 2004. HetR homodimer is a DNA-binding protein required for heterocyst differentiation, and the DNA-binding activity is inhibited by PatS. Proc. Natl. Acad. Sci. U. S. A. 101:4848-4853.
10. Liang, J., L. Scappino, and R. Haselkorn. 1992. The patA gene product, which contains a region similar to CheY of Escherichia coli, controls heterocyst pattern formation in the cyanobacterium Anabaena 7120. Proc. Natl. Acad. Sci. U. S. A. 89:5655-5659.
11. Makarova, K. S., E. V. Koonin, R. Haselkorn, and M. Y. Galperin. 2006. Cyanobacterial response regulator PatA contains a conserved N-terminal domain (PATAN) with an alpha-helical insertion. Bioinformatics 22:1297-1301.
12. + by cyanobacteria with and without heterocysts. J. Bacteriol. 134:125-130.
13. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
14. Muro-Pastor, A. M., A. Valladares, E. Flores, and A. Herrero. 2002. Mutual dependence of the expression of the cell differentiation regulatory protein HetR and the global nitrogen regulator NtcA during heterocyst development. Mol. Microbiol. 44:1377-1385.
15. Orozco, C. C., D. D. Risser, and S. M. Callahan. 2006. Epistasis analysis of four genes from Anabaena sp. strain PCC 7120 suggests a connection between PatA and PatS in heterocyst pattern formation. J. Bacteriol. 188:1808-1816.
16. Rajagopalan, R., and S. M. Callahan. 2010. Temporal and spatial regulation of the four transcription start sites of hetR from Anabaena sp. strain PCC 7120. J. Bacteriol. 192:1088-1096.
17. Risser, D. D., and S. M. Callahan. 2008. HetF and PatA control levels of HetR in Anabaena sp. strain PCC 7120. J. Bacteriol. 190:7645-7654.
18. Risser, D. D., and S. M. Callahan. 2007. Mutagenesis of hetR reveals amino acids necessary for HetR function in the heterocystous cyanobacterium Anabaena sp. strain PCC 7120. J. Bacteriol. 189:2460-2467.
19. Sakr, S., R. Jeanjean, C.-C. Zhang, and T. Arcondeguy. 2006. Inhibition of cell division suppresses heterocyst development in Anabaena sp. strain PCC 7120. J. Bacteriol. 188:1396-1404.
20. Schaefer, M. R., and S. S. Golden. 1989. Differential expression of members of a cyanobacterial psbA gene family in response to light. J. Bacteriol. 171:3973-3981.
21. Wang, Y., and X. Xu. 2005. Regulation of hetC of genes required for heterocyst differentiation and cell division in Anabaena sp. strain PCC 7120. J. Bacteriol. 187:8489-8493.
22. Wei, T.-F., R. Ramasubramanian, and J. W. Golden. 1994. Anabaena sp. strain PCC 7120 ntcA gene required for growth on nitrate and heterocyst development. J. Bacteriol. 176:4473-4482.
23. Wolk, C. P. 1968. Movement of carbon from vegetative cells to heterocysts in Anabaena cylindrica. J. Bacteriol. 96:2138-2143.
24. Wolk, C. P., A. Ernst, and J. Elhai. 1994. Heterocyst metabolism and development, p. 769-823. In D. A. Bryant (ed.), The molecular biology of cyanobacteria, vol. 1. Kluwer Academic Publishers, Dordrecht, Netherlands.
25. Wong, F. C. Y., and J. C. Meeks. 2001. The hetF gene product is essential to heterocyst differentiation and affects HetR function in the cyanobacterium Nostoc punctiforme. J. Bacteriol. 183:2654-2661.
26. Yoon, H.-S., and J. W. Golden. 1998. Heterocyst pattern formation controlled by a diffusible peptide. Science 282:935-938.
27. Zhang, W., Y. Du, I. Khudyakov, Q. Fan, H. Gao, D. Ning, C. P. Wolk, and X. Xu. 2007. A gene cluster that regulates both heterocyst differentiation and pattern formation in Anabaena sp. strain PCC 7120. Mol. Microbiol. 66:1429-1443.