A practical synthesis of 1,2-nitroamines by Michael addition of N-nucleophiles to nitroalkenes

Synthesis

Volumn , Issue 18, 2010, Pages 3138-3142

  Robiette, Raphaël ^a   Tran, Trieu Van ^a   Cordi, Alex ^b   Tinant, Bernard ^a   Marchand Brynaert, Jacqueline ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

amines; azides; Michael addition; nitro amines; nitroalkenes

Indexed keywords

ALKYL DERIVATIVES; AZIDES; GOOD YIELD; HIGH YIELD; MICHAEL ADDITIONS; NITRO-AMINES; NITROALKENES; PHASE TRANSFER CATALYSIS; PRACTICAL METHOD;

ADDITION REACTIONS; CATALYSIS; REACTION KINETICS; SYNTHESIS (CHEMICAL);

AMINES;

(1 AZIDO 2 NITROETHYL)BENZENE; 1 (1 NITROOCATAN 2 YL) 1H BENZO[D][1,2,3]TRIAZOLE; 1 (2 NITRO 1 PHENYLETHYL) 1H BENZO[D][1,2,3]TRIAZOLE; 1 AMINOMETHYLCYCLOHEXYLAMINE DIHYDROCHLORIDE; 1 AZIDO 1 (NITROMETHYL)CYCLOHEXANE; 1 PHENYLETHANE 1,2 DIAMINE DIHYDROCHLORIDE; 1,2 NITROAMINE DERIVATIVE; 2 (1 NITROOCATAN 2 YL) 1H BENZO[D][1,2,3]TRIAZOLE; 2 (2 NITRO 1 PHENYLETHYL) 2H BENZO[D][1,2,3]TRIAZOLE; 2 AZIDO 1 NITROBUTANE; 2 AZIDO 1 NITROOCTANE; 2 AZIDO 3,3 DIMETHYL 1 NITROBUTANE; ALKENE DERIVATIVE; AMINE; BENZOTRIAZOLE DERIVATIVE; NITROALKENE; NUCLEOPHILE; O BENZYL N (1 NITROOCTAN 2 YL)HYDROXYLAMINE; O BENZYL N (2 NITRO 1 PHENYLETHYL)HYDROXYLAMINE; OCTANE 1,2 DIAMINE DIHYDROCHLORIDE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHEMICAL INTERACTION; CHEMICAL REACTION KINETICS; COMPLEX FORMATION; DEPROTECTION REACTION; MICHAEL ADDITION; SYNTHESIS;

EID: 77956468991     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258176     Document Type: Article

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